PMID- 29487872 OWN - NLM STAT- MEDLINE DCOM- 20180824 LR - 20181113 IS - 2314-6141 (Electronic) IS - 2314-6133 (Print) VI - 2018 DP - 2018 TI - A Simplified Ultrasound Comet Tail Grading Scoring to Assess Pulmonary Congestion in Patients with Heart Failure. PG - 8474839 LID - 10.1155/2018/8474839 [doi] LID - 8474839 AB - Ultrasound lung comets (ULCs) are a nonionizing bedside approach to assess extravascular lung water. We evaluated a protocol for grading ULC score to estimate pulmonary congestion in heart failure patients and investigated clinical and echocardiographic correlates of the ULC score. Ninety-three patients with congestive heart failure, admitted to the emergency department, underwent pulmonary ultrasound and echocardiography. A ULC score was obtained by summing the ULC scores of 7 zones of anterolateral chest scans. The results of ULC score were compared with echocardiographic results, the New York Heart Association (NYHA) functional classification, radiologic score, and N-terminal pro-b-type natriuretic peptide (NT-proBNP). Positive linear correlations were found between the 7-zone ULC score and the following: E/e', systolic pulmonary artery pressure, severity of mitral regurgitation, left ventricular global longitudinal strain, NYHA functional classification, radiologic score, and NT-proBNP. However, there was no significant correlation between ULC score and left ventricular ejection fraction, left ventricle diameter, left ventricular volume, or left atrial volume. A multivariate analysis identified the E/e', systolic pulmonary artery pressure, and radiologic score as the only independent variables associated with ULC score increase. The simplified 7-zone ULC score is a rapid and noninvasive method to assess lung congestion. Diastolic rather than systolic performance may be the most important determinant of the degree of lung congestion in patients with heart failure. FAU - Li, Hong AU - Li H AD - Department of Ultrasound, Shanxi Provincial People's Hospital, Taiyuan 030012, China. FAU - Li, Yi-Dan AU - Li YD AD - Department of Echocardiography, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China. FAU - Zhu, Wei-Wei AU - Zhu WW AD - Department of Echocardiography, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China. FAU - Kong, Ling-Yun AU - Kong LY AD - Department of Echocardiography, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China. FAU - Ye, Xiao-Guang AU - Ye XG AD - Department of Echocardiography, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China. FAU - Cai, Qi-Zhe AU - Cai QZ AD - Department of Echocardiography, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China. FAU - Sun, Lan-Lan AU - Sun LL AD - Department of Echocardiography, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China. FAU - Lu, Xiu-Zhang AU - Lu XZ AUID- ORCID: 0000-0001-9566-9484 AD - Department of Echocardiography, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China. LA - eng PT - Journal Article DEP - 20180102 PL - United States TA - Biomed Res Int JT - BioMed research international JID - 101600173 RN - 0 (Peptide Fragments) RN - 0 (pro-brain natriuretic peptide (1-76)) RN - 114471-18-0 (Natriuretic Peptide, Brain) SB - IM MH - Aged MH - Echocardiography/methods MH - Extravascular Lung Water/metabolism/physiology MH - Female MH - Heart Failure/metabolism/*physiopathology MH - Heart Ventricles/metabolism/physiopathology MH - Humans MH - Lung/metabolism/*physiopathology MH - Male MH - Natriuretic Peptide, Brain/metabolism MH - Peptide Fragments/metabolism MH - Prospective Studies MH - Pulmonary Circulation/physiology MH - Pulmonary Edema/metabolism/physiopathology MH - Ultrasonography/methods MH - Ventricular Function, Left/physiology PMC - PMC5816880 EDAT- 2018/03/01 06:00 MHDA- 2018/08/25 06:00 PMCR- 2018/01/02 CRDT- 2018/03/01 06:00 PHST- 2017/08/07 00:00 [received] PHST- 2017/11/23 00:00 [revised] PHST- 2017/12/03 00:00 [accepted] PHST- 2018/03/01 06:00 [entrez] PHST- 2018/03/01 06:00 [pubmed] PHST- 2018/08/25 06:00 [medline] PHST- 2018/01/02 00:00 [pmc-release] AID - 10.1155/2018/8474839 [doi] PST - epublish SO - Biomed Res Int. 2018 Jan 2;2018:8474839. doi: 10.1155/2018/8474839. eCollection 2018.