PMID- 29477915
OWN - NLM
STAT- MEDLINE
DCOM- 20181031
LR  - 20201216
IS  - 1872-6232 (Electronic)
IS  - 0378-3782 (Linking)
VI  - 118
DP  - 2018 Mar
TI  - Prediction of neurodevelopment at one year of age using the General Movements 
      assessment in the neonatal surgical population.
PG  - 42-47
LID - S0378-3782(17)30646-1 [pii]
LID - 10.1016/j.earlhumdev.2018.02.001 [doi]
AB  - BACKGROUND: Recent evidence indicates neonatal surgery is associated with an 
      increased risk of neurodevelopmental disability, including cerebral palsy (CP). 
      Despite evidence for prediction of CP there is limited information on use of the 
      General Movements Assessment (GMA) with this population. AIM: To investigate the 
      utility of the GMA for prediction of neurodevelopment in an infant surgical 
      population. STUDY DESIGN: Prospective cohort study Subjects: 278 infants 
      following cardiac surgery (n = 149), non-cardiac surgery (n = 123) or both 
      surgeries (n = 6). OUTCOME MEASURES: GMA at three months of age (mean 12 weeks, 
      SD 1.6) rated by three assessors, two blinded to clinical details. Follow-up at 
      one year of age (mean 372 days, SD 13) using Bayley Scales of Infant and Toddler 
      Development III (BSID-III), clinical and neurological examination. RESULTS: At 
      one year, none of the 248 (89%) infants with normal fidgety movements had a 
      diagnosis of CP, however a large proportion (n = 118, 48%) demonstrated delayed 
      development. Infants who had absent fidgety movements (n = 25, 9%) showed a 
      significant difference on all subtests of the BSID-III (p > 0.05). For prediction 
      of CP there was 100% sensitivity and 96% specificity. CONCLUSIONS: The GMA is a 
      valid complementary assessment tool to enhance prediction of neurodevelopment, 
      specifically CP, following early neonatal surgery and should be incorporated into 
      routine follow-up for this population.
CI  - Copyright (c) 2018 Elsevier B.V. All rights reserved.
FAU - Crowle, Cathryn
AU  - Crowle C
AD  - Grace Centre for Newborn Intensive Care, The Children's Hospital Westmead, 
      Australia; The University of Sydney, Australia. Electronic address: 
      Cathryn.crowle@health.nsw.gov.au.
FAU - Galea, Claire
AU  - Galea C
AD  - Cerebral Palsy Research Institute, Sydney, Australia.
FAU - Walker, Karen
AU  - Walker K
AD  - Grace Centre for Newborn Intensive Care, The Children's Hospital Westmead, 
      Australia; Cerebral Palsy Research Institute, Sydney, Australia; The University 
      of Sydney, Australia.
FAU - Novak, Iona
AU  - Novak I
AD  - Cerebral Palsy Research Institute, Sydney, Australia; The University of Sydney, 
      Australia.
FAU - Badawi, Nadia
AU  - Badawi N
AD  - Grace Centre for Newborn Intensive Care, The Children's Hospital Westmead, 
      Australia; Cerebral Palsy Research Institute, Sydney, Australia; The University 
      of Sydney, Australia.
LA  - eng
PT  - Journal Article
DEP - 20180223
PL  - Ireland
TA  - Early Hum Dev
JT  - Early human development
JID - 7708381
SB  - IM
MH  - *Child Development
MH  - Developmental Disabilities/diagnosis/*epidemiology
MH  - Female
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Laparotomy/adverse effects
MH  - Male
MH  - *Movement
MH  - Postoperative Complications/diagnosis/*epidemiology
MH  - Thoracic Surgical Procedures/adverse effects
EDAT- 2018/02/27 06:00
MHDA- 2018/11/01 06:00
CRDT- 2018/02/26 06:00
PHST- 2017/12/14 00:00 [received]
PHST- 2018/02/01 00:00 [revised]
PHST- 2018/02/01 00:00 [accepted]
PHST- 2018/02/27 06:00 [pubmed]
PHST- 2018/11/01 06:00 [medline]
PHST- 2018/02/26 06:00 [entrez]
AID - S0378-3782(17)30646-1 [pii]
AID - 10.1016/j.earlhumdev.2018.02.001 [doi]
PST - ppublish
SO  - Early Hum Dev. 2018 Mar;118:42-47. doi: 10.1016/j.earlhumdev.2018.02.001. Epub 
      2018 Feb 23.