PMID- 29544516
OWN - NLM
STAT- MEDLINE
DCOM- 20180904
LR  - 20181114
IS  - 1749-799X (Electronic)
IS  - 1749-799X (Linking)
VI  - 13
IP  - 1
DP  - 2018 Mar 15
TI  - A comparison of clinical- and patient-reported outcomes of the cemented ATTUNE 
      and PFC sigma fixed bearing cruciate sacrificing knee systems in patients who 
      underwent total knee replacement with both prostheses in opposite knees.
PG  - 54
LID - 10.1186/s13018-018-0757-6 [doi]
LID - 54
AB  - BACKGROUND: The ATTUNE Knee by DePuy Synthes was introduced in 2013. It is 
      designed to provide better range of motion and address patient-reported 
      instability. The PFC Sigma Knee, an earlier prosthesis by DePuy Synthes, is a 
      common knee replacement with a strong clinical track record. Our aim is to 
      compare the outcomes after primary total knee replacement for end-stage knee 
      osteoarthritis of the PFC and ATTUNE knee systems in 21 patients who each have 
      prosthesis in opposite knees using WOMAC, Oxford Knee and SF-12 scores and 
      evaluation of range of motion. METHODS: A review was carried out on 21 patients 
      who underwent primary total knee replacement with both the ATTUNE and PFC knee 
      systems. These were staged operations performed in the same institution and by 
      the same surgeon. All cases were followed up for a minimum of 6 months. WOMAC, 
      Oxford Knee and SF-12 scores, as well as knee range of motion were recorded 
      preoperatively and at 6 months postoperatively. RESULTS: There was a significant 
      difference in pre- to 6-month post-operative outcomes in PFC and ATTUNE groups 
      with regard to improvement in range of motion (10 degrees  +/- 8 and 13 degrees  +/- 11, 
      respectively). There was also a significant improvement in WOMAC scores (PFC 
      group) and Oxford Knee Scores (ATTUNE group) (8.9 +/- 7.7 and 12.1 +/- 8.4, 
      respectively). There was a significant improvement in SF-12 Score in both groups 
      (10.1 +/- 9.3 for PFC and 15.8 +/- 13.3 for ATTUNE). The minimum clinically important 
      difference (MCID) in scoring systems at 6 months was reached by 6 patients in the 
      PFC group and 12 in the ATTUNE group. CONCLUSION: A significant difference was 
      demonstrated in clinical outcome at 6 months postoperatively between PFC and 
      ATTUNE knee systems in patients who underwent total knee arthroplasty with both 
      prostheses. Superior results were recorded for the ATTUNE knee system.
FAU - Carey, Brian W
AU  - Carey BW
AUID- ORCID: 0000-0002-6584-8032
AD  - Cork University Hospital Group, Wilton, Cork, Ireland. bcarey@umail.ucc.ie.
FAU - Harty, James
AU  - Harty J
AD  - MRCSI FRCSI (Trauma and Orthopaedics) Consultant Orthopaedic Surgeon, Cork 
      University Hospital Group, Cork, Ireland.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20180315
PL  - England
TA  - J Orthop Surg Res
JT  - Journal of orthopaedic surgery and research
JID - 101265112
SB  - IM
MH  - Aged
MH  - Arthroplasty, Replacement, Knee/*instrumentation/methods
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Knee Joint/physiopathology/surgery
MH  - *Knee Prosthesis
MH  - Male
MH  - Middle Aged
MH  - Osteoarthritis, Knee/*surgery
MH  - Patient Reported Outcome Measures
MH  - Prosthesis Design
MH  - Range of Motion, Articular
MH  - Retrospective Studies
MH  - Severity of Illness Index
MH  - Treatment Outcome
PMC - PMC5856217
OTO - NOTNLM
OT  - ATTUNE
OT  - PFC
OT  - Patient-reported outcome measures
OT  - Range of movement
OT  - Total knee arthroplasty
COIS- AUTHORS' INFORMATION: JH was the sole orthopaedic surgeon who performed total 
      knee replacement surgery on the patients included in this study. ETHICS APPROVAL 
      AND CONSENT TO PARTICIPATE: All procedures performed in studies involving human 
      participants were in accordance with the ethical standards of the institutional 
      and/or national research committee and with the 1964 Helsinki declaration and its 
      later amendments or comparable ethical standards. For this type of study, formal 
      consent is not required. Ethical approval was granted from the SIVUH hospital 
      ethics committee as well the Clinical Research Ethics Committee (CREC), Cork. 
      CONSENT FOR PUBLICATION: Not applicable COMPETING INTERESTS: The authors declare 
      that they have no competing interests. PUBLISHER'S NOTE: Springer Nature remains 
      neutral with regard to jurisdictional claims in published maps and institutional 
      affiliations.
EDAT- 2018/03/17 06:00
MHDA- 2018/09/05 06:00
PMCR- 2018/03/15
CRDT- 2018/03/17 06:00
PHST- 2017/06/19 00:00 [received]
PHST- 2018/03/07 00:00 [accepted]
PHST- 2018/03/17 06:00 [entrez]
PHST- 2018/03/17 06:00 [pubmed]
PHST- 2018/09/05 06:00 [medline]
PHST- 2018/03/15 00:00 [pmc-release]
AID - 10.1186/s13018-018-0757-6 [pii]
AID - 757 [pii]
AID - 10.1186/s13018-018-0757-6 [doi]
PST - epublish
SO  - J Orthop Surg Res. 2018 Mar 15;13(1):54. doi: 10.1186/s13018-018-0757-6.