PMID- 29531881
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 10
IP  - 1
DP  - 2018 Jan 5
TI  - Association of Hypertrophic Obstructive Cardiomyopathy with Rheumatoid Arthritis.
PG  - e2028
LID - 10.7759/cureus.2028 [doi]
LID - e2028
AB  - Our article refers to a 50-year-old woman with previously diagnosed rheumatoid 
      arthritis (RA) who presented with symptoms of dyspnea on exertion and dizziness. 
      An echocardiogram revealed a 17-mm asymmetric interventricular septum hypertrophy 
      and systolic anterior motion of the anterior mitral valve leaflet. Association of 
      hypertrophic obstructive cardiomyopathy (HCM) with connective tissue diseases has 
      been well documented. For RA the human leukocyte antigen (HLA) system, 
      particularly HLA-DR4, may possibly be a link between the two entities, as it is 
      associated with both RA and HCM. Therefore, a patient with RA and suggestive 
      history should be investigated for cardiac involvement. Further studies are 
      needed to elucidate a more accurate association between the above diseases.
FAU - Dawood, Mustafa
AU  - Dawood M
AD  - General Internal Medicine, Greater Baltimore Medical Center.
FAU - Lateef, Noman
AU  - Lateef N
AD  - Department of Medicine, Dow University of Health Sciences (DUHS), Karachi, 
      Pakistan.
FAU - Tauseef, Abubakar
AU  - Tauseef A
AD  - Department of Medicine, Dow University of Health Sciences (DUHS), Karachi, 
      Pakistan.
FAU - Patel, Janki
AU  - Patel J
AD  - General Internal Medicine, Greater Baltimore Medical Center.
LA  - eng
PT  - Case Reports
DEP - 20180105
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC5837261
OTO - NOTNLM
OT  - autoimmune diseases
OT  - echocardiography
OT  - hla-dr antigens
OT  - hypertrophic obstructive cardiomyopathy
OT  - rheumatoid arthritis
COIS- The authors have declared that no competing interests exist.
EDAT- 2018/03/14 06:00
MHDA- 2018/03/14 06:01
PMCR- 2018/01/05
CRDT- 2018/03/14 06:00
PHST- 2018/03/14 06:00 [entrez]
PHST- 2018/03/14 06:00 [pubmed]
PHST- 2018/03/14 06:01 [medline]
PHST- 2018/01/05 00:00 [pmc-release]
AID - 10.7759/cureus.2028 [doi]
PST - epublish
SO  - Cureus. 2018 Jan 5;10(1):e2028. doi: 10.7759/cureus.2028.