PMID- 29564551
OWN - NLM
STAT- MEDLINE
DCOM- 20180514
LR  - 20181114
IS  - 1435-702X (Electronic)
IS  - 0721-832X (Linking)
VI  - 256
IP  - 5
DP  - 2018 May
TI  - Preexisting epiretinal membrane is associated with pseudophakic cystoid macular 
      edema.
PG  - 909-917
LID - 10.1007/s00417-018-3954-4 [doi]
AB  - PURPOSE: The purpose of the present study was to evaluate whether preexisting 
      epiretinal membrane (ERM) is a significant risk factor for developing 
      pseudophakic cystoid macular edema (PCME). METHODS: Two hundred four consecutive 
      eyes and 153 consecutive eyes without preexisting epiretinal membranes were 
      retrospectively compared regarding PCME development following phacoemulsification 
      with posterior chamber lens implantation. Patients with vascular retinal 
      diseases, uveitis, trauma, neovascular macular degeneration, chronic inflammatory 
      conditions, diabetic retinopathy, endophthalmitis, eventful cataract surgery, and 
      combination of cataract surgery and vitrectomy during the observation period were 
      excluded. Macular examination was performed using spectral-domain optical 
      coherence tomography (SD-OCT) before as well as at 4, 8, 12, 16, 24, and 36 weeks 
      after cataract surgery. Univariate and multivariate logistic regression analyses 
      were calculated. RESULTS: PCME occurred in 32 of 204 eyes with preexisting ERM 
      (15.7%), whereas 9 of 153 eyes without preexisting ERM (5.9%) developed PCME. The 
      risk of PCME was significantly increased in eyes with ERM (p = 0.007). By 
      multivariate logistic regression analysis, factors predictive of PCME included 
      the history of previous pars plana vitrectomy for retinal detachment (odds ratio 
      (OR) 3.619 [95% confidence interval (CI) 1.242 to 10.258]; p = 0.016) as well as 
      the preexistence of ERM (OR 3.885 [95% CI 1.162 to 17.762]; p = 0.04). 
      CONCLUSION: Preexisting ERM seems to be associated with an increased risk of PCME 
      following cataract surgery. Therefore, this risk should be considered in surgery 
      planning, preoperative medication, and follow-up care after surgery.
FAU - Schaub, Friederike
AU  - Schaub F
AD  - Department of Ophthalmology, University of Cologne, Kerpener Strasse 62, 50924, 
      Cologne, Germany. friederike.schaub@uk-koeln.de.
FAU - Adler, Werner
AU  - Adler W
AD  - Department of Medical Informatics, Biometry and Epidemiology, Friedrich-Alexander 
      University Erlangen-Nurnberg, Erlangen, Germany.
FAU - Enders, Philip
AU  - Enders P
AD  - Department of Ophthalmology, University of Cologne, Kerpener Strasse 62, 50924, 
      Cologne, Germany.
FAU - Koenig, Meike C
AU  - Koenig MC
AD  - Department of Ophthalmology, University of Cologne, Kerpener Strasse 62, 50924, 
      Cologne, Germany.
FAU - Koch, Konrad R
AU  - Koch KR
AD  - Department of Ophthalmology, University of Cologne, Kerpener Strasse 62, 50924, 
      Cologne, Germany.
FAU - Cursiefen, Claus
AU  - Cursiefen C
AD  - Department of Ophthalmology, University of Cologne, Kerpener Strasse 62, 50924, 
      Cologne, Germany.
FAU - Kirchhof, Bernd
AU  - Kirchhof B
AD  - Department of Ophthalmology, University of Cologne, Kerpener Strasse 62, 50924, 
      Cologne, Germany.
FAU - Heindl, Ludwig M
AU  - Heindl LM
AD  - Department of Ophthalmology, University of Cologne, Kerpener Strasse 62, 50924, 
      Cologne, Germany.
LA  - eng
GR  - FOR 2240/Deutsche Forschungsgemeinschaft/
GR  - FOR 2240/Deutsche Forschungsgemeinschaft/
PT  - Journal Article
DEP - 20180321
PL  - Germany
TA  - Graefes Arch Clin Exp Ophthalmol
JT  - Graefe's archive for clinical and experimental ophthalmology = Albrecht von 
      Graefes Archiv fur klinische und experimentelle Ophthalmologie
JID - 8205248
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Epiretinal Membrane/*complications/diagnosis
MH  - Female
MH  - Humans
MH  - Lens Implantation, Intraocular
MH  - Macular Edema/diagnosis/*etiology
MH  - Male
MH  - Middle Aged
MH  - Phacoemulsification
MH  - Pseudophakia/diagnosis/*etiology
MH  - Retinal Detachment/surgery
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Tomography, Optical Coherence
MH  - Visual Acuity
MH  - Vitrectomy
OTO - NOTNLM
OT  - Cataract
OT  - Complication
OT  - Cystoid macular edema
OT  - Epiretinal membrane
OT  - Phacoemulsification
EDAT- 2018/03/23 06:00
MHDA- 2018/05/15 06:00
CRDT- 2018/03/23 06:00
PHST- 2017/06/22 00:00 [received]
PHST- 2018/03/02 00:00 [accepted]
PHST- 2018/02/14 00:00 [revised]
PHST- 2018/03/23 06:00 [pubmed]
PHST- 2018/05/15 06:00 [medline]
PHST- 2018/03/23 06:00 [entrez]
AID - 10.1007/s00417-018-3954-4 [pii]
AID - 10.1007/s00417-018-3954-4 [doi]
PST - ppublish
SO  - Graefes Arch Clin Exp Ophthalmol. 2018 May;256(5):909-917. doi: 
      10.1007/s00417-018-3954-4. Epub 2018 Mar 21.