PMID- 29536903 OWN - NLM STAT- MEDLINE DCOM- 20180529 LR - 20181202 IS - 2194-802X (Electronic) IS - 2194-802X (Linking) VI - 3 IP - 4 DP - 2016 Dec 1 TI - Prehospital diagnosis of patients with acute myocardial infarction. PG - 155-166 LID - /j/dx.2016.3.issue-4/dx-2016-0021/dx-2016-0021.xml [pii] LID - 10.1515/dx-2016-0021 [doi] AB - Primary percutaneous intervention (PPCI) is the preferred treatment in patients with ST elevation myocardial infarction (STEMI) if this can be performed in a timely manner. The 2012 ESC Guidelines on management of AMI in patients presenting with ST-segment elevation advice that PPCI should be performed within 120 min of first medical contact. Prehospital diagnosis of patients with STEMI is performed to save time and make PPCI available to the majority of patients. Although diagnosing patients with STEMI is usually easy, there are important pitfalls and patients with STEMI are missed on occasion. In addition, it is well know that patients without ST elevation may also have a high-risk cardiac condition. The 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation stress the importance of urgent CAG in patients with high-risk non ST-segment elevation myocardial infarction (NSTEMI). Unfortunately, these patients are difficult to diagnose in the acute phase and important time may be spend establishing the correct diagnosis. Prehospital biomarker measurement has emerged as a method to gain important additional information. We review the evidence on prehospital diagnosis of patients with STEMI and, In addition, we present the current knowledge on the new diagnostic methods that could have a future role in prehospital rule-in and rule-out of cardiac disease. FAU - Stengaard, Carsten AU - Stengaard C AD - 1Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark. FAU - Sorensen, Jacob Thorsted AU - Sorensen JT AD - 1Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark. FAU - Rasmussen, Martin Bohme AU - Rasmussen MB AD - 1Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark. FAU - Botker, Morten Thingemann AU - Botker MT AD - 2Research and Development, Prehospital Emergency Medical Services, Central Denmark Region, Aarhus, Denmark. FAU - Pedersen, Claus Kjaer AU - Pedersen CK AD - 1Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark. FAU - Terkelsen, Christian Juhl AU - Terkelsen CJ AD - 1Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review PL - Germany TA - Diagnosis (Berl) JT - Diagnosis (Berlin, Germany) JID - 101654734 RN - 0 (Biomarkers) RN - 0 (Troponin) SB - IM MH - Ambulances/standards MH - Biomarkers/blood MH - *Early Diagnosis MH - Electrocardiography/methods MH - Emergency Medical Services/*standards MH - Humans MH - Myocardial Infarction/*diagnosis/epidemiology/mortality MH - Percutaneous Coronary Intervention/methods MH - Point-of-Care Systems/standards MH - ST Elevation Myocardial Infarction/*diagnosis/mortality/physiopathology/therapy MH - Telemedicine/statistics & numerical data MH - Time Factors MH - Time-to-Treatment MH - Troponin/blood OTO - NOTNLM OT - ST-segment elevation myocardial infarction OT - ambulances OT - cardiac troponin OT - early diagnosis OT - electrocardiography OT - non ST-segment myocardial infarction OT - point-of-care systems OT - telemedicine EDAT- 2016/12/01 00:00 MHDA- 2018/05/31 06:00 CRDT- 2018/03/15 06:00 PHST- 2016/06/29 00:00 [received] PHST- 2016/11/01 00:00 [accepted] PHST- 2018/03/15 06:00 [entrez] PHST- 2016/12/01 00:00 [pubmed] PHST- 2018/05/31 06:00 [medline] AID - /j/dx.2016.3.issue-4/dx-2016-0021/dx-2016-0021.xml [pii] AID - 10.1515/dx-2016-0021 [doi] PST - ppublish SO - Diagnosis (Berl). 2016 Dec 1;3(4):155-166. doi: 10.1515/dx-2016-0021.