PMID- 29561461
OWN - NLM
STAT- MEDLINE
DCOM- 20180503
LR  - 20221207
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 97
IP  - 12
DP  - 2018 Mar
TI  - A randomized controlled study to evaluate the effect of pharmacist-led 
      educational intervention on glycemic control, self-care activities and disease 
      knowledge among type 2 diabetes patients: A consort compliant study protocol.
PG  - e9847
LID - 10.1097/MD.0000000000009847 [doi]
LID - e9847
AB  - BACKGROUND: Diabetes self-care activities, like, healthy diet, regular exercise, 
      self-monitoring of blood glucose, and rational use of medicines are considered to 
      play a vital role in establishing euglycemia. Health literacy among type 2 
      diabetes mellitus (T2DM) patients in Pakistan is very low, which is the most 
      likely cause for poor clinical outcomes. This study is designed to investigate 
      the impact of pharmacist-led educational intervention on glycemic control, 
      self-care activities and disease knowledge among T2DM patients in Pakistan. 
      METHODS: In this randomized controlled trail, effectiveness of a 6-month 
      pharmacist-led educational intervention will be examined on glycemic control, 
      diabetes self-care activities and disease knowledge of 80 adult T2DM patients 
      (age >30 years) with poorly controlled T2DM (HbA1c> 7%), after randomizing them 
      into intervention and control groups, at diabetes care clinic of Capital Hospital 
      Islamabad, Pakistan. RESULTS: The primary outcome is change in patients' HbA1c, 
      whereas, changes in self-care activities and patients' disease knowledge are the 
      secondary outcomes. After baseline assessment of their self-care activities and 
      disease knowledge by using validated Urdu versions of Diabetes Self-management 
      Questionnaire (DSMQ) and Diabetes Knowledge Questionnaire (DKQ), respectively, 
      interventional group patients will be supplemented with a face-to-face 
      pharmacist-led educational intervention, whereas, the control group will receive 
      usual care. Intervention arm patients will be educated successively at their 
      first follow-up visit (12th week) and telephonically after every 4 weeks. All 
      assessments will be made at baseline and end of trail for both intervention and 
      control groups. Multivariate general linear model will be applied to analyze the 
      effects of the intervention. CONCLUSION: Glycemic control in T2DM patients 
      requires optimum self-care activities. This study is an attempt to improve 
      self-care behaviors among poorly controlled T2DM patients who are at higher risk 
      of diabetes-associated late complications.
FAU - Bukhsh, Allah
AU  - Bukhsh A
AD  - School of Pharmacy, Monash University, Jalan Lagoon, Selatan, Selangor, Malaysia.
AD  - Institute of Pharmaceutical Sciences, University of Veterinary and Animal 
      Sciences, Lahore.
FAU - Nawaz, Muhammad Sarfraz
AU  - Nawaz MS
AD  - Department of Pharmacy, Quaid-i-Azam University.
FAU - Ahmed, Hafiz Sajjad
AU  - Ahmed HS
AD  - Capital Hospital Islamabad, Pakistan.
FAU - Khan, Tahir Mehmood
AU  - Khan TM
AD  - School of Pharmacy, Monash University, Jalan Lagoon, Selatan, Selangor, Malaysia.
AD  - Institute of Pharmaceutical Sciences, University of Veterinary and Animal 
      Sciences, Lahore.
AD  - Asian Centre for Evidence Synthesis in Population, Implementation and Clinical 
      Outcomes (PICO), Health and Well-being Cluster, Monash University Malaysia, 
      Bandar Sunway, Selangor, Malaysia.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Glycated Hemoglobin A)
SB  - IM
MH  - Diabetes Mellitus, Type 2/blood/psychology/*therapy
MH  - Glycated Hemoglobin/*metabolism
MH  - *Health Knowledge, Attitudes, Practice
MH  - Humans
MH  - *Patient Education as Topic
MH  - Patient Selection
MH  - *Pharmacists
MH  - *Self Care/methods
MH  - Time Factors
PMC - PMC5895327
COIS- The authors report no conflicts of interest.
EDAT- 2018/03/22 06:00
MHDA- 2018/05/04 06:00
PMCR- 2018/03/23
CRDT- 2018/03/22 06:00
PHST- 2018/03/22 06:00 [entrez]
PHST- 2018/03/22 06:00 [pubmed]
PHST- 2018/05/04 06:00 [medline]
PHST- 2018/03/23 00:00 [pmc-release]
AID - 00005792-201803230-00056 [pii]
AID - MD-D-17-06092 [pii]
AID - 10.1097/MD.0000000000009847 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2018 Mar;97(12):e9847. doi: 10.1097/MD.0000000000009847.