PMID- 29540881 OWN - NLM STAT- MEDLINE DCOM- 20191021 LR - 20191022 IS - 0030-9982 (Print) IS - 0030-9982 (Linking) VI - 68 IP - 3 DP - 2018 Mar TI - Harmful consequences of specific substances on the oral health. PG - 437-443 AB - Numerous substances may have an adverse influence on the oral region by virtue of their potentially harmful effects. Dental practitioners are often the first to see these effects in the head and neck region. Knowledge of the damaging consequences of agents such as alcohol, tobacco, areca nut, medications, alcohol-containing mouthwashes, dental devices and materials can assist the practitioners in clinical decision-making and accurate diagnosis of associated lesions. More importantly, timely diagnosis and prompt reporting of such harmful effects improve the quality of care. Such knowledge may also help in patient's education for the avoidance of associated adverse effects (AEs). Consequently, a thorough acquaintance of AEs will consolidate the distinct role of medical and oral health practitioners in safeguarding the patients' oral and systemic well-being. This article was planned to review the harmful consequences of specific substances on the oral health. Traditionally, the emphasis of review articles has been on reviewing the harmful effects of a single entity on oral health. This review is unique in the sense that it comprehensively and collectively focussed on the harmful effects on the oral health of addictive and illicit substances (alcohol, betel nut), medications, alcohol-containing mouthwashes, medications and dental materials. FAU - Shaikh, Sameer AU - Shaikh S AD - Department of Oral Diagnosis & Oral Medicine, College of Dentistry, University of Ha'il, Ha'il, Saudi Arabia. FAU - Aljanakh, Mohammad AU - Aljanakh M AD - Department of Restorative Dentistry, College of Dentistry, University of Ha'il, Ha'il, Saudi Arabia. FAU - Al Ibrahim, Ibrahim Khalil AU - Al Ibrahim IK AD - College of Dentistry, University of Ha'il, Ha'il, Saudi Arabia. FAU - Memon, Mohammad Sohail AU - Memon MS AD - Faculty of Dentistry, The University of Sydney, Westmead, NSW, Australia. LA - eng PT - Journal Article PT - Review PL - Pakistan TA - J Pak Med Assoc JT - JPMA. The Journal of the Pakistan Medical Association JID - 7501162 RN - 0 (Dental Materials) RN - 0 (Mouthwashes) SB - IM MH - Alcohol Drinking/*adverse effects MH - Areca/*adverse effects MH - Candidiasis, Oral/etiology MH - Dental Materials/*adverse effects MH - Drug-Related Side Effects and Adverse Reactions/*etiology MH - Fibrosis/etiology MH - Gingival Overgrowth/etiology MH - Humans MH - Keratosis/etiology MH - Leukoplakia, Oral/etiology MH - Mouth Diseases/*etiology MH - Mouth Mucosa MH - Mouthwashes/*adverse effects MH - Oral Ulcer/etiology MH - Taste Disorders/etiology MH - Tobacco Use/*adverse effects OTO - NOTNLM OT - Oral health, Adverse effects, Alcohol, Tobacco, Areca (betel) nut, Alcohol-containing mouthwashes, Medications, Dental materials and devices. EDAT- 2018/03/16 06:00 MHDA- 2019/10/23 06:00 CRDT- 2018/03/16 06:00 PHST- 2018/03/16 06:00 [entrez] PHST- 2018/03/16 06:00 [pubmed] PHST- 2019/10/23 06:00 [medline] AID - 8609 [pii] PST - ppublish SO - J Pak Med Assoc. 2018 Mar;68(3):437-443.