PMID- 29551876 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20191120 IS - 1058-9813 (Print) IS - 1058-9813 (Linking) VI - 39 IP - 2 Pt B DP - 2015 Dec TI - Mustard baffle obstruction and leak - How successful are percutaneous interventions in adults? PG - 157-163 LID - 10.1016/j.ppedcard.2015.10.018 [doi] AB - Atrial switch operations for D-Transposition of the great arteries (D-TGA) were performed until the late 20th century. These patients have substantial rates of re-operation, particularly for baffle related complications. This study sought to analyze the efficacy of percutaneous transcatheter intervention (PTI) for baffle leak and/or stenosis in adult atrial switch patients. Adult patients with a prior atrial switch operation who underwent heart catheterization (2002-2014) at a tertiary adult congenital heart disease referral center were retrospectively analyzed. In 58 adults (30 +/- 8 years, 75% men, 14% New York Heart Association (NYHA) functional class >/=2) who underwent 79 catheterizations, PTI was attempted in 50 (baffle leak (n = 10, 20%), stenosis (n = 27, 54%), or both (n = 13, 26%)). PTI was successful in 45 and 5 were referred for surgery due to complex anatomy. A total of 40 bare metal stents, 18 covered stents, 16 occlusion devices, 2 angioplasties, and 1 endovascular graft were deployed. In isolated stenosis, there was improvement in NYHA functional class after PTI (8 vs. 0 patients were NYHA FC > 2, p = 0.004), which was matched by improvement in maximal oxygen consumption on exercise testing (VO(2)) (25.1 +/- 5.4 mL/kg/min vs. 27.9 +/- 9 mL/kg/min, p = 0.03). There were no procedure-related deaths or emergent surgeries in this cohort. This single-center cohort is the largest reported series of adult atrial switch operation patients who have undergone PTI for baffle stenosis and/or leak. We demonstrate that PTI with an expert multi-disciplinary team is a safe and effective alternative to surgery in adult patients with an atrial switch operation. FAU - Bradley, Elisa A AU - Bradley EA AD - Nationwide Children's Hospital Department of Pediatric Medicine & The Ohio State University Department of Internal Medicine, Columbus, OH, USA. FAU - Cai, Amanda AU - Cai A AD - Nationwide Children's Hospital Department of Pediatric Medicine & The Ohio State University Department of Internal Medicine, Columbus, OH, USA. FAU - Cheatham, Sharon L AU - Cheatham SL AD - Nationwide Children's Hospital Department of Pediatric Medicine & The Ohio State University Department of Internal Medicine, Columbus, OH, USA. FAU - Chisolm, Joanne AU - Chisolm J AD - Nationwide Children's Hospital Department of Pediatric Medicine & The Ohio State University Department of Internal Medicine, Columbus, OH, USA. FAU - Sisk, Tracey AU - Sisk T AD - Nationwide Children's Hospital Department of Pediatric Medicine & The Ohio State University Department of Internal Medicine, Columbus, OH, USA. FAU - Daniels, Curt J AU - Daniels CJ AD - Nationwide Children's Hospital Department of Pediatric Medicine & The Ohio State University Department of Internal Medicine, Columbus, OH, USA. FAU - Cheatham, John P AU - Cheatham JP AD - Nationwide Children's Hospital Department of Pediatric Medicine & The Ohio State University Department of Internal Medicine, Columbus, OH, USA. LA - eng GR - L30 HL138804/HL/NHLBI NIH HHS/United States PT - Journal Article DEP - 20151022 PL - Netherlands TA - Prog Pediatr Cardiol JT - Progress in pediatric cardiology JID - 9209539 PMC - PMC5856449 MID - NIHMS944248 OTO - NOTNLM OT - Baffle leak OT - Baffle stenosis OT - D-transposition of the great arteries OT - Mustard repair OT - Percutaneous intervention EDAT- 2015/12/01 00:00 MHDA- 2015/12/01 00:01 PMCR- 2018/03/16 CRDT- 2018/03/20 06:00 PHST- 2018/03/20 06:00 [entrez] PHST- 2015/12/01 00:00 [pubmed] PHST- 2015/12/01 00:01 [medline] PHST- 2018/03/16 00:00 [pmc-release] AID - 10.1016/j.ppedcard.2015.10.018 [doi] PST - ppublish SO - Prog Pediatr Cardiol. 2015 Dec;39(2 Pt B):157-163. doi: 10.1016/j.ppedcard.2015.10.018. Epub 2015 Oct 22.