PMID- 29515183
OWN - NLM
STAT- MEDLINE
DCOM- 20190918
LR  - 20200306
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 8
IP  - 1
DP  - 2018 Mar 7
TI  - Emergence of Different Recombinant Porcine Reproductive and Respiratory Syndrome 
      Viruses, China.
PG  - 4118
LID - 10.1038/s41598-018-22494-4 [doi]
LID - 4118
AB  - Epidemiological investigations were conducted on recently emerging porcine 
      reproductive and respiratory syndrome virus (PRRSV) strains in Shandong province 
      in 2014-2015. The proportion of the NADC30 strain identified by ORF7 sequence 
      alignment has been gradually increasing. Three emerging PRRSV strains were 
      successfully isolated, and the complete genomic sequences were determined. Our 
      results indicate the importance of recombinant strains in Shandong province, 
      China. There was a varied degree of recombination of two or three strains 
      (classical, HP-PRRSV and/or NADC30). Moreover, the recombination strains affected 
      the pathogenicity of newly emerged strains.
FAU - Liu, Yanyan
AU  - Liu Y
AD  - Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of 
      Animal Science and Veterinary Medicine, Shandong Academy of Agricultural 
      Sciences, Jinan, 250100, China.
AD  - School of Life Sciences, Shandong University, Jinan, 250100, China.
AD  - Biotechnology Research Center, Shandong Academy of Agricultural Sciences, Jinan, 
      250100, China.
FAU - Li, Jianda
AU  - Li J
AD  - Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of 
      Animal Science and Veterinary Medicine, Shandong Academy of Agricultural 
      Sciences, Jinan, 250100, China.
FAU - Yang, Jie
AU  - Yang J
AD  - Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of 
      Animal Science and Veterinary Medicine, Shandong Academy of Agricultural 
      Sciences, Jinan, 250100, China.
FAU - Zeng, Hao
AU  - Zeng H
AD  - Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of 
      Animal Science and Veterinary Medicine, Shandong Academy of Agricultural 
      Sciences, Jinan, 250100, China.
FAU - Guo, Lihui
AU  - Guo L
AD  - Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of 
      Animal Science and Veterinary Medicine, Shandong Academy of Agricultural 
      Sciences, Jinan, 250100, China.
FAU - Ren, Sufang
AU  - Ren S
AD  - Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of 
      Animal Science and Veterinary Medicine, Shandong Academy of Agricultural 
      Sciences, Jinan, 250100, China.
FAU - Sun, Wenbo
AU  - Sun W
AD  - Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of 
      Animal Science and Veterinary Medicine, Shandong Academy of Agricultural 
      Sciences, Jinan, 250100, China.
FAU - Chen, Zhi
AU  - Chen Z
AD  - Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of 
      Animal Science and Veterinary Medicine, Shandong Academy of Agricultural 
      Sciences, Jinan, 250100, China.
FAU - Cong, Xiaoyan
AU  - Cong X
AD  - Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of 
      Animal Science and Veterinary Medicine, Shandong Academy of Agricultural 
      Sciences, Jinan, 250100, China.
FAU - Shi, Jianli
AU  - Shi J
AD  - Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of 
      Animal Science and Veterinary Medicine, Shandong Academy of Agricultural 
      Sciences, Jinan, 250100, China.
FAU - Chen, Lei
AU  - Chen L
AD  - Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of 
      Animal Science and Veterinary Medicine, Shandong Academy of Agricultural 
      Sciences, Jinan, 250100, China.
FAU - Du, Yijun
AU  - Du Y
AD  - Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of 
      Animal Science and Veterinary Medicine, Shandong Academy of Agricultural 
      Sciences, Jinan, 250100, China.
AD  - School of Life Sciences, Shandong Normal University, Jinan, Jinan, 250014, China.
FAU - Li, Jun
AU  - Li J
AD  - Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of 
      Animal Science and Veterinary Medicine, Shandong Academy of Agricultural 
      Sciences, Jinan, 250100, China.
AD  - School of Life Sciences, Shandong Normal University, Jinan, Jinan, 250014, China.
FAU - Wang, Jinbao
AU  - Wang J
AD  - Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of 
      Animal Science and Veterinary Medicine, Shandong Academy of Agricultural 
      Sciences, Jinan, 250100, China. wangjb@saas.ac.cn.
AD  - School of Life Sciences, Shandong University, Jinan, 250100, China. 
      wangjb@saas.ac.cn.
AD  - School of Life Sciences, Shandong Normal University, Jinan, Jinan, 250014, China. 
      wangjb@saas.ac.cn.
FAU - Wu, Jiaqiang
AU  - Wu J
AD  - Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of 
      Animal Science and Veterinary Medicine, Shandong Academy of Agricultural 
      Sciences, Jinan, 250100, China. wujiaqiang2000@sina.com.
AD  - School of Life Sciences, Shandong University, Jinan, 250100, China. 
      wujiaqiang2000@sina.com.
AD  - School of Life Sciences, Shandong Normal University, Jinan, Jinan, 250014, China. 
      wujiaqiang2000@sina.com.
FAU - Yu, Jiang
AU  - Yu J
AD  - Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of 
      Animal Science and Veterinary Medicine, Shandong Academy of Agricultural 
      Sciences, Jinan, 250100, China. yujiang_2213@163.com.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180307
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
SB  - IM
EIN - Sci Rep. 2018 May 23;8(1):8215. PMID: 29795230
MH  - Animals
MH  - *Genome, Viral
MH  - *Phylogeny
MH  - Porcine Reproductive and Respiratory Syndrome/*genetics
MH  - Porcine respiratory and reproductive syndrome virus/*genetics/isolation & 
      purification
MH  - *Recombination, Genetic
MH  - Sequence Alignment
MH  - Swine/*virology
PMC - PMC5841431
COIS- The authors declare no competing interests.
EDAT- 2018/03/09 06:00
MHDA- 2019/09/19 06:00
PMCR- 2018/03/07
CRDT- 2018/03/09 06:00
PHST- 2017/10/09 00:00 [received]
PHST- 2018/02/22 00:00 [accepted]
PHST- 2018/03/09 06:00 [entrez]
PHST- 2018/03/09 06:00 [pubmed]
PHST- 2019/09/19 06:00 [medline]
PHST- 2018/03/07 00:00 [pmc-release]
AID - 10.1038/s41598-018-22494-4 [pii]
AID - 22494 [pii]
AID - 10.1038/s41598-018-22494-4 [doi]
PST - epublish
SO  - Sci Rep. 2018 Mar 7;8(1):4118. doi: 10.1038/s41598-018-22494-4.