PMID- 29551663
OWN - NLM
STAT- MEDLINE
DCOM- 20181105
LR  - 20181105
IS  - 1876-861X (Electronic)
IS  - 1876-861X (Linking)
VI  - 12
IP  - 4
DP  - 2018 Jul-Aug
TI  - High-pitch versus sequential mode for coronary calcium in individuals with a high 
      heart rate: Potential for dose reduction.
PG  - 298-304
LID - S1934-5925(18)30047-9 [pii]
LID - 10.1016/j.jcct.2018.02.005 [doi]
AB  - BACKGROUND: To determine the impact of high-pitch spiral acquisition on radiation 
      dose and cardiovascular disease (CVD) risk stratification by coronary artery 
      calcium (CAC) assessment with computed tomography in individuals with a high 
      heart rate. METHODS: Of the ROBINSCA trial, 1990 participants with regular rhythm 
      and heart rates >65 beats per minute (bpm) were included. As reference, 390 
      participants with regular heart rates </=65 bpm were used. All participants 
      underwent prospectively electrocardiographically(ECG)-triggered imaging of the 
      coronary arteries using dual source CT at 120 kVp, 80 ref mAs using both 
      high-pitch spiral mode and sequential mode. Radiation dose, Agatston score, 
      number of positive scores, as well as median absolute difference of the Agatston 
      score were determined and participants were stratified into CVD risk categories. 
      RESULTS: A similar percentage of participants with low heart rates and high heart 
      rates had a positive CAC score in data sets acquired in high-pitch spiral (low 
      heart rate: 57.7%, high heart rate: 55.8%) and sequential mode (58.0%, 54.7%, 
      p = n.s.). The median absolute difference in Agatston scores between acquisition 
      modes was 14.2% and 9.2%, for the high and low heart rate groups, respectively. 
      Excellent agreement for risk categorization between the two data acquisition 
      modes was found for the high (kappa = 0.927) and low (kappa = 0.946) heart rate groups. 
      Radiation dose was 48% lower for high-pitch spiral versus sequential 
      acquisitions. CONCLUSION: Radiation dose for the quantification of coronary 
      calcium can be reduced by 48% when using the high-pitch spiral acquisition mode 
      compared to the sequential mode in participants with a regular high heart rate. 
      CVD risk stratification agreement between the two modes of data acquisition is 
      excellent.
CI  - Copyright (c) 2018 Society of Cardiovascular Computed Tomography. Published by 
      Elsevier Inc. All rights reserved.
FAU - Vonder, Marleen
AU  - Vonder M
AD  - University of Groningen, University Medical Center Groningen, Center for Medical 
      Imaging North-East Netherlands (CMI-NEN), Groningen, The Netherlands. Electronic 
      address: m.vonder@umcg.nl.
FAU - Vliegenthart, Rozemarijn
AU  - Vliegenthart R
AD  - University of Groningen, University Medical Center Groningen, Center for Medical 
      Imaging North-East Netherlands (CMI-NEN), Groningen, The Netherlands. Electronic 
      address: r.vliegenthart@umcg.nl.
FAU - Kaatee, Merel A
AU  - Kaatee MA
AD  - University of Groningen, University Medical Center Groningen, Center for Medical 
      Imaging North-East Netherlands (CMI-NEN), Groningen, The Netherlands. Electronic 
      address: m.a.kaatee@umcg.nl.
FAU - van der Aalst, Carlijn M
AU  - van der Aalst CM
AD  - Erasmus MC, Dept. of Public Health, Rotterdam, The Netherlands. Electronic 
      address: c.vanderaalst@erasmusmc.nl.
FAU - van Ooijen, Peter M A
AU  - van Ooijen PMA
AD  - University of Groningen, University Medical Center Groningen, Center for Medical 
      Imaging North-East Netherlands (CMI-NEN), Groningen, The Netherlands. Electronic 
      address: p.m.a.van.ooijen@umcg.nl.
FAU - de Bock, Geertruida H
AU  - de Bock GH
AD  - University of Groningen, University Medical Center Groningen, Department of 
      Epidemiology, Groningen, The Netherlands. Electronic address: 
      g.h.de.bock@umcg.nl.
FAU - Gratama, Jan Willem
AU  - Gratama JW
AD  - University of Groningen, University Medical Center Groningen, Center for Medical 
      Imaging North-East Netherlands (CMI-NEN), Groningen, The Netherlands; Gelre 
      Ziekenhuizen, Dept. of Radiology, Apeldoorn, The Netherlands. Electronic address: 
      j.w.gratama@gelre.nl.
FAU - Kuijpers, Dirkjan
AU  - Kuijpers D
AD  - University of Groningen, University Medical Center Groningen, Center for Medical 
      Imaging North-East Netherlands (CMI-NEN), Groningen, The Netherlands; 
      HMC-Bronovo, Dept. of Radiology, The Hague, The Netherlands. Electronic address: 
      t.kuijpers@haaglandenmc.nl.
FAU - de Koning, Harry J
AU  - de Koning HJ
AD  - Erasmus MC, Dept. of Public Health, Rotterdam, The Netherlands. Electronic 
      address: h.dekoning@erasmusmc.nl.
FAU - Oudkerk, Matthijs
AU  - Oudkerk M
AD  - University of Groningen, University Medical Center Groningen, Center for Medical 
      Imaging North-East Netherlands (CMI-NEN), Groningen, The Netherlands. Electronic 
      address: m.oudkerk@umcg.nl.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20180301
PL  - United States
TA  - J Cardiovasc Comput Tomogr
JT  - Journal of cardiovascular computed tomography
JID - 101308347
SB  - IM
MH  - Aged
MH  - *Cardiac-Gated Imaging Techniques/adverse effects
MH  - Computed Tomography Angiography/adverse effects/*methods
MH  - Coronary Angiography/adverse effects/*methods
MH  - Coronary Artery Disease/*diagnostic imaging/physiopathology
MH  - Electrocardiography
MH  - Female
MH  - *Heart Rate
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Predictive Value of Tests
MH  - *Radiation Dosage
MH  - Radiation Exposure/adverse effects/*prevention & control
MH  - Randomized Controlled Trials as Topic
MH  - Reproducibility of Results
MH  - Risk Factors
MH  - Severity of Illness Index
MH  - Tomography, Spiral Computed/adverse effects/*methods
MH  - Vascular Calcification/*diagnostic imaging/physiopathology
OTO - NOTNLM
OT  - Cardiovascular diseases
OT  - Coronary vessels
OT  - Heart rate
OT  - Tomography
OT  - X-ray computed
EDAT- 2018/03/20 06:00
MHDA- 2018/11/06 06:00
CRDT- 2018/03/20 06:00
PHST- 2017/11/06 00:00 [received]
PHST- 2018/01/09 00:00 [revised]
PHST- 2018/02/26 00:00 [accepted]
PHST- 2018/03/20 06:00 [pubmed]
PHST- 2018/11/06 06:00 [medline]
PHST- 2018/03/20 06:00 [entrez]
AID - S1934-5925(18)30047-9 [pii]
AID - 10.1016/j.jcct.2018.02.005 [doi]
PST - ppublish
SO  - J Cardiovasc Comput Tomogr. 2018 Jul-Aug;12(4):298-304. doi: 
      10.1016/j.jcct.2018.02.005. Epub 2018 Mar 1.