PMID- 29566142
OWN - NLM
STAT- MEDLINE
DCOM- 20190528
LR  - 20240109
IS  - 1873-734X (Electronic)
IS  - 1010-7940 (Linking)
VI  - 54
IP  - 3
DP  - 2018 Sep 1
TI  - Outcomes of the anatomical repair in patients with congenitally corrected 
      transposition of the great arteries: lessons learned in a high-volume centre.
PG  - 532-538
LID - 10.1093/ejcts/ezy116 [doi]
AB  - OBJECTIVES: The physiological repair of the congenitally corrected transposition 
      of the great arteries (ccTGA) has been associated with a long-term risk of the 
      right ventricular dysfunction and tricuspid valve regurgitation. On the other 
      side, the anatomical repair with the restoration of the left ventricle in a 
      systemic position has been hypothesized to improve long-term outcomes. The aim of 
      this study was to determine the results of the anatomical repair. METHODS: 
      Between 1990 and 2015, 39 patients underwent an anatomical repair of a ccTGA. The 
      median age was 7 years (range from 8 days to 42.8 years). Eighteen (46%) patients 
      had a double switch. Of these, 21 (54%) patients had an atrial switch with a 
      Rastelli technique (n = 16, 41%), with a reparation a l'etage ventriculaire (REV) 
      procedure (n = 4, 10%) or a truncal rotation (n = 1, 3%). The follow-up was 100% 
      complete at 2 years with a median follow-up of 3.17 years (range 0-26 years). 
      RESULTS: The early mortality was 10% (n = 4) and the late mortality was 20% 
      (n = 8). The long-term survival was 77 +/- 10% at 10 years for the double switch 
      group and 62 +/- 11% at 10 years for the Rastelli group (P = 0.25). Eight (20%) 
      patients required reintervention. Freedom from reoperation at 10 years was 
      82 +/- 11% in the double switch group and 88 +/- 11% in the Rastelli group. At the 
      last follow-up, 23 (82%) patients were in New York Heart Association (NYHA) 
      functional class I and 2 (7%) patients in NYHA class II. CONCLUSIONS: The 
      anatomical repair of the ccTGA is associated with significant early mortality and 
      morbidity. However, the long-term functional status is satisfactory. The 
      anatomical repair of the ccTGA should be reserved for a carefully selected group 
      of patients.
FAU - Lenoir, Marien
AU  - Lenoir M
AD  - Division of Pediatric Cardiac Surgery, University Paris Descartes and Necker Sick 
      Children Hospital, Paris, France.
FAU - Bouhout, Ismail
AU  - Bouhout I
AD  - Division of Cardiac Surgery, Montreal Heart Institute, University of Montreal 
      School of Medicine, Montreal, QC, Canada.
FAU - Gaudin, Regis
AU  - Gaudin R
AD  - Division of Pediatric Cardiac Surgery, University Paris Descartes and Necker Sick 
      Children Hospital, Paris, France.
FAU - Raisky, Olivier
AU  - Raisky O
AD  - Division of Pediatric Cardiac Surgery, University Paris Descartes and Necker Sick 
      Children Hospital, Paris, France.
FAU - Vouhe, Pascal
AU  - Vouhe P
AD  - Division of Pediatric Cardiac Surgery, University Paris Descartes and Necker Sick 
      Children Hospital, Paris, France.
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Eur J Cardiothorac Surg
JT  - European journal of cardio-thoracic surgery : official journal of the European 
      Association for Cardio-thoracic Surgery
JID - 8804069
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - *Cardiac Surgical Procedures/adverse effects/methods/mortality/statistics & 
      numerical data
MH  - Child
MH  - Child, Preschool
MH  - Congenitally Corrected Transposition of the Great Arteries
MH  - Female
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Male
MH  - Retrospective Studies
MH  - Transposition of Great Vessels/epidemiology/mortality/*surgery
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2018/03/23 06:00
MHDA- 2019/05/29 06:00
CRDT- 2018/03/23 06:00
PHST- 2017/09/18 00:00 [received]
PHST- 2018/02/21 00:00 [accepted]
PHST- 2018/03/23 06:00 [pubmed]
PHST- 2019/05/29 06:00 [medline]
PHST- 2018/03/23 06:00 [entrez]
AID - 4939310 [pii]
AID - 10.1093/ejcts/ezy116 [doi]
PST - ppublish
SO  - Eur J Cardiothorac Surg. 2018 Sep 1;54(3):532-538. doi: 10.1093/ejcts/ezy116.