PMID- 29559709
OWN - NLM
STAT- MEDLINE
DCOM- 20191104
LR  - 20191104
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 8
IP  - 1
DP  - 2018 Mar 20
TI  - Laparoscopic Organopexy with Non-mesh Genital (LONG) Suspension: A Novel Uterine 
      Preservation Procedure for the Treatment of Apical Prolapse.
PG  - 4872
LID - 10.1038/s41598-018-23285-7 [doi]
LID - 4872
AB  - To assess whether our novel uterus-sparing procedure- laparoscopic organopexy 
      with non-mesh genital(LONG) suspension is an effective, safe, and timesaving 
      surgery for the treatment of apical prolapse. Forty consecutive women with main 
      uterine prolapse stage II or greater defined by the POP quantification(POP-Q) 
      staging system were referred for LONG procedures at our hospitals. Clinical 
      evaluations before and 6 months after surgery included pelvic examination, 
      urodynamic study, and a personal interview to evaluate urinary and sexual 
      symptoms with overactive bladder symptom score(OABSS), the short forms of 
      Urogenital Distress Inventory(UDI-6) and Incontinence Impact 
      Questionnaire(IIQ-7), and the Female Sexual Function Index(FSFI). After follow-up 
      time of 12 to 30 months, anatomical cure rate was 85%(34/40), and the success 
      rates for apical, anterior, and posterior vaginal prolapse were 95%(38/40), 
      85%(34/40), and 97.5%(39/40), respectively. Six recurrences of anterior vaginal 
      wall all suffered from significant cystocele (stage3; Ba>+1) preoperatively. The 
      average operative time was 73.1 +/- 30.8 minutes. One bladder injury occurred and 
      was recognized during surgery. The dyspareunia domain and total FSFI scores of 
      the twelve sexually-active premenopausal women improved postoperatively in a 
      significant manner (P < 0.05). The results of our study suggest that LONG 
      suspension is an effective and safe uterus-sparing surgery for the treatment of 
      apical prolapse.
FAU - Long, Cheng-Yu
AU  - Long CY
AD  - Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, 
      Kaohsiung Medical University, Kaohsiung, Taiwan.
AD  - Department of Obstetrics and Gynecology, Kaohsiung Municipal Hsiao-Kang Hospital, 
      Kaohsiung Medical University, Kaohsiung, Taiwan.
AD  - Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical 
      University, Kaohsiung, Taiwan.
FAU - Wang, Chiu-Lin
AU  - Wang CL
AD  - Department of Obstetrics and Gynecology, Kaohsiung Municipal Hsiao-Kang Hospital, 
      Kaohsiung Medical University, Kaohsiung, Taiwan.
AD  - Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical 
      University, Kaohsiung, Taiwan.
FAU - Ker, Chin-Ru
AU  - Ker CR
AD  - Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, 
      Kaohsiung Medical University, Kaohsiung, Taiwan.
FAU - Juan, Yung-Shun
AU  - Juan YS
AD  - Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung Medical 
      University, Kaohsiung, Taiwan.
FAU - Tsai, Eing-Mei
AU  - Tsai EM
AD  - Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, 
      Kaohsiung Medical University, Kaohsiung, Taiwan.
AD  - Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical 
      University, Kaohsiung, Taiwan.
FAU - Lin, Kun-Ling
AU  - Lin KL
AUID- ORCID: 0000-0003-0856-6423
AD  - Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, 
      Kaohsiung Medical University, Kaohsiung, Taiwan. nancylin95@gmail.com.
AD  - Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical 
      University, Kaohsiung, Taiwan. nancylin95@gmail.com.
LA  - eng
PT  - Journal Article
DEP - 20180320
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cohort Studies
MH  - Female
MH  - Humans
MH  - Laparoscopy/*methods
MH  - Middle Aged
MH  - Pelvic Organ Prolapse/*surgery
MH  - Postoperative Period
MH  - Quality of Life
MH  - Sexual Behavior
MH  - Surgical Mesh
MH  - Surveys and Questionnaires
MH  - Treatment Outcome
MH  - Urinary Bladder, Overactive
MH  - Urodynamics
MH  - Uterine Prolapse/*surgery
MH  - Uterus/surgery
MH  - Vagina/surgery
PMC - PMC5861080
COIS- The authors declare no competing interests.
EDAT- 2018/03/22 06:00
MHDA- 2019/11/05 06:00
PMCR- 2018/03/20
CRDT- 2018/03/22 06:00
PHST- 2017/11/14 00:00 [received]
PHST- 2018/02/19 00:00 [accepted]
PHST- 2018/03/22 06:00 [entrez]
PHST- 2018/03/22 06:00 [pubmed]
PHST- 2019/11/05 06:00 [medline]
PHST- 2018/03/20 00:00 [pmc-release]
AID - 10.1038/s41598-018-23285-7 [pii]
AID - 23285 [pii]
AID - 10.1038/s41598-018-23285-7 [doi]
PST - epublish
SO  - Sci Rep. 2018 Mar 20;8(1):4872. doi: 10.1038/s41598-018-23285-7.