PMID- 29501837
OWN - NLM
STAT- MEDLINE
DCOM- 20190422
LR  - 20200306
IS  - 1873-507X (Electronic)
IS  - 0031-9384 (Print)
IS  - 0031-9384 (Linking)
VI  - 192
DP  - 2018 Aug 1
TI  - Dietary influences on cognition.
PG  - 118-126
LID - S0031-9384(18)30113-6 [pii]
LID - 10.1016/j.physbeh.2018.02.052 [doi]
AB  - Obesity is a world-wide crisis with profound healthcare and socio-economic 
      implications and it is now clear that the central nervous system (CNS) is a 
      target for the complications of metabolic disorders like obesity. In addition to 
      decreases in physical activity and sedentary lifestyles, diet is proposed to be 
      an important contributor to the etiology and progression of obesity. 
      Unfortunately, there are gaps in our knowledge base related to how dietary 
      choices impact the structural and functional integrity of the CNS. For example, 
      while chronic consumption of hypercaloric diets (increased sugars and fat) 
      contribute to increases in body weight and adiposity characteristic of metabolic 
      disorders, the mechanistic basis for neurocognitive deficits in obesity remains 
      to be determined. In addition, studies indicate that acute consumption of 
      hypercaloric diets impairs performance in a wide variety of cognitive domains, 
      even in normal non-obese control subjects. These results from the clinical and 
      basic science literature indicate that diet can have rapid, as well as long 
      lasting effects on cognitive function. This review summarizes our symposium at 
      the 2017 Society for the Study of Ingestive Behavior (SSIB) meeting that 
      discussed these effects of diet on cognition. Collectively, this review 
      highlights the need for integrated and comprehensive approaches to more fully 
      determine how diet impacts behavior and cognition under physiological conditions 
      and in metabolic disorders like type 2 diabetes mellitus (T2DM) and obesity.
CI  - Crown Copyright (c) 2018. Published by Elsevier Inc. All rights reserved.
FAU - Reichelt, A C
AU  - Reichelt AC
AD  - School of Health and Biomedical Science, RMIT University, Melbourne, Victoria 
      3083, Australia.
FAU - Stoeckel, L E
AU  - Stoeckel LE
AD  - National Institute of Diabetes and Digestive and Kidney Diseases, National 
      Institutes of Health, Bethesda, MD, USA.
FAU - Reagan, L P
AU  - Reagan LP
AD  - Department of Pharmacology, Physiology and Neuroscience, University of South 
      Carolina School of Medicine, Columbia, SC 29208, USA; W.J.B. Dorn Veterans 
      Affairs Hospital, Columbia, SC 29208, USA. Electronic address: 
      Lawrence.Reagan@uscmed.sc.edu.
FAU - Winstanley, C A
AU  - Winstanley CA
AD  - Department of Psychology, Djavad Mowafaghian Centre for Brain Health, University 
      of British Columbia, Vancouver, BC, Canada.
FAU - Page, K A
AU  - Page KA
AD  - Department of Internal Medicine, Division of Endocrinology, Keck School of 
      Medicine University of Southern California, Los Angeles, CA, USA.
LA  - eng
GR  - I01 BX001804/BX/BLRD VA/United States
GR  - I01 BX002664/BX/BLRD VA/United States
GR  - R01 DK102794/DK/NIDDK NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20180301
PL  - United States
TA  - Physiol Behav
JT  - Physiology & behavior
JID - 0151504
SB  - IM
MH  - Animals
MH  - Cognition/*physiology
MH  - Cognitive Dysfunction/*etiology/*physiopathology
MH  - Congresses as Topic
MH  - Diet/*adverse effects
MH  - Humans
PMC - PMC6071323
MID - NIHMS951395
OTO - NOTNLM
OT  - Dementia
OT  - Diabetes
OT  - Fructose
OT  - Impassivity
OT  - Insulin
OT  - Obesity
COIS- The authors have no conflicts of interest to declare.
EDAT- 2018/03/05 06:00
MHDA- 2019/04/23 06:00
PMCR- 2019/08/01
CRDT- 2018/03/05 06:00
PHST- 2017/12/20 00:00 [received]
PHST- 2018/02/27 00:00 [revised]
PHST- 2018/02/28 00:00 [accepted]
PHST- 2018/03/05 06:00 [pubmed]
PHST- 2019/04/23 06:00 [medline]
PHST- 2018/03/05 06:00 [entrez]
PHST- 2019/08/01 00:00 [pmc-release]
AID - S0031-9384(18)30113-6 [pii]
AID - 10.1016/j.physbeh.2018.02.052 [doi]
PST - ppublish
SO  - Physiol Behav. 2018 Aug 1;192:118-126. doi: 10.1016/j.physbeh.2018.02.052. Epub 
      2018 Mar 1.