PMID- 29576253 OWN - NLM STAT- MEDLINE DCOM- 20181106 LR - 20181106 IS - 1769-664X (Electronic) IS - 0929-693X (Linking) VI - 25 IP - 3 DP - 2018 Apr TI - Nutritional management of cow's milk allergy in children: An update. PG - 236-243 LID - S0929-693X(18)30050-2 [pii] LID - 10.1016/j.arcped.2018.01.007 [doi] AB - Cow's milk is one of the most common foods responsible for allergic reactions in children. Cow's milk allergy (CMA) involves immunoglobulin E (IgE)- and non-IgE-mediated reactions, the latter being both variable and nonspecific. Guidelines thus emphasize the need for physicians to recognize the specific syndromes of CMA and to respect strict diagnostic modalities. Whatever the clinical pattern of CMA, the mainstay of treatment is the elimination from the diet of cow's milk proteins. The challenge is that both the disease and the elimination diet may result in insufficient height and weight gain and bone mineralization. If, during CMA, the mother is not able or willing to breastfeed, the child must be fed a formula adapted to CMA dietary management, during infancy and later, if the disease persists. This type of formula must be adequate in terms of allergic efficacy and nutritional safety. In older children, when CMA persists, the use of cow's milk baked or heated at a sufficient temperature, frequently tolerated by children with CMA, may help alleviate the stringency of the elimination diet. Guidance on the implementation of the elimination diet by qualified healthcare professionals is always necessary. This guidance should also include advice to ensure adequate bone growth, especially relating to calcium intake. Specific attention should be given to children presenting with several risk factors for weak bone mineral density, i.e., multiple food allergies, vitamin D deficiency, poor sun exposure, steroid use, or severe eczema. When CMA is outgrown, a prolonged elimination diet may negatively impact the quality of the diet over the long term. CI - Copyright (c) 2018 Elsevier Masson SAS. All rights reserved. FAU - Dupont, C AU - Dupont C AD - Universite Paris Descartes, 75006 Paris, France. Electronic address: christophe.dupont@aphp.fr. FAU - Chouraqui, J-P AU - Chouraqui JP AD - Universite Joseph-Fourier, 38000 Grenoble, France. FAU - Linglart, A AU - Linglart A AD - Service d'endocrinologie-diabete de l'enfant, CHU de Bicetre, 94275 Kremlin-Bicetre, France. FAU - Bocquet, A AU - Bocquet A AD - Universite de Franche-Comte, 25000 Besancon, France. FAU - Darmaun, D AU - Darmaun D AD - Universite Nantes-Atlantique, 44300 Nantes, France. FAU - Feillet, F AU - Feillet F AD - Universite de Lorraine, 54000 Nancy, France. FAU - Frelut, M-L AU - Frelut ML AD - Endocrinologie-diabete de l'enfant, CHU de Bicetre, 94270 Le Kremlin-Bicetre, France. FAU - Girardet, J-P AU - Girardet JP AD - Universite Pierre-et-Marie-Curie Paris-6, 75005 Paris, France. FAU - Hankard, R AU - Hankard R AD - Inserm U 1069, universite de Tours, CHU de Tours, 37000 Tours, France. FAU - Roze, J-C AU - Roze JC AD - Universite Nantes-Atlantique, 44300 Nantes, France. FAU - Simeoni, U AU - Simeoni U AD - Universite de Lausanne, 1011 Lausanne, Switzerland. FAU - Briend, A AU - Briend A AD - Institut de recherche pour le developpement, 13572 Marseille, France. CN - Committee on Nutrition of the French Society of Pediatrics LA - eng PT - Journal Article DEP - 20180322 PL - France TA - Arch Pediatr JT - Archives de pediatrie : organe officiel de la Societe francaise de pediatrie JID - 9421356 SB - IM MH - Animals MH - Bone Diseases, Metabolic/prevention & control MH - Breast Feeding MH - Cooking MH - Dietary Services MH - Growth Disorders/etiology/prevention & control MH - Humans MH - Infant MH - Infant Formula MH - Milk Hypersensitivity/immunology/*therapy MH - Practice Guidelines as Topic MH - Risk Factors OTO - NOTNLM OT - Allergy OT - Baked milk OT - Cow's milk OT - Enterocolitis OT - Eosinophilic esophagitis OT - Nutrition EDAT- 2018/03/27 06:00 MHDA- 2018/11/07 06:00 CRDT- 2018/03/27 06:00 PHST- 2018/01/13 00:00 [received] PHST- 2018/01/29 00:00 [accepted] PHST- 2018/03/27 06:00 [pubmed] PHST- 2018/11/07 06:00 [medline] PHST- 2018/03/27 06:00 [entrez] AID - S0929-693X(18)30050-2 [pii] AID - 10.1016/j.arcped.2018.01.007 [doi] PST - ppublish SO - Arch Pediatr. 2018 Apr;25(3):236-243. doi: 10.1016/j.arcped.2018.01.007. Epub 2018 Mar 22.