PMID- 29575943 OWN - NLM STAT- MEDLINE DCOM- 20190930 LR - 20191101 IS - 1360-0451 (Electronic) IS - 0954-0121 (Print) IS - 0954-0121 (Linking) VI - 30 IP - 11 DP - 2018 Nov TI - Prevalence of prenatal and postpartum depression and associated factors among HIV-infected women in public primary care in rural South Africa: a longitudinal study. PG - 1372-1379 LID - 10.1080/09540121.2018.1455960 [doi] AB - This study aimed to assess the longitudinal prevalence of prenatal and postnatal depression and associated factors among HIV-infected women in rural South Africa. In a longitudinal, cluster-randomized, prevention of mother to child transmission (PMTCT) intervention trial, 681 HIV-infected prenatal women in 12 community health centres in Mpumalanga province, South Africa, were recruited in 2015 by consecutive sampling at 8-24 weeks pregnancy and followed up at 32 weeks prenatally, and 6 and 12 months postpartum (retention rate = 59.2%). Results indicate that at baseline, 48.7% of the women screened positive for depression (scores of >/=13 on the "Edinburgh Postnatal Depression Scale 10"), while postnatally (at 12 months) the prevalence was 35.6%. Mothers who did not have depression before or after were 205 (50.1%), those who had depression before and after were 58 (14.4%), those who had depression only before were 81 (20.1%), and those who had depression only after were 59 (14.6%). In multinominal logistic regression analyses, less education and physical and psychological intimate partner violence were associated with sustained perinatal depression. Participation in the PMTCT intervention was associated with remitting depression while alcohol use was associated with the onset of postnatal depression. Using generalized linear mixed models in longitudinal analyses, psychological partner violence, lack of male involvement during pregnancy and non-adherence to antiretroviral treatment were associated with depression. In conclusion, a high pre- and postnatal prevalence of depression was found highlighting the utility of interventions to address prevention and treatment of perinatal depression. FAU - Peltzer, Karl AU - Peltzer K AUID- ORCID: 0000-0002-5980-0876 AD - a HIV/AIDS/STIs and TB (HAST) Research Programme , Human Sciences Research Council , Pretoria , South Africa. AD - b Department of Research & Innovation , University of Limpopo , Sovenga , South Africa. FAU - Rodriguez, Violeta J AU - Rodriguez VJ AD - c Department of Psychiatry & Behavioral Sciences , University of Miami Miller School of Medicine , Miami , USA. AD - d Department of Psychology , University of Georgia. FAU - Lee, Tae Kyoung AU - Lee TK AD - e Department of Public Health Sciences , University of Miami Miller School of Medicine. FAU - Jones, Deborah AU - Jones D AUID- ORCID: 0000-0002-4106-8891 AD - c Department of Psychiatry & Behavioral Sciences , University of Miami Miller School of Medicine , Miami , USA. LA - eng GR - K23 HD074489/HD/NICHD NIH HHS/United States GR - P30 AI073961/AI/NIAID NIH HHS/United States GR - R01 HD078187/HD/NICHD NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural DEP - 20180325 PL - England TA - AIDS Care JT - AIDS care JID - 8915313 SB - IM MH - Adolescent MH - Adult MH - Depression, Postpartum/*epidemiology MH - Female MH - HIV Infections/*epidemiology/*psychology MH - Humans MH - Infectious Disease Transmission, Vertical/prevention & control MH - Longitudinal Studies MH - Pregnancy MH - Prevalence MH - *Rural Population MH - South Africa/epidemiology PMC - PMC6150830 MID - NIHMS955069 OTO - NOTNLM OT - Antenatal care OT - HIV OT - South Africa OT - depression OT - longitudinal study OT - postnatal care COIS- Disclosure statement No potential conflict of interest was reported by the authors. EDAT- 2018/03/27 06:00 MHDA- 2019/10/01 06:00 PMCR- 2019/11/01 CRDT- 2018/03/27 06:00 PHST- 2018/03/27 06:00 [pubmed] PHST- 2019/10/01 06:00 [medline] PHST- 2018/03/27 06:00 [entrez] PHST- 2019/11/01 00:00 [pmc-release] AID - 10.1080/09540121.2018.1455960 [doi] PST - ppublish SO - AIDS Care. 2018 Nov;30(11):1372-1379. doi: 10.1080/09540121.2018.1455960. Epub 2018 Mar 25.