PMID- 29492434
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220316
IS  - 2363-9024 (Electronic)
IS  - 2363-9024 (Linking)
VI  - 2
IP  - 1
DP  - 2016
TI  - Lactate level during cardiopulmonary bypass as a predictor of postoperative 
      outcomes in adult patients undergoing cardiac surgery.
PG  - 39
LID - 10.1186/s40981-016-0064-3 [doi]
LID - 39
AB  - BACKGROUND: It has been reported that prolonged intensive care unit (ICU) stay 
      after cardiac surgery is associated with poor patient outcome. In addition, 
      prolonged stay can block the efficient use of ICU beds with an increase in 
      expenditure of health-care costs. The aim of the present study was to 
      retrospectively determine which pre- and intra-operative factors could 
      significantly affect ICU-free survival days (IFSD) which has been suggested to 
      reflect postoperative patients' outcome, as well as variables significantly 
      associated with the main predictors of IFSD. FINDINGS: We reviewed anesthesia 
      charts and medical records of 145 patients undergoing cardiac surgery under 
      cardiopulmonary bypass (CPB) in our hospital from January 2014 to October 2015, 
      and 72 patients' records were finally used for the analysis. IFSD was a median of 
      25 days (95% CI 24-26). The multiple regression analysis indicated that 
      preoperative estimated glomerular filtration rate, differences between 
      preoperative mean arterial pressure and mean CPB pressure, and blood lactate 
      level at 2 h after CPB (CPB-2 h) were independently associated with IFSD (beta 
      regression coefficients 0.086, -0.083, and -3.601, respectively). CONCLUSION: In 
      addition to preoperative renal function and differences between preoperative MAP 
      and CPB pressure, the lactate level at CPB-2 h could be a major predictor of 
      postoperative outcome in patients undergoing cardiac surgery.
FAU - Noguchi, Satoko
AU  - Noguchi S
AD  - Department of Anesthesiology, Hirosaki University Graduate School of Medicine, 5 
      Zaifucho, Hirosaki, 036-8562 Japan.
FAU - Saito, Junichi
AU  - Saito J
AD  - Department of Anesthesiology, Hirosaki University Graduate School of Medicine, 5 
      Zaifucho, Hirosaki, 036-8562 Japan.
FAU - Hashiba, Eiji
AU  - Hashiba E
AD  - Department of Anesthesiology, Hirosaki University Graduate School of Medicine, 5 
      Zaifucho, Hirosaki, 036-8562 Japan.
FAU - Kushikata, Tetsuya
AU  - Kushikata T
AD  - Department of Anesthesiology, Hirosaki University Graduate School of Medicine, 5 
      Zaifucho, Hirosaki, 036-8562 Japan.
FAU - Hirota, Kazuyoshi
AU  - Hirota K
AD  - Department of Anesthesiology, Hirosaki University Graduate School of Medicine, 5 
      Zaifucho, Hirosaki, 036-8562 Japan.
LA  - eng
PT  - Journal Article
DEP - 20161124
PL  - Germany
TA  - JA Clin Rep
JT  - JA clinical reports
JID - 101682121
PMC - PMC5813764
OTO - NOTNLM
OT  - Blood lactate level
OT  - Cardiac surgery
OT  - ICU-free survival days
EDAT- 2016/01/01 00:00
MHDA- 2016/01/01 00:01
PMCR- 2016/11/24
CRDT- 2018/03/02 06:00
PHST- 2016/08/19 00:00 [received]
PHST- 2016/11/15 00:00 [accepted]
PHST- 2018/03/02 06:00 [entrez]
PHST- 2016/01/01 00:00 [pubmed]
PHST- 2016/01/01 00:01 [medline]
PHST- 2016/11/24 00:00 [pmc-release]
AID - 64 [pii]
AID - 10.1186/s40981-016-0064-3 [doi]
PST - ppublish
SO  - JA Clin Rep. 2016;2(1):39. doi: 10.1186/s40981-016-0064-3. Epub 2016 Nov 24.