PMID- 29569243
OWN - NLM
STAT- MEDLINE
DCOM- 20190722
LR  - 20190722
IS  - 1558-9307 (Electronic)
IS  - 0024-4201 (Linking)
VI  - 53
IP  - 2
DP  - 2018 Feb
TI  - Dietary High-Oleic Acid Soybean Oil Dose Dependently Attenuates Egg Yolk Content 
      of n-3 Polyunsaturated Fatty Acids in Laying Hens Fed Supplemental Flaxseed Oil.
PG  - 235-249
LID - 10.1002/lipd.12016 [doi]
AB  - Chickens can hepatically synthesize eicosapentaenoic acid (20:5 n-3) and 
      docosahexaenoic acid (22:6 n-3) from alpha-linolenic acid (ALA; 18:3 n-3); however, 
      the process is inefficient and competitively inhibited by dietary linoleic acid 
      (LNA; 18:2 n-6). In the present study, the influence of dietary high-oleic acid 
      (OLA; 18:1 n-9) soybean oil (HOSO) on egg and tissue deposition of ALA and n-3 
      polyunsaturated fatty acids (PUFA) synthesized from dietary ALA was investigated 
      in laying hens fed a reduced-LNA base diet supplemented with high-ALA flaxseed 
      oil (FLAX). We hypothesized that reducing the dietary level of LNA would promote 
      greater hepatic conversion of ALA to very long-chain (VLC; >20C) n-3 PUFA, while 
      supplemental dietary HOSO would simultaneously further enrich eggs with OLA 
      without influencing egg n-3 PUFA contents. Nine 51-week-old hens each were fed 0, 
      10, 20, or 40 g HOSO/kg diet for 12 weeks. Within each group, supplemental 
      dietary FLAX was increased every 3 weeks from 0 to 10 to 20 to 40 g/kg diet. 
      Compared to controls, dietary FLAX maximally enriched the total n-3 and VLC n-3 
      PUFA contents in egg yolk by 9.4-fold and 2.2-fold, respectively, while feeding 
      hens 40 g HOSO/kg diet maximally attenuated the yolk deposition of ALA, VLC n-3 
      PUFA, and total n-3 PUFA by 37, 15, and 32%, respectively. These results suggest 
      that dietary OLA is not neutral with regard to the overall process by which 
      dietary ALA is absorbed, metabolized, and deposited into egg yolk, either intact 
      or in the form of longer-chain/more unsaturated n-3 PUFA derivatives.
CI  - (c) 2018 AOCS.
FAU - Elkin, Robert G
AU  - Elkin RG
AD  - Department of Animal Science, The Pennsylvania State University, University Park, 
      PA, 16802, USA.
FAU - Kukorowski, Alexandra N
AU  - Kukorowski AN
AD  - Department of Animal Science, The Pennsylvania State University, University Park, 
      PA, 16802, USA.
FAU - Ying, Yun
AU  - Ying Y
AD  - Department of Animal Science, The Pennsylvania State University, University Park, 
      PA, 16802, USA.
FAU - Harvatine, Kevin J
AU  - Harvatine KJ
AD  - Department of Animal Science, The Pennsylvania State University, University Park, 
      PA, 16802, USA.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180322
PL  - United States
TA  - Lipids
JT  - Lipids
JID - 0060450
RN  - 0 (Fatty Acids, Omega-3)
RN  - 2UMI9U37CP (Oleic Acid)
RN  - 8001-22-7 (Soybean Oil)
RN  - 8001-26-1 (Linseed Oil)
SB  - IM
MH  - *Animal Feed
MH  - Animals
MH  - Chickens
MH  - Dietary Supplements
MH  - Egg Yolk/*chemistry/*drug effects
MH  - Fatty Acids, Omega-3/*analysis
MH  - Linseed Oil/*administration & dosage/chemistry
MH  - Oleic Acid/administration & dosage/*pharmacology
MH  - Soybean Oil/administration & dosage/*pharmacology
OTO - NOTNLM
OT  - Egg yolk
OT  - Laying hen
OT  - Oleic acid
OT  - n-3 Polyunsaturated fatty acids
OT  - alpha-Linolenic acid
EDAT- 2018/03/24 06:00
MHDA- 2019/07/23 06:00
CRDT- 2018/03/24 06:00
PHST- 2017/08/23 00:00 [received]
PHST- 2017/12/01 00:00 [revised]
PHST- 2017/12/08 00:00 [accepted]
PHST- 2018/03/24 06:00 [pubmed]
PHST- 2019/07/23 06:00 [medline]
PHST- 2018/03/24 06:00 [entrez]
AID - 10.1002/lipd.12016 [doi]
PST - ppublish
SO  - Lipids. 2018 Feb;53(2):235-249. doi: 10.1002/lipd.12016. Epub 2018 Mar 22.