PMID- 29520205
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220316
IS  - 1318-2099 (Print)
IS  - 1581-3207 (Electronic)
IS  - 1318-2099 (Linking)
VI  - 52
IP  - 1
DP  - 2018 Mar
TI  - Simultaneous Pure Laparoscopic Resection of Primary Colorectal Cancer and 
      Synchronous Liver Metastases: A Single Institution Experience with Propensity 
      Score Matching Analysis.
PG  - 42-53
LID - 10.1515/raon-2017-0047 [doi]
AB  - BACKGROUND: The aim of the study was to compare the outcome of pure laparoscopic 
      and open simultaneous resection of both the primary colorectal cancer and 
      synchronous colorectal liver metastases (SCLM). PATIENTS AND METHODS: From 2000 
      to 2016 all patients treated by simultaneous resection were assessed for entry in 
      this single center, clinically nonrandomized trial. A propensity score matching 
      was used to compare the laparoscopic group (LAP) to open surgery group (OPEN). 
      Primary endpoints were perioperative and oncologic outcomes. Secondary endpoints 
      were overall survival (OS) and disease-free survival (DFS). RESULTS: Of the 82 
      patients identified who underwent simultaneous liver resection for SCLM, 10 
      patients underwent LAP. All these consecutive patients from LAP were matched to 
      10 comparable OPEN. LAP reduced the length of hospital stay (P = 0.044) and solid 
      food oral intake was faster (P = 0.006) in this group. No patient undergoing the 
      laparoscopic procedure experienced conversion to the open technique. No 
      difference was observed in operative time, blood loss, transfusion rate, 
      narcotics requirement, clinical risk score, resection margin, R0 resections rate, 
      morbidity, mortality and incisional hernias rate. The two groups did not differ 
      significantly in terms of the 3-year OS rate (90 vs. 75%; P = 0.842) and DFS rate 
      (60 vs. 57%; P = 0.724). CONCLUSIONS: LAP reduced the length of hospital stay and 
      offers faster solid food oral intake. Comparable oncologic and survival outcomes 
      can be achieved. LAP is beneficial for well selected patients in high volume 
      centers with appropriate expertise.
FAU - Ivanecz, Arpad
AU  - Ivanecz A
AD  - Department of Abdominal and General Surgery, University Medical Center Maribor, 
      Maribor, Slovenia.
AD  - Department of Surgery, Faculty of Medicine, University of Maribor, Maribor, 
      Slovenia.
FAU - Krebs, Bojan
AU  - Krebs B
AD  - Department of Abdominal and General Surgery, University Medical Center Maribor, 
      Maribor, Slovenia.
AD  - Department of Surgery, Faculty of Medicine, University of Maribor, Maribor, 
      Slovenia.
FAU - Stozer, Andraz
AU  - Stozer A
AD  - Institute of Physiology, Faculty of Medicine, University of Maribor, Maribor, 
      Slovenia.
FAU - Jagric, Tomaz
AU  - Jagric T
AD  - Department of Abdominal and General Surgery, University Medical Center Maribor, 
      Maribor, Slovenia.
FAU - Plahuta, Irena
AU  - Plahuta I
AD  - Department of Abdominal and General Surgery, University Medical Center Maribor, 
      Maribor, Slovenia.
FAU - Potrc, Stojan
AU  - Potrc S
AD  - Department of Abdominal and General Surgery, University Medical Center Maribor, 
      Maribor, Slovenia.
AD  - Department of Surgery, Faculty of Medicine, University of Maribor, Maribor, 
      Slovenia.
LA  - eng
PT  - Journal Article
DEP - 20171101
PL  - Poland
TA  - Radiol Oncol
JT  - Radiology and oncology
JID - 9317213
PMC - PMC5839081
OTO - NOTNLM
OT  - colorectal cancer
OT  - colorectal resection
OT  - laparoscopy
OT  - liver resection
OT  - synchronous liver metastases
COIS- Disclosure: No potential conflicts of interest were disclosed.
EDAT- 2018/03/10 06:00
MHDA- 2018/03/10 06:01
PMCR- 2018/03/01
CRDT- 2018/03/10 06:00
PHST- 2017/09/08 00:00 [received]
PHST- 2017/10/08 00:00 [accepted]
PHST- 2018/03/10 06:00 [entrez]
PHST- 2018/03/10 06:00 [pubmed]
PHST- 2018/03/10 06:01 [medline]
PHST- 2018/03/01 00:00 [pmc-release]
AID - raon-2017-0047 [pii]
AID - 10.1515/raon-2017-0047 [doi]
PST - epublish
SO  - Radiol Oncol. 2017 Nov 1;52(1):42-53. doi: 10.1515/raon-2017-0047. eCollection 
      2018 Mar.