PMID- 29489667
OWN - NLM
STAT- MEDLINE
DCOM- 20180313
LR  - 20210109
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 97
IP  - 9
DP  - 2018 Mar
TI  - Predictors of mortality in ST-elevation MI patients: A prospective study.
PG  - e0065
LID - 10.1097/MD.0000000000010065 [doi]
LID - e0065
AB  - We aimed to define factors predicting mortality in patients having ST elevation 
      myocardial infarction (STEMI) who had Primary Percutaneous Coronary Intervention 
      (PCI) in our setting.This is a prospective study on patients presenting to the 
      emergency department with STEMI who underwent PCI during a 12-month period. 
      Physiological parameters were calculated using the vital signs and age of 
      patients. Time-based factors in the institutional protocol were collected. 
      Univariate analysis was performed to define significant factors that affected 
      mortality. Significant factors were then entered into a logistic regression 
      model. Factors significantly affecting mortality were defined. Receiving 
      operating characteristic curve was applied to define the best predictors of 
      mortality.A total of 167 consecutive patients were studied; 128 (76.6%) were 
      males. The mean (SD) age of the patients was 61.9 (12.8) years. The logistic 
      regression model showed that significant factors were age (P = .002), Modified 
      Shock Index, MSI (P = .028), systolic blood pressure (P = .028), and time between 
      consultation and activation of catheter laboratory (P = .047). The cut-off points 
      with best prediction of mortality were age of 71.5 years, systolic blood pressure 
      of less than 95 mmHg, MSI of 0.85, and a time more than 3.5 minutes between 
      consultation and activation of catheter laboratory.Our study shows that 
      significant predictors of 30-days mortality of STEMI were age, systolic blood 
      pressure on presentation, MSI, and the time between consultation and catheter 
      laboratory activation. Improving prehospital resuscitation and activation of the 
      catheter laboratory by emergency physicians may reduce mortality in our setting.
FAU - Zorbozan, Onur
AU  - Zorbozan O
AD  - Department of Emergency Medicine, Eskisehir Osmangazi University, College of 
      Medicine and Health Sciences, Eskisehir, Turkey Departments of Internal Medicine, 
      College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, 
      United Arab Emirates Department of Cardiology, Eskisehir Osmangazi University, 
      College of Medicine and Health Sciences, Eskisehir, Turkey Department of Surgery, 
      College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, 
      United Arab Emirates.
FAU - Cevik, Arif A
AU  - Cevik AA
FAU - Acar, Nurdan
AU  - Acar N
FAU - Ozakin, Engin
AU  - Ozakin E
FAU - Ozcelik, Hamit
AU  - Ozcelik H
FAU - Birdane, Alparslan
AU  - Birdane A
FAU - Abu-Zidan, Fikri M
AU  - Abu-Zidan FM
LA  - eng
PT  - Journal Article
PT  - Observational Study
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - IM
MH  - Aged
MH  - Area Under Curve
MH  - Female
MH  - Hospital Mortality
MH  - Humans
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Percutaneous Coronary Intervention/*mortality
MH  - Prospective Studies
MH  - ST Elevation Myocardial Infarction/*mortality/surgery
PMC - PMC5851714
COIS- The authors declare no conflicts of interest.
EDAT- 2018/03/01 06:00
MHDA- 2018/03/14 06:00
PMCR- 2018/03/02
CRDT- 2018/03/01 06:00
PHST- 2018/03/01 06:00 [entrez]
PHST- 2018/03/01 06:00 [pubmed]
PHST- 2018/03/14 06:00 [medline]
PHST- 2018/03/02 00:00 [pmc-release]
AID - 00005792-201803020-00028 [pii]
AID - MD-D-17-03574 [pii]
AID - 10.1097/MD.0000000000010065 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2018 Mar;97(9):e0065. doi: 10.1097/MD.0000000000010065.