PMID- 29536890 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20191120 IS - 2194-802X (Electronic) IS - 2194-802X (Linking) VI - 3 IP - 2 DP - 2016 Jun 1 TI - Mobile phone exposure influences some erythrocytes parameters in vitro. A novel source of preanalytical variability? PG - 75-79 LID - /j/dx.2016.3.issue-2/dx-2016-0010/dx-2016-0010.xml [pii] LID - 10.1515/dx-2016-0010 [doi] AB - BACKGROUND: The effect of radiofrequency exposure on human health and health care equipment is a matter of ongoing debate. This study was planned to investigate the influence of radiofrequency (RF) waves emitted by a commercial mobile phone on red blood cells (RBC) in vitro. METHODS: The study population consisted of 16 ostensibly healthy volunteers. Two whole blood specimens were collected from each volunteer. One sample was placed in a plastic rack, 1 cm distant from the chassis of a commercial mobile phone which was activated by a remote phone call lasting 30 min. The other blood sample was placed in another plastic rack, but was kept distant from any type of RF source. The main RBC parameters including RBC count, hematocrit (Ht), hemoglobin, mean corpuscular platelet volume (MPV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC) and RBC distribution width (RDW-CV) were assessed with an Advia 2120. RESULTS: The exposure of whole blood to the mobile phone call significantly increased Ht, hemoglobin, MCV and MCH, whereas the RBC count, MCHC and RDW-CV remained unchanged. A significant correlation was observed between variation of Ht and those of hemoglobin (p=0.008), MCV (p=0.009) or MCH (p=0.037), as well as between hemoglobin and MCV (p=0.048). Increased values were found in 13/16 (81%) samples for both Ht and hemoglobin, 14/16 (88%) samples for MCH and 16/16 (100%) samples for MCV. CONCLUSIONS: These results suggest that close mobile phone exposure may be an unappreciated and possibly underestimated cause of preanalytical bias in RBC testing. FAU - Danese, Elisa AU - Danese E AD - 1Section of Clinical Biochemistry, University of Verona, Verona, Italy. FAU - Lippi, Giuseppe AU - Lippi G AUID- ORCID: 0000-0001-9523-9054 AD - 1Section of Clinical Biochemistry, University of Verona, Verona, Italy. FAU - Brocco, Giorgio AU - Brocco G AD - 1Section of Clinical Biochemistry, University of Verona, Verona, Italy. FAU - Montagnana, Martina AU - Montagnana M AD - 1Section of Clinical Biochemistry, University of Verona, Verona, Italy. FAU - Salvagno, Gian Luca AU - Salvagno GL AD - 1Section of Clinical Biochemistry, University of Verona, Verona, Italy. LA - eng PT - Journal Article PL - Germany TA - Diagnosis (Berl) JT - Diagnosis (Berlin, Germany) JID - 101654734 OTO - NOTNLM OT - erythrocytes OT - hemoglobin OT - interference OT - mobile phone OT - radiofrequency OT - red blood cells EDAT- 2016/06/01 00:00 MHDA- 2016/06/01 00:01 CRDT- 2018/03/15 06:00 PHST- 2016/03/21 00:00 [received] PHST- 2016/03/30 00:00 [accepted] PHST- 2018/03/15 06:00 [entrez] PHST- 2016/06/01 00:00 [pubmed] PHST- 2016/06/01 00:01 [medline] AID - /j/dx.2016.3.issue-2/dx-2016-0010/dx-2016-0010.xml [pii] AID - 10.1515/dx-2016-0010 [doi] PST - ppublish SO - Diagnosis (Berl). 2016 Jun 1;3(2):75-79. doi: 10.1515/dx-2016-0010.