PMID- 29511381 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240313 IS - 1741-427X (Print) IS - 1741-4288 (Electronic) IS - 1741-427X (Linking) VI - 2017 DP - 2017 TI - Could We Really Use Aloe vera Food Supplements to Treat Diabetes? Quality Control Issues. PG - 4856412 LID - 10.1155/2017/4856412 [doi] LID - 4856412 AB - Diabetes UK has recently listed a number of herbs and spices that have been clinically shown to improve blood glucose control in type-2 diabetes patients and the diabetes high-risk group. With Aloe vera being top in this list, its health benefit along with health and beauty/food retailers supplying it was illustrated in detail. Previous article from this laboratory scrutinised the merit of using A. vera as an alternative therapy to prescription antidiabetic drugs and the risk of using food supplements in the market which do not qualify as drug preparations. In continuation of this discussion, the present study assesses three Aloe Pura brands and one Holland and Barret brand of A. vera juice supplements in the UK market through chromatographic and spectroscopic analysis. While the polysaccharide active ingredient, acemannan, appears to be within the recommended limit, it was found that Aloe Pura (one of the best-selling brands for A. vera supplement) products have benzoate additive that does not appear in the supplement levels. Moreover, two of the Aloe Pura brand juices contain methanol, suggesting that the International Aloe Science Council (IASC) certification does not guarantee the medicinal quality of these products. The therapeutic fitness of such supplements is discussed. FAU - Habtemariam, Solomon AU - Habtemariam S AUID- ORCID: 0000-0001-6743-2244 AD - Pharmacognosy Research Laboratories & Herbal Analysis Services UK, University of Greenwich, Medway Campus, Chatham Maritime, Kent ME4 4TB, UK. LA - eng PT - Journal Article DEP - 20171206 PL - United States TA - Evid Based Complement Alternat Med JT - Evidence-based complementary and alternative medicine : eCAM JID - 101215021 PMC - PMC5736930 EDAT- 2017/01/01 00:00 MHDA- 2017/01/01 00:01 PMCR- 2017/12/06 CRDT- 2018/03/08 06:00 PHST- 2017/09/08 00:00 [received] PHST- 2017/11/05 00:00 [accepted] PHST- 2018/03/08 06:00 [entrez] PHST- 2017/01/01 00:00 [pubmed] PHST- 2017/01/01 00:01 [medline] PHST- 2017/12/06 00:00 [pmc-release] AID - 10.1155/2017/4856412 [doi] PST - ppublish SO - Evid Based Complement Alternat Med. 2017;2017:4856412. doi: 10.1155/2017/4856412. Epub 2017 Dec 6.