PMID- 29497999 OWN - NLM STAT- MEDLINE DCOM- 20181224 LR - 20210624 IS - 1559-0720 (Electronic) IS - 0163-4984 (Linking) VI - 186 IP - 1 DP - 2018 Nov TI - Supplementation of Cr Methionine During Dry Period of Dairy Cows and Its Effect on Some Production and Biochemical Parameters During Early Lactation and on Immunity of Their Offspring. PG - 143-153 LID - 10.1007/s12011-018-1279-0 [doi] AB - This study aimed to investigate the effect of dietary chromium methionine (Cr-Met) supplementation on the production and immunological parameters of dairy cows during the dry and postpartum period and their offspring. Forty-five Holstein transition cows were randomly assigned to experimental groups with control, positive control (levamisole-injected cows), and treatment groups (5 g dietary Cr-Met/day/cow). Production, immunological, and biochemical parameters were analyzed during the dry and postpartum period. Result revealed that in dry cows, monocyte count and serum glucose level significantly (p < 0.05) decrease in Cr-supplemented cows over control. Similarly, after parturition, the numbers of all immune cells (except monocytes) decreased significantly (p < 0.05); however, serum IgG, ALT, AST, glucose levels, and total leucocyte, neutrophil, and leucocyte count were increased significantly (p < 0.05) in Cr-supplemented cows over the control group. Days in milk (DIM) of treatment cows were significantly (p < 0.05) decreased over the control group; however, no significant (p > 0.05) differences were observed on milk production, colostrum, and IgG concentrations. As a conclusion, the supplementation of Cr had positive effects on immune cells of cows after parturition; however, serum biochemical parameters remained unaffected. Also, there were significant differences on the number of total leucocyte and neutrophil, on the activity of ALT at birthday, and on the number of total leucocyte at postpartum for calves. FAU - Gultepe, Eyup Eren AU - Gultepe EE AD - Department of Animal Nutrition and Nutritional Diseases, Afyon Kocatepe University, 03200, Afyonkarahisar, Turkey. eegultepe@gmail.com. FAU - Uyarlar, Cangir AU - Uyarlar C AD - Department of Animal Nutrition and Nutritional Diseases, Afyon Kocatepe University, 03200, Afyonkarahisar, Turkey. FAU - Bayram, Ismail AU - Bayram I AD - Department of Animal Nutrition and Nutritional Diseases, Afyon Kocatepe University, 03200, Afyonkarahisar, Turkey. LA - eng GR - 14.SAG.BIL.14/Afyon Kocatepe University Scientific Research Projects Commission/ PT - Journal Article DEP - 20180301 PL - United States TA - Biol Trace Elem Res JT - Biological trace element research JID - 7911509 RN - 0R0008Q3JB (Chromium) RN - AE28F7PNPL (Methionine) SB - IM MH - Animals MH - Cattle MH - Chromium/administration & dosage/*pharmacology MH - Dietary Supplements MH - Female MH - Immunity/drug effects MH - Lactation/*drug effects MH - Methionine/administration & dosage/*pharmacology OTO - NOTNLM OT - Colostrum OT - Dairy calf OT - Immunonutrition OT - Milk production OT - Neonatal OT - Organic chromium OT - Trace element EDAT- 2018/03/03 06:00 MHDA- 2018/12/26 06:00 CRDT- 2018/03/03 06:00 PHST- 2017/09/04 00:00 [received] PHST- 2018/02/19 00:00 [accepted] PHST- 2018/03/03 06:00 [pubmed] PHST- 2018/12/26 06:00 [medline] PHST- 2018/03/03 06:00 [entrez] AID - 10.1007/s12011-018-1279-0 [pii] AID - 10.1007/s12011-018-1279-0 [doi] PST - ppublish SO - Biol Trace Elem Res. 2018 Nov;186(1):143-153. doi: 10.1007/s12011-018-1279-0. Epub 2018 Mar 1.