PMID- 29570819 OWN - NLM STAT- MEDLINE DCOM- 20190618 LR - 20190618 IS - 1440-1681 (Electronic) IS - 0305-1870 (Linking) VI - 45 IP - 8 DP - 2018 Aug TI - Hyperuricaemia and type 2 diabetes mellitus. PG - 870 LID - 10.1111/1440-1681.12937 [doi] AB - Choi et al reported the effect of hyperuricaemia on the new-onset type 2 diabetes mellitus (T2DM). I present three queries. (i) Insulin is considered to stimulate uric acid reabsorption via specific transporter and the effect of hyperuricaemia on the new-onset T2DM should be evaluated by considering insulin resistance. (ii) There is a limitation in the number of events for stable estimates. (iii) Obesity and sex should be considered for the analysis. CI - (c) 2018 John Wiley & Sons Australia, Ltd. FAU - Kawada, Tomoyuki AU - Kawada T AUID- ORCID: 0000-0002-4426-4644 AD - Department of Hygiene and Public Health, Nippon Medical School, Tokyo, Japan. LA - eng PT - Comment PT - Letter PL - Australia TA - Clin Exp Pharmacol Physiol JT - Clinical and experimental pharmacology & physiology JID - 0425076 RN - 0 (Insulin) RN - 268B43MJ25 (Uric Acid) SB - IM CON - Clin Exp Pharmacol Physiol. 2018 Jun;45(6):499-506. PMID: 29266345 MH - *Diabetes Mellitus, Type 2 MH - Humans MH - *Hyperuricemia MH - Insulin MH - *Insulin Resistance MH - Uric Acid OTO - NOTNLM OT - hyperuricaemia OT - prospective study OT - type 2 diabetes mellitus EDAT- 2018/03/24 06:00 MHDA- 2019/06/19 06:00 CRDT- 2018/03/24 06:00 PHST- 2018/02/20 00:00 [received] PHST- 2018/03/13 00:00 [accepted] PHST- 2018/03/24 06:00 [pubmed] PHST- 2019/06/19 06:00 [medline] PHST- 2018/03/24 06:00 [entrez] AID - 10.1111/1440-1681.12937 [doi] PST - ppublish SO - Clin Exp Pharmacol Physiol. 2018 Aug;45(8):870. doi: 10.1111/1440-1681.12937.