PMID- 29582601
OWN - NLM
STAT- MEDLINE
DCOM- 20181004
LR  - 20181004
IS  - 1872-2059 (Electronic)
IS  - 1000-8713 (Linking)
VI  - 36
IP  - 2
DP  - 2018 Feb 8
TI  - [Determination of sedative and beta-receptor hormone residues in feed by ultra high 
      performance liquid chromatography-tandem mass spectrometry].
PG  - 150-158
LID - 10.3724/SP.J.1123.2017.10025 [doi]
AB  - An analysis and detection method for eight sedatives and fifteen beta-receptor 
      hormones in feed was established by ultra high performance liquid 
      chromatography-tandem mass spectrometry (UHPLC-MS/MS). The sample was extracted 
      with acetonitrile-1% (v/v) trichloroacetic acid aqueous solution (7:3, v/v), and 
      purified by cationic solid phase extraction column. The extracts were separated 
      on an Agilent Zorbax Eclipse Plus C(18) chromatographic column (100 mmx3.0 mm, 
      1.8 mum) and then quantified via internal standard method. The results showed that 
      the linear relationships of the 23 targets were good in the range of 2.0-200.0 
      mug/L (r(2)> 0.99). The average recoveries of the targets spiked in the matrix of 
      feed samples were within 75.1%-102.4% in three spiked levels of 5.0, 10, 50 
      mug/kg, and the relative standard deviations (RSDs) were within 4.3%-14.3% (n=6). 
      This method with high purification efficiency and extensive scope of application 
      can be applied to screening and detecting sedatives and beta -receptor hormones in 
      feed.
FAU - Sun, Shanshan
AU  - Sun S
AD  - College of Pharmacy, Liaoning University, Shenyang 110036, China.
FAU - Zhu, Lijun
AU  - Zhu L
AD  - College of Pharmacy, Liaoning University, Shenyang 110036, China.
FAU - Hu, Yanxi
AU  - Hu Y
AD  - College of Pharmacy, Liaoning University, Shenyang 110036, China.
FAU - Liu, Yufeng
AU  - Liu Y
AD  - College of Pharmacy, Liaoning University, Shenyang 110036, China.
AD  - Natural Products Pharmaceutical Engineering Technology Research Center of 
      Liaoning Province, Shenyang 110036, China. liuyufeng@bjmu.edu.cn.
FAU - Xu, Liang
AU  - Xu L
AD  - College of Pharmacy, Liaoning University, Shenyang 110036, China.
AD  - Natural Products Pharmaceutical Engineering Technology Research Center of 
      Liaoning Province, Shenyang 110036, China. liuyufeng@bjmu.edu.cn.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Hormones)
RN  - 0 (Hypnotics and Sedatives)
SB  - IM
MH  - Animal Feed/*analysis
MH  - *Chromatography, High Pressure Liquid
MH  - Chromatography, Liquid
MH  - Hormones/*analysis
MH  - Hypnotics and Sedatives/*analysis
MH  - Solid Phase Extraction
MH  - *Tandem Mass Spectrometry
OTO - NOTNLM
OT  - cationic solid phase extraction column
OT  - feed
OT  - sedative and beta-receptor hormone
OT  - ultra high performance liquid chromatography-tandem mass spectrometry 
      (UHPLC-MS/MS)
EDAT- 2018/03/28 06:00
MHDA- 2018/10/05 06:00
CRDT- 2018/03/28 06:00
PHST- 2018/03/28 06:00 [entrez]
PHST- 2018/03/28 06:00 [pubmed]
PHST- 2018/10/05 06:00 [medline]
AID - 10.3724/SP.J.1123.2017.10025 [doi]
PST - ppublish
SO  - Se Pu. 2018 Feb 8;36(2):150-158. doi: 10.3724/SP.J.1123.2017.10025.