PMID- 29571635
OWN - NLM
STAT- MEDLINE
DCOM- 20181126
LR  - 20220410
IS  - 1878-7533 (Electronic)
IS  - 1550-7289 (Linking)
VI  - 14
IP  - 6
DP  - 2018 Jun
TI  - Lack of correlation between gastroesophageal reflux disease symptoms and 
      esophageal lesions after sleeve gastrectomy.
PG  - 751-756
LID - S1550-7289(18)30087-X [pii]
LID - 10.1016/j.soard.2018.02.008 [doi]
AB  - BACKGROUND: The postoperative development or worsening of gastroesophageal reflux 
      disease (GERD) represents the major drawback of laparoscopic sleeve gastrectomy 
      (SG). A GERD diagnosis is often based only on symptoms and proton pump inhibitors 
      (PPI) intake, while objective tests like esophagogastroduodenoscopy and pH 
      measurements are performed less frequently. OBJECTIVES: To evaluate the 
      association between reflux symptoms and GERD-related esophageal lesions. 
      SETTINGS: University hospital, Rome, Italy. METHODS: A comprehensive clinical 
      control entailing GERD symptoms, PPI intake, and esophagogastroduodenoscopy was 
      proposed to all patients who underwent SG between June 2007 and February 2011, 
      irrespective of the presence of GERD symptoms. One hundred forty-four of 219 
      patients agreed to take part in the study (follow-up rate: 65.8%). RESULTS: After 
      a mean follow-up of 66 months, GERD symptoms and PPI intake were recorded in 
      70.2% and 63.9% of patients, respectively. Mean visual analogue scale score was 
      2.9 +/- 3.3. The overall frequency of erosive esophagitis was 59.8%, while 
      nondysplastic Barrett's esophagus was detected in 13.1%. The frequency of 
      esophageal biliary reflux was 68%. GERD symptoms and visual analogue scale score 
      were not significantly associated with the development of erosive esophagitis and 
      Barrett's esophagus and the severity of the esophageal lesions. Moreover, the 
      frequency of erosive esophagitis and Barrett's esophagus in patients consuming 
      PPI were similar to that of patients without PPI. CONCLUSION: Symptoms 
      investigation alone is not a reliable tool to diagnose GERD after SG. The use of 
      objective diagnostic tests, such as esophagogastroduodenoscopy, should be 
      carefully considered in the postoperative follow-up schedule of SG patients.
CI  - Copyright (c) 2018 American Society for Bariatric Surgery. Published by Elsevier 
      Inc. All rights reserved.
FAU - Soricelli, Emanuele
AU  - Soricelli E
AD  - Department of Surgical Sciences, Policlinico Umberto I, Sapienza University of 
      Rome, Rome, Italy. Electronic address: emanuele.soricelli@gmail.com.
FAU - Casella, Giovanni
AU  - Casella G
AD  - Department of Surgical Sciences, Policlinico Umberto I, Sapienza University of 
      Rome, Rome, Italy.
FAU - Baglio, Giovanni
AU  - Baglio G
AD  - Sapienza University of Rome, Rome, Italy.
FAU - Maselli, Roberta
AU  - Maselli R
AD  - Endoscopic unit, Division of Gastroenterology, Humanitas Research Hospital, 
      Rozzano, Milan, Italy.
FAU - Ernesti, Ilaria
AU  - Ernesti I
AD  - Department of Experimental Medicine-Medical Physiopathology, Food Science and 
      Endocrinology Section, Sapienza University of Rome, Rome, Italy.
FAU - Genco, Alfredo
AU  - Genco A
AD  - Department of Surgical Sciences, Policlinico Umberto I, Sapienza University of 
      Rome, Rome, Italy.
LA  - eng
PT  - Journal Article
DEP - 20180213
PL  - United States
TA  - Surg Obes Relat Dis
JT  - Surgery for obesity and related diseases : official journal of the American 
      Society for Bariatric Surgery
JID - 101233161
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Bariatric Surgery/*adverse effects
MH  - Barrett Esophagus/*etiology
MH  - Case-Control Studies
MH  - Endoscopy, Digestive System/methods
MH  - Esophagitis, Peptic/*etiology
MH  - Gastrectomy/*adverse effects
MH  - Gastroesophageal Reflux/drug therapy/*etiology
MH  - Humans
MH  - Laparoscopy/*adverse effects
MH  - Postoperative Complications/etiology
MH  - Prospective Studies
MH  - Proton Pump Inhibitors/therapeutic use
OTO - NOTNLM
OT  - Barrett's esophagus
OT  - Esophageal biliary reflux
OT  - Gastroesophageal reflux disease
OT  - Sleeve gastrectomy
EDAT- 2018/03/25 06:00
MHDA- 2018/11/27 06:00
CRDT- 2018/03/25 06:00
PHST- 2017/11/03 00:00 [received]
PHST- 2018/01/12 00:00 [revised]
PHST- 2018/02/04 00:00 [accepted]
PHST- 2018/03/25 06:00 [pubmed]
PHST- 2018/11/27 06:00 [medline]
PHST- 2018/03/25 06:00 [entrez]
AID - S1550-7289(18)30087-X [pii]
AID - 10.1016/j.soard.2018.02.008 [doi]
PST - ppublish
SO  - Surg Obes Relat Dis. 2018 Jun;14(6):751-756. doi: 10.1016/j.soard.2018.02.008. 
      Epub 2018 Feb 13.