PMID- 29566588 OWN - NLM STAT- MEDLINE DCOM- 20200603 LR - 20200603 IS - 1464-0694 (Electronic) IS - 0960-2011 (Linking) VI - 30 IP - 1 DP - 2020 Jan TI - Effectiveness of ReSET; a strategic executive treatment for executive dysfunctioning in patients with Parkinson's disease. PG - 67-84 LID - 10.1080/09602011.2018.1452761 [doi] AB - In this multicentre randomised controlled trial (RCT), 43 patients with Parkinson's disease (PD) were randomly allocated to either the experimental condition receiving cognitive rehabilitation including strategy training (ReSET; Strategic Executive Treatment, n = 24) or to the control condition receiving computerised repetitive practice training for attention (Cogniplus, n = 16). We expected that strategy training (ReSET) would be more effective than cognitive training (Cogniplus) in improving patients' everyday life executive functioning. Neuropsychological assessment was administered at baseline, at 2 weeks and 3-5 months post-treatment. Primary outcome measure was the Role Resumption List (RRL). Secondary outcome measures were treatment goal attainment (TGA), Dysexecutive Questionnaire (DEX), Parkinson's Disease Questionnaire (PDQ-39), Zarit Burden Interview (ZBI) and neuropsychological tests. No effects of treatment were found on the primary outcome measure and on neuropsychological tests, except for one test of attention. At 2 weeks and 3-5 months post-treatment, PD patients in both the ReSET and Cogniplus group reported a significant improvement in everyday life executive functioning, as measured with TGA and the DEX-self, with an advantage for ReSET only shortly after treatment. Given these results and that PD patients were able to adhere to these treatments despite their motor symptoms and fatigue (i.e., the drop-out rate was small), we conclude that both strategy training and cognitive training for impairments in EF might be beneficial and feasible for PD patients. FAU - Vlagsma, Thialda T AU - Vlagsma TT AD - Department of Clinical & Developmental Neuropsychology, University of Groningen, Groningen, The Netherlands. FAU - Duits, Annelien A AU - Duits AA AD - Department of Psychiatry and Psychology, Maastricht University Medical Center, Maastricht, The Netherlands. FAU - Dijkstra, Hilde T AU - Dijkstra HT AD - Department of Medical psychology, Medical Center Nij Smellinghe, Drachten, The Netherlands. FAU - van Laar, Teus AU - van Laar T AD - Department of Neurology, University Medical Center Groningen, Groningen, The Netherlands. FAU - Spikman, Jacoba M AU - Spikman JM AD - Department of Clinical & Developmental Neuropsychology, University of Groningen, Groningen, The Netherlands. AD - Department of Neurology, University Medical Center Groningen, Groningen, The Netherlands. LA - eng PT - Journal Article PT - Multicenter Study PT - Randomized Controlled Trial DEP - 20180322 PL - England TA - Neuropsychol Rehabil JT - Neuropsychological rehabilitation JID - 9112672 SB - IM MH - Adult MH - Aged MH - Attention MH - Cognition Disorders/*etiology/*rehabilitation MH - *Executive Function MH - Feasibility Studies MH - Female MH - Humans MH - Male MH - Middle Aged MH - *Neurological Rehabilitation MH - Neuropsychological Tests MH - Parkinson Disease/*psychology/*rehabilitation MH - Therapy, Computer-Assisted MH - Treatment Outcome OTO - NOTNLM OT - Executive impairments OT - Neuropsychological rehabilitation OT - Parkinson's disease OT - Strategy training EDAT- 2018/03/24 06:00 MHDA- 2020/06/04 06:00 CRDT- 2018/03/24 06:00 PHST- 2018/03/24 06:00 [pubmed] PHST- 2020/06/04 06:00 [medline] PHST- 2018/03/24 06:00 [entrez] AID - 10.1080/09602011.2018.1452761 [doi] PST - ppublish SO - Neuropsychol Rehabil. 2020 Jan;30(1):67-84. doi: 10.1080/09602011.2018.1452761. Epub 2018 Mar 22.