PMID- 2949750 OWN - NLM STAT- MEDLINE DCOM- 19870305 LR - 20201209 IS - 0067-8694 (Print) IS - 0067-8694 (Linking) VI - 51 DP - 1986 TI - The receptor for immunoglobulin E as a membrane protein. PG - 59-67 AB - Mast cells and related cells have a surface glycoprotein that avidly binds monomeric immunoglobulin E (IgE). This protein is more complex than originally thought, its analysis having been complicated by its lability in mild detergents. The properties of this receptor, especially with respect to its interaction with lipids and detergents, is reviewed and the implications for the study of other membrane protein systems are discussed. FAU - Metzger, H AU - Metzger H FAU - Alcaraz, G AU - Alcaraz G FAU - Kinet, J P AU - Kinet JP FAU - Quarto, R AU - Quarto R LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Biochem Soc Symp JT - Biochemical Society symposium JID - 7506896 RN - 0 (Detergents) RN - 0 (Membrane Proteins) RN - 0 (Phospholipids) RN - 0 (Receptors, Fc) RN - 0 (Receptors, IgE) RN - 0 (Receptors, Immunologic) RN - 37341-29-0 (Immunoglobulin E) RN - 3WJQ0SDW1A (Polyethylene Glycols) RN - 9002-93-1 (Octoxynol) RN - 9036-19-5 (Nonidet P-40) SB - IM MH - Detergents MH - Electrophoresis, Polyacrylamide Gel MH - Immunoglobulin E MH - Membrane Proteins/*isolation & purification MH - Octoxynol MH - Phospholipids MH - Polyethylene Glycols MH - Receptors, Fc/*isolation & purification MH - Receptors, IgE MH - Receptors, Immunologic/*isolation & purification EDAT- 1986/01/01 00:00 MHDA- 1986/01/01 00:01 CRDT- 1986/01/01 00:00 PHST- 1986/01/01 00:00 [pubmed] PHST- 1986/01/01 00:01 [medline] PHST- 1986/01/01 00:00 [entrez] PST - ppublish SO - Biochem Soc Symp. 1986;51:59-67.