PMID- 29566549
OWN - NLM
STAT- MEDLINE
DCOM- 20181113
LR  - 20181113
IS  - 1600-0455 (Electronic)
IS  - 0284-1851 (Linking)
VI  - 59
IP  - 12
DP  - 2018 Dec
TI  - Mid-term development of the right ventricle in competitive athletes.
PG  - 1422-1430
LID - 10.1177/0284185118764203 [doi]
AB  - BACKGROUND: Long-term intensive training induces physiological, morphological, 
      and functional adaption of the athlete's heart. PURPOSE: To evaluate the 
      development of athlete's heart during a mid-term follow-up of competitive 
      athletes using cardiac magnetic resonance (CMR). MATERIAL AND METHODS: Eighteen 
      competitive long-distance runners and triathletes (age 43 +/- 13 years, 3 women) 
      were prospectively examined in a longitudinal follow-up study 5.05 +/- 0.6 years 
      after baseline. CMR at 1.5-T was performed for functional and late gadolinium 
      enhancement (LGE) imaging. Left ventricular (LV) and right ventricular (RV) 
      end-diastolic volume (LVEDV, RVEDV) as well as ejection fraction (LVEF, RVEF), LV 
      myocardial mass (LVMM), and atrial sizes were determined and compared to baseline 
      in matched pairs statistics for paired difference. RESULTS: LVEDV (197 +/- 38 mL 
      vs. 196 +/- 38 mL, paired difference -0.9 mL, P = 0.7) and LVEF (62 +/- 7% vs. 
      62 +/- 5%, paired difference 0.1%, P = 0.9) did not change during the follow-up 
      period, whereas LVMM increased significantly (149 +/- 31 g vs.164 +/- 32 g, paired 
      difference 14 g, P < 0.0001). RVEDV significantly increased from 221 +/- 47 mL at 
      baseline to 230 +/- 52 mL (paired difference 10 mL, P = 0.0033). RVEF decreased 
      from baseline 57 +/- 8% to 53 +/- 7% (paired difference -3%, P = 0.0234). Left atrial 
      size showed no significant changes (24 +/- 5 cm(2) vs. 25 +/- 6 cm(2), paired 
      difference 0.5 cm(2), P = 0.17) and right atrial size increased significantly 
      (30 +/- 5 cm(2) vs. 32 +/- 4 cm(2), paired difference 2 cm(2), P = 0.0054). 
      CONCLUSION: This study supports the theory of ongoing remodeling in an athlete's 
      heart. Predominantly the right heart can further enlarge in a mid-term period. 
      This response seems not linearly dependent on a steady, decreased, or increased 
      training volume.
FAU - Krumm, Patrick
AU  - Krumm P
AUID- ORCID: 0000-0003-1705-8439
AD  - 1 Department of Diagnostic and Interventional Radiology, Eberhard Karls 
      University of Tubingen, Tubingen, Germany.
FAU - Krauss, Stefan
AU  - Krauss S
AD  - 2 Department of Internal Medicine V, Sports Medicine, Eberhard Karls University 
      of Tubingen, Tubingen, Germany.
FAU - Mangold, Stefanie
AU  - Mangold S
AD  - 1 Department of Diagnostic and Interventional Radiology, Eberhard Karls 
      University of Tubingen, Tubingen, Germany.
FAU - Zitzelsberger, Tanja
AU  - Zitzelsberger T
AD  - 1 Department of Diagnostic and Interventional Radiology, Eberhard Karls 
      University of Tubingen, Tubingen, Germany.
FAU - Klumpp, Bernhard D
AU  - Klumpp BD
AD  - 1 Department of Diagnostic and Interventional Radiology, Eberhard Karls 
      University of Tubingen, Tubingen, Germany.
AD  - 3 Department of Radiology, Rems-Murr-Clinic, Winnenden, Germany.
FAU - Nikolaou, Konstantin
AU  - Nikolaou K
AD  - 1 Department of Diagnostic and Interventional Radiology, Eberhard Karls 
      University of Tubingen, Tubingen, Germany.
FAU - Niess, Andreas M
AU  - Niess AM
AD  - 2 Department of Internal Medicine V, Sports Medicine, Eberhard Karls University 
      of Tubingen, Tubingen, Germany.
FAU - Kramer, Ulrich
AU  - Kramer U
AD  - 1 Department of Diagnostic and Interventional Radiology, Eberhard Karls 
      University of Tubingen, Tubingen, Germany.
AD  - 3 Department of Radiology, Rems-Murr-Clinic, Winnenden, Germany.
FAU - Burgstahler, Christof
AU  - Burgstahler C
AD  - 2 Department of Internal Medicine V, Sports Medicine, Eberhard Karls University 
      of Tubingen, Tubingen, Germany.
LA  - eng
PT  - Journal Article
DEP - 20180322
PL  - England
TA  - Acta Radiol
JT  - Acta radiologica (Stockholm, Sweden : 1987)
JID - 8706123
RN  - 0 (Contrast Media)
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Adult
MH  - Aged
MH  - *Athletes
MH  - Contrast Media
MH  - Female
MH  - Follow-Up Studies
MH  - Gadolinium
MH  - Heart Ventricles/*diagnostic imaging
MH  - Humans
MH  - Image Enhancement/methods
MH  - Longitudinal Studies
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Ventricular Function/*physiology
MH  - Young Adult
OTO - NOTNLM
OT  - Athletes
OT  - atria
OT  - function
OT  - heart
OT  - ventricles
OT  - volume
EDAT- 2018/03/24 06:00
MHDA- 2018/11/14 06:00
CRDT- 2018/03/24 06:00
PHST- 2018/03/24 06:00 [pubmed]
PHST- 2018/11/14 06:00 [medline]
PHST- 2018/03/24 06:00 [entrez]
AID - 10.1177/0284185118764203 [doi]
PST - ppublish
SO  - Acta Radiol. 2018 Dec;59(12):1422-1430. doi: 10.1177/0284185118764203. Epub 2018 
      Mar 22.