PMID- 29479293
OWN - NLM
STAT- MEDLINE
DCOM- 20180926
LR  - 20181113
IS  - 1537-744X (Electronic)
IS  - 2356-6140 (Print)
IS  - 1537-744X (Linking)
VI  - 2018
DP  - 2018
TI  - Predictors for Gingival Index in Middle-Aged Asian Indians with Type 2 Diabetes 
      from South India: A Cross-Sectional Observational Study.
PG  - 9081572
LID - 10.1155/2018/9081572 [doi]
LID - 9081572
AB  - Asian Indians develop type 2 diabetes mellitus (T2DM) much earlier as compared to 
      White Caucasians, due to unique phenotypic and genetic architecture. 
      Periodontitis in T2DM patients is often a neglected clinical feature. This study 
      was conducted to derive predictor variables for gingival index in middle-aged 
      Asian Indians with T2DM in a semiurban population of Dravidian ethnicity from 
      Tamil Nadu, India. T2DM patients (n = 232, mean age: 50.6 +/- 10.4 years) with 
      periodontitis (n = 123, mean age: 54.3 +/- 2.4 years) and without periodontitis (n 
      = 109, mean age: 55.2 +/- 3.1 years) were recruited between 2014 and 2016 by 
      purposive sampling method. Dental examinations for pocket depth (PD) and clinical 
      attachment level (CAL) were performed and gingival index was calculated. Fasting 
      venous blood samples were analysed for measures of glycaemia and cholesterol. 
      Significant positive correlation (p < 0.01) was observed for gingival index with 
      glycosylated haemoglobin (HbA1c), pocket depth, presence of T2DM, and clinical 
      attachment level. Stepwise multiple linear regression analysis derived increased 
      pocket depth (p < 0.01), elevated HbA1c (p < 0.01), clinical attachment level (p 
      < 0.01), and presence of diabetes (p < 0.01) as significant predictors (r(2) 
      value = 0.67) for increased gingival index in middle aged patients with T2DM. 
      These variables significantly (p < 0.01) predispose middle-aged T2DM patients to 
      increased gingival index, thus warranting appropriate intervention.
FAU - Karthik, S Jai
AU  - Karthik SJ
AUID- ORCID: 0000-0001-6437-5328
AD  - Department of Environmental Sciences, Bharathiar University, Coimbatore, Tamil 
      Nadu, India.
AD  - RVS Dental College, Coimbatore, Tamil Nadu, India.
FAU - Anoop, Shajith
AU  - Anoop S
AD  - Department of Environmental Sciences, Bharathiar University, Coimbatore, Tamil 
      Nadu, India.
FAU - Kumar, R Suresh
AU  - Kumar RS
AD  - Suresh Diabetes Centre, Vadavalli, Coimbatore, Tamil Nadu, India.
FAU - Rani, M V Usha
AU  - Rani MVU
AD  - Department of Environmental Sciences, Bharathiar University, Coimbatore, Tamil 
      Nadu, India.
LA  - eng
PT  - Journal Article
DEP - 20180102
PL  - United States
TA  - ScientificWorldJournal
JT  - TheScientificWorldJournal
JID - 101131163
RN  - 0 (Biomarkers)
SB  - IM
MH  - Adult
MH  - Biomarkers
MH  - Cross-Sectional Studies
MH  - Dental Care/statistics & numerical data
MH  - Diabetes Mellitus, Type 2/*epidemiology/metabolism
MH  - Female
MH  - Humans
MH  - India/epidemiology
MH  - Male
MH  - Middle Aged
MH  - *Periodontal Index
MH  - Public Health Surveillance
MH  - Sex Factors
PMC - PMC5816844
EDAT- 2018/02/27 06:00
MHDA- 2018/09/27 06:00
PMCR- 2018/01/02
CRDT- 2018/02/27 06:00
PHST- 2017/06/26 00:00 [received]
PHST- 2017/11/02 00:00 [revised]
PHST- 2017/11/19 00:00 [accepted]
PHST- 2018/02/27 06:00 [entrez]
PHST- 2018/02/27 06:00 [pubmed]
PHST- 2018/09/27 06:00 [medline]
PHST- 2018/01/02 00:00 [pmc-release]
AID - 10.1155/2018/9081572 [doi]
PST - epublish
SO  - ScientificWorldJournal. 2018 Jan 2;2018:9081572. doi: 10.1155/2018/9081572. 
      eCollection 2018.