PMID- 29502539
OWN - NLM
STAT- MEDLINE
DCOM- 20190403
LR  - 20190403
IS  - 1475-2662 (Electronic)
IS  - 0007-1145 (Linking)
VI  - 119
IP  - 9
DP  - 2018 May
TI  - Dietary inflammatory index and risk of oesophageal cancer in Xinjiang Uyghur 
      Autonomous Region, China.
PG  - 1068-1075
LID - 10.1017/S0007114518000405 [doi]
AB  - Diet has been shown to have an effect on both inflammation and oesophageal 
      cancer. This study investigated the association between the dietary inflammatory 
      index (DII(R)) and the risk of oesophageal cancer in Xinjiang Uyghur Autonomous 
      Region, China. A case-control study was conducted during 2008-2009 in Urumqi and 
      Shihezi. DII scores were calculated based on dietary intake assessed by a 
      validated FFQ administered to 359 incident oesophageal cancer patients and 380 
      hospital-based controls. Higher DII scores indicate more pro-inflammatory diets. 
      Logistic regression analyses were performed to assess the association between DII 
      scores and oesophageal cancer risk. Oesophageal cancer patients had a 
      significantly higher median DII score (-0.35; interquartile range (IQR)=-2.25, 
      1.86) than that of controls (-1.41; IQR -3.07, 0.40). Multivariable logistic 
      analysis revealed a positive association between higher DII scores and 
      oesophageal cancer risk (ORQuartile 4 v. 1 2.55; 95 % CI 1.61, 4.06; P 
      trend<0.001). A pro-inflammatory diet appears to be associated with an increased 
      risk of oesophageal cancer in Xinjiang Uyghur Autonomous Region. Specific 
      carcinogenic mechanisms are discussed. Accumulating evidence, to which the study 
      contributes, indicates that encouraging the intake of more anti-inflammatory 
      foods may be a strategy to protect against oesophageal cancer in this high-risk 
      area of China.
FAU - Tang, Li
AU  - Tang L
AD  - 1Chinese Evidence-based Medicine Center,West China Hospital,Sichuan 
      University,Chengdu 610041,People's Republic of China.
FAU - Shivappa, Nitin
AU  - Shivappa N
AD  - 2Cancer Prevention and Control Program,University of South Carolina,Columbia,SC 
      29208,USA.
FAU - Hebert, James R
AU  - Hebert JR
AD  - 2Cancer Prevention and Control Program,University of South Carolina,Columbia,SC 
      29208,USA.
FAU - Lee, Andy H
AU  - Lee AH
AD  - 5School of Public Health,Curtin University,Perth,WA 6845,Australia.
FAU - Xu, Fenglian
AU  - Xu F
AD  - 6Faculty of Health,University of Technology Sydney,Sydney, NSW 2007,Australia.
FAU - Binns, Colin W
AU  - Binns CW
AD  - 5School of Public Health,Curtin University,Perth,WA 6845,Australia.
LA  - eng
GR  - R44 DK103377/DK/NIDDK NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20180305
PL  - England
TA  - Br J Nutr
JT  - The British journal of nutrition
JID - 0372547
SB  - IM
MH  - Aged
MH  - Case-Control Studies
MH  - China/epidemiology
MH  - Diet/*adverse effects
MH  - Diet Surveys
MH  - Esophageal Neoplasms/*epidemiology/*etiology
MH  - Female
MH  - Food Analysis
MH  - Humans
MH  - Inflammation/*complications
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Risk Factors
OTO - NOTNLM
OT  - DII dietary inflammatory index
OT  - EAC oesophageal adenocarcinoma
OT  - ESCC oesophageal squamous cell cancer
OT  - China
OT  - Dietary inflammatory index
OT  - Oesophageal cancer
OT  - Xinjiang
EDAT- 2018/03/06 06:00
MHDA- 2019/04/04 06:00
CRDT- 2018/03/06 06:00
PHST- 2018/03/06 06:00 [pubmed]
PHST- 2019/04/04 06:00 [medline]
PHST- 2018/03/06 06:00 [entrez]
AID - S0007114518000405 [pii]
AID - 10.1017/S0007114518000405 [doi]
PST - ppublish
SO  - Br J Nutr. 2018 May;119(9):1068-1075. doi: 10.1017/S0007114518000405. Epub 2018 
      Mar 5.