PMID- 29579639
OWN - NLM
STAT- MEDLINE
DCOM- 20190322
LR  - 20190322
IS  - 1876-7753 (Electronic)
IS  - 1873-5061 (Linking)
VI  - 29
DP  - 2018 May
TI  - Generation of a human induced pluripotent stem cell line (VRFi001-A) from orbital 
      adipose tissue of a bilateral retinoblastoma patient with heterozygous RB1 gene 
      deletion.
PG  - 42-45
LID - S1873-5061(18)30090-4 [pii]
LID - 10.1016/j.scr.2018.03.012 [doi]
AB  - Retinoblastoma (RB) is a pediatric intraocular tumor caused by mutations in 
      retinoblastoma (RB1) gene. We have generated induced pluripotent stem cell line 
      VRFi001-A from a bilateral retinoblastoma patient with heterozygous RB1 gene 
      deletion. The iPSC line VRFi001-A retained the mutation and expressed 
      pluripotency markers, had a normal karyotype and was capable of trilineage 
      differentiation.
CI  - Copyright (c) 2018 The Authors. Published by Elsevier B.V. All rights reserved.
FAU - Vincent, Ambily
AU  - Vincent A
AD  - Radheshyam Kanoi Stem Cell Laboratory, Kamalnayan Bajaj Institute for Research in 
      Vision and Ophthalmology, Vision Research Foundation, Chennai, India; School of 
      Chemical and Biotechnology, SASTRA Deemed-to-be University, Thanjavur, India.
FAU - Khetan, Vikas
AU  - Khetan V
AD  - Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Medical Research 
      Foundation, Chennai, India.
FAU - Rishi, Pukhraj
AU  - Rishi P
AD  - Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Medical Research 
      Foundation, Chennai, India.
FAU - Suganeswari, Ganesan
AU  - Suganeswari G
AD  - Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Medical Research 
      Foundation, Chennai, India.
FAU - Krishnakumar, Subramanian
AU  - Krishnakumar S
AD  - Radheshyam Kanoi Stem Cell Laboratory, Kamalnayan Bajaj Institute for Research in 
      Vision and Ophthalmology, Vision Research Foundation, Chennai, India.
FAU - Krishnan, Uma Maheswari
AU  - Krishnan UM
AD  - School of Chemical and Biotechnology, SASTRA Deemed-to-be University, Thanjavur, 
      India.
FAU - Parameswaran, Sowmya
AU  - Parameswaran S
AD  - Radheshyam Kanoi Stem Cell Laboratory, Kamalnayan Bajaj Institute for Research in 
      Vision and Ophthalmology, Vision Research Foundation, Chennai, India. Electronic 
      address: drpsowmya@snmail.org.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180319
PL  - England
TA  - Stem Cell Res
JT  - Stem cell research
JID - 101316957
RN  - 0 (Retinoblastoma Protein)
SB  - IM
MH  - Adipose Tissue/*metabolism
MH  - Cell Line
MH  - Child
MH  - Gene Deletion
MH  - Humans
MH  - Induced Pluripotent Stem Cells/*metabolism
MH  - Orbit/*metabolism/pathology
MH  - Retinoblastoma/*genetics
MH  - Retinoblastoma Protein/*genetics
EDAT- 2018/03/27 06:00
MHDA- 2019/03/23 06:00
CRDT- 2018/03/27 06:00
PHST- 2018/02/22 00:00 [received]
PHST- 2018/03/05 00:00 [revised]
PHST- 2018/03/16 00:00 [accepted]
PHST- 2018/03/27 06:00 [pubmed]
PHST- 2019/03/23 06:00 [medline]
PHST- 2018/03/27 06:00 [entrez]
AID - S1873-5061(18)30090-4 [pii]
AID - 10.1016/j.scr.2018.03.012 [doi]
PST - ppublish
SO  - Stem Cell Res. 2018 May;29:42-45. doi: 10.1016/j.scr.2018.03.012. Epub 2018 Mar 
      19.