PMID- 29521816
OWN - NLM
STAT- MEDLINE
DCOM- 20220217
LR  - 20230930
IS  - 1549-8425 (Electronic)
IS  - 1549-8417 (Linking)
VI  - 17
IP  - 8
DP  - 2021 Dec 1
TI  - Incidence and Causes of Adverse Events in Diagnostic Radiological Studies 
      Requiring Anesthesia in the Wake-Up Safe Registry.
PG  - e1261-e1266
LID - 10.1097/PTS.0000000000000469 [doi]
AB  - OBJECTIVES: General anesthesia or sedation can facilitate the completion of 
      diagnostic radiological studies in children. We evaluated the incidence, 
      predictors, and causes of adverse events (AEs) when general anesthesia is 
      provided for diagnostic radiological imaging. METHODS: Deidentified data from 24 
      pediatric tertiary care hospitals participating in the Wake-Up Safe registry 
      during 2010-2015 were obtained for analysis. Children 18 years or younger 
      receiving general anesthesia for radiological procedures were identified using 
      Current Procedural Terminology codes, and reported AEs were analyzed if they were 
      associated with anesthetic care at magnetic resonance imaging or computed 
      tomography locations. Logistic regression was used to determine predictors of AE 
      occurrence in cases with complete covariate data. RESULTS: We identified 175,486 
      anesthetics for diagnostic radiological exams, compared with 83 AEs in magnetic 
      resonance imaging or computed tomography locations (AE incidence of 0.05%). In 
      multivariable analysis, AEs were more likely among patients with American Society 
      of Anesthesiologists physical status IV compared with American Society of 
      Anesthesiologists physical status I patients (adjusted odds ratio, 8.9; 95% 
      confidence interval, 2.8-28.0; P < 0.001). Twenty-three AEs resulted in harm to 
      the patient, whereas 32 AEs required unplanned hospital or intensive care unit 
      admission. Anesthetic complications or issues were the most common cause of AEs 
      (n = 52). CONCLUSIONS: Anesthesia provided for pediatric radiological studies is 
      very safe and with an overall low AE incidence. The contribution of anesthetic 
      complications to reported AEs suggests opportunities for further process 
      improvement in this setting.
CI  - Copyright (c) 2018 Wolters Kluwer Health, Inc. All rights reserved.
FAU - Khawaja, Asad A
AU  - Khawaja AA
FAU - Tumin, Dmitry
AU  - Tumin D
FAU - Beltran, Ralph J
AU  - Beltran RJ
FAU - Tobias, Joseph D
AU  - Tobias JD
FAU - Uffman, Joshua C
AU  - Uffman JC
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Patient Saf
JT  - Journal of patient safety
JID - 101233393
SB  - IM
MH  - *Anesthesia/adverse effects
MH  - Child
MH  - Hospitalization
MH  - Humans
MH  - Incidence
MH  - Registries
MH  - Risk Factors
COIS- The authors disclose no conflict of interest.
EDAT- 2018/03/10 06:00
MHDA- 2022/02/19 06:00
CRDT- 2018/03/10 06:00
PHST- 2018/03/10 06:00 [pubmed]
PHST- 2022/02/19 06:00 [medline]
PHST- 2018/03/10 06:00 [entrez]
AID - 01209203-202112000-00082 [pii]
AID - 10.1097/PTS.0000000000000469 [doi]
PST - ppublish
SO  - J Patient Saf. 2021 Dec 1;17(8):e1261-e1266. doi: 10.1097/PTS.0000000000000469.