PMID- 29582597
OWN - NLM
STAT- MEDLINE
DCOM- 20181004
LR  - 20181004
IS  - 1872-2059 (Electronic)
IS  - 1000-8713 (Linking)
VI  - 36
IP  - 2
DP  - 2018 Feb 8
TI  - [Rapid determination of 25 drug residues in aquatic products by ultra performance 
      liquid chromatography-quadrupole/electrostatic field orbitrap high resolution 
      mass spectrometry].
PG  - 114-124
LID - 10.3724/SP.J.1123.2017.10010 [doi]
AB  - An ultra performance liquid chromatography-quadrupole/electrostatic field 
      orbitrap high resolution mass spectrometry (UPLC-Q Orbitrap HRMS) method was 
      developed for the rapid screening of 25 drug residues in aquatic products by the 
      application of a novel enhanced matrix removal of lipids (EMR-Lipid). The samples 
      were extracted with acetonitrile, cleaned-up with EMR-Lipid, and salted out with 
      3.0 g sodium chloride and 3.0 g sodium sulfate. The separation of the 25 drug 
      residues was performed on an ACQUITY UPLC BEH C18 column (100 mmx2.1 mm, 1.7 mum) 
      with gradient elution. Acetonitrile containing 0.1% (v/v) formic acid and 0.1% 
      (v/v) formic acid aqueous solution were used as mobile phases. The compounds were 
      detected by Full scan/date dependent MS/MS (Full MS/dd-MS(2)) via heated 
      electrospray ionization (HESI) source. The calibration curves were linear with 
      correlation coefficients (r) greater than 0.997. The limits of detection (LODs) 
      ranged from 0.1 mug/kg to 1.0 mug/kg. The average spiked recoveries of the 25 
      target compounds were between 70.1% and 108.9% with relative standard derivations 
      (RSDs) from 2.1% to 13.8%. Compared with the previous methods, this method has 
      characteristics of simpler sample preparation and higher sensitivity.
FAU - Zhang, Xianchen
AU  - Zhang X
AD  - Inspection and Quarantine Technology Center of Zhongshan Entry-Exit Inspection 
      and Quarantine Bureau, Zhongshan 528403, China. zhangxc@zs.gdciq.gov.cn.
FAU - Li, Rong
AU  - Li R
AD  - Inspection and Quarantine Technology Center of Zhongshan Entry-Exit Inspection 
      and Quarantine Bureau, Zhongshan 528403, China.
FAU - Zhang, Pengjie
AU  - Zhang P
AD  - Inspection and Quarantine Technology Center of Zhongshan Entry-Exit Inspection 
      and Quarantine Bureau, Zhongshan 528403, China.
FAU - Wu, Xia
AU  - Wu X
AD  - Agilent Technologies Co., Ltd. (China), Guangzhou 510000, China.
FAU - Hua, Hongbo
AU  - Hua H
AD  - Zhongshan ZhuoYa Foreign Language School, Zhongshan 528401, China.
FAU - Yang, Luqi
AU  - Yang L
AD  - Inspection and Quarantine Technology Center of Zhongshan Entry-Exit Inspection 
      and Quarantine Bureau, Zhongshan 528403, China.
FAU - Lu, Junwen
AU  - Lu J
AD  - Inspection and Quarantine Technology Center of Zhongshan Entry-Exit Inspection 
      and Quarantine Bureau, Zhongshan 528403, China.
FAU - Rong, Yutang
AU  - Rong Y
AD  - Inspection and Quarantine Technology Center of Zhongshan Entry-Exit Inspection 
      and Quarantine Bureau, Zhongshan 528403, China.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
SB  - IM
MH  - Calibration
MH  - *Chromatography, High Pressure Liquid
MH  - Drug Residues/*analysis
MH  - Limit of Detection
MH  - *Mass Spectrometry
MH  - Seafood/*analysis
OTO - NOTNLM
OT  - QuEChERS
OT  - aquatic products
OT  - drug residues
OT  - enhanced matrix removal of lipids (EMR-Lipid)
OT  - quadrupole/electrostatic field orbitrap high resolution mass spectrometry (Q 
      Orbitrap HRMS)
OT  - ultra performance liquid chromatography (UPLC)
EDAT- 2018/03/28 06:00
MHDA- 2018/10/05 06:00
CRDT- 2018/03/28 06:00
PHST- 2018/03/28 06:00 [entrez]
PHST- 2018/03/28 06:00 [pubmed]
PHST- 2018/10/05 06:00 [medline]
AID - 10.3724/SP.J.1123.2017.10010 [doi]
PST - ppublish
SO  - Se Pu. 2018 Feb 8;36(2):114-124. doi: 10.3724/SP.J.1123.2017.10010.