PMID- 29576791
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 1741-427X (Print)
IS  - 1741-4288 (Electronic)
IS  - 1741-427X (Linking)
VI  - 2018
DP  - 2018
TI  - A Systematic Review about the Efficacy and Safety of Tripterygium wilfordii 
      Hook.f. Preparations Used for the Management of Rheumatoid Arthritis.
PG  - 1567463
LID - 10.1155/2018/1567463 [doi]
LID - 1567463
AB  - Tripterygium wilfordii Hook.f. (TWHF) is a traditional Chinese herb long used for 
      rheumatoid arthritis (RA) treatment, in modern times, often in the form of 
      various Tripterygium wilfordii Hook.f. preparations (TWPs). This systematic 
      review and meta-analysis focuses on analyzing the clinical efficacy and safety of 
      TWPs in the treatment of RA. Databases were searched to collect the randomized 
      controlled trials (RCTs) on TWPs treating RA published on or before April 10, 
      2017. Data from 11 studies were included in this meta-analysis. Compared with the 
      control group, TWPs can increase effectiveness, while decreasing erythrocyte 
      sedimentation rate (ESR), rheumatoid factor (RF), C-reactive protein (CRP), and 
      risk of adverse events. TWPs treatment was also more effective than treatment by 
      conventional western medicine (CWM) and Chinese patent medicine or placebo (COP). 
      TWPs significantly decreased the risk of adverse events compared with the CWM 
      group, but not compared with the COP group. Current evidence shows that TWPs are 
      more effective than other western or Chinese medicines we included in this 
      meta-analysis for RA treatment with relatively lower toxicity.
FAU - Wang, Jing
AU  - Wang J
AUID- ORCID: 0000-0003-4971-7769
AD  - The First Clinical Medical College, Nanjing University of Chinese Medicine, 
      Nanjing 210023, China.
FAU - Chen, Na
AU  - Chen N
AD  - School of Health Economics and Management, Nanjing University of Chinese 
      Medicine, Nanjing 210023, China.
FAU - Fang, Liang
AU  - Fang L
AD  - The First Clinical Medical College, Nanjing University of Chinese Medicine, 
      Nanjing 210023, China.
FAU - Feng, Zhe
AU  - Feng Z
AD  - The First Clinical Medical College, Nanjing University of Chinese Medicine, 
      Nanjing 210023, China.
FAU - Li, Guochun
AU  - Li G
AD  - College of Medicine and Life Sciences, Nanjing University of Chinese Medicine, 
      Nanjing 210023, China.
FAU - Mucelli, Attilio
AU  - Mucelli A
AUID- ORCID: 0000-0002-9036-2579
AD  - Department of Management, School of Economics "Giorgio Fua", Universita 
      Politecnica delle Marche, No. 8, 60121 Ancona, Italy.
FAU - Zhang, Xu
AU  - Zhang X
AUID- ORCID: 0000-0002-1959-1758
AD  - Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine (TCM) 
      Prevention and Treatment of Tumor, Nanjing University of Chinese Medicine, 
      Nanjing 210023, China.
FAU - Zhou, Xueping
AU  - Zhou X
AUID- ORCID: 0000-0001-7807-9968
AD  - The First Clinical Medical College, Nanjing University of Chinese Medicine, 
      Nanjing 210023, China.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20180208
PL  - United States
TA  - Evid Based Complement Alternat Med
JT  - Evidence-based complementary and alternative medicine : eCAM
JID - 101215021
PMC - PMC5822783
EDAT- 2018/03/27 06:00
MHDA- 2018/03/27 06:01
PMCR- 2018/02/08
CRDT- 2018/03/27 06:00
PHST- 2017/08/30 00:00 [received]
PHST- 2017/11/22 00:00 [revised]
PHST- 2017/12/19 00:00 [accepted]
PHST- 2018/03/27 06:00 [entrez]
PHST- 2018/03/27 06:00 [pubmed]
PHST- 2018/03/27 06:01 [medline]
PHST- 2018/02/08 00:00 [pmc-release]
AID - 10.1155/2018/1567463 [doi]
PST - epublish
SO  - Evid Based Complement Alternat Med. 2018 Feb 8;2018:1567463. doi: 
      10.1155/2018/1567463. eCollection 2018.