PMID- 29587189
OWN - NLM
STAT- MEDLINE
DCOM- 20190204
LR  - 20190215
IS  - 1873-2682 (Electronic)
IS  - 1011-1344 (Linking)
VI  - 182
DP  - 2018 May
TI  - Synthesis of NiO nanoparticles via a green route using Monsonia burkeana: The 
      physical and biological properties.
PG  - 18-26
LID - S1011-1344(18)30122-2 [pii]
LID - 10.1016/j.jphotobiol.2018.03.016 [doi]
AB  - NiO nanoparticles have emerged as ideal candidates in various fields due to their 
      magnetic, electrical and optical properties. The coupling of plant extracts that 
      have anticancer and antibacterial properties with NiO nanoparticles has increased 
      their usage in the biomedical field. In this work, we report on the novel 
      synthesis of NiO nanoparticles using a local medicinal plant, Monsonia burkenea. 
      The nickel nanoparticles were characterized using Fourier transform infrared 
      spectroscopy (FTIR), Energy dispersive X-ray analysis (EDX), Scanning electron 
      microscope (SEM), High-resolution transmission electron microscope (HRTEM) and 
      X-ray diffraction (XRD). FTIR showed that the extraction of the plant 
      phytochemicals was successful and the green synthesized nanoparticles from plants 
      contained the phytochemical groups that are found in the Monsonia burkeana plant. 
      XRD and HRTEM confirmed the successful formation of NiO nanoparticles with an 
      average particle size range of 20 nm. These results were also corroborated by 
      elemental mapping and EDX, where the dominant groups were identified.The Monsonia 
      burkeana NiO particles exhibited selective bactericidal activity against 
      Gram-negative strains, such as E. coli and P. aeruginosa. Additionally, 
      cytotoxicity studies showed the materials did not have any anti proliferative 
      effect against A549 lung cancer cells but could be used as potential drug 
      delivery vehicles against human cancers.
CI  - Copyright (c) 2018 Elsevier B.V. All rights reserved.
FAU - Kganyago, P
AU  - Kganyago P
AD  - Department of Chemistry, University of Limpopo, Sovenga, Polokwane 0727, South 
      Africa.
FAU - Mahlaule-Glory, L M
AU  - Mahlaule-Glory LM
AD  - Department of Chemistry, University of Limpopo, Sovenga, Polokwane 0727, South 
      Africa.
FAU - Mathipa, M M
AU  - Mathipa MM
AD  - Limpopo Agro-Food Technology Station, University of Limpopo, Sovenga, Polokwane 
      0727, South Africa.
FAU - Ntsendwana, B
AU  - Ntsendwana B
AD  - Nanotechnology and Water Sustainability Research Unit, Science Campus, University 
      of South Africa, Rooderpoort, Johannesburg 1710, South Africa.
FAU - Mketo, N
AU  - Mketo N
AD  - Department of Chemistry, College of Science Engineering and Technology, 
      University of South Africa, Private Bag X3, Johannesburg, South Africa.
FAU - Mbita, Z
AU  - Mbita Z
AD  - Department of Biochemistry, Microbiology and Biotechnology, University of 
      Limpopo, Sovenga, Polokwane 0727, South Africa.
FAU - Hintsho-Mbita, N C
AU  - Hintsho-Mbita NC
AD  - Department of Chemistry, University of Limpopo, Sovenga, Polokwane 0727, South 
      Africa; DST/NRF Centre of Excellence in Strong Materials, South Africa. 
      Electronic address: nomso.hintsho-mbita@ul.ac.za.
LA  - eng
PT  - Journal Article
DEP - 20180321
PL  - Switzerland
TA  - J Photochem Photobiol B
JT  - Journal of photochemistry and photobiology. B, Biology
JID - 8804966
RN  - 0 (Anti-Infective Agents)
RN  - 7OV03QG267 (Nickel)
RN  - C3574QBZ3Y (nickel monoxide)
SB  - IM
MH  - A549 Cells
MH  - Anti-Infective Agents/chemistry/pharmacology/toxicity
MH  - Cell Survival/drug effects
MH  - Escherichia coli/drug effects
MH  - Geraniaceae/*metabolism
MH  - *Green Chemistry Technology
MH  - HEK293 Cells
MH  - Humans
MH  - Metal Nanoparticles/*chemistry/toxicity
MH  - Nickel/*chemistry
MH  - Particle Size
MH  - Spectroscopy, Fourier Transform Infrared
MH  - X-Ray Diffraction
OTO - NOTNLM
OT  - Bacterial strains
OT  - Green chemistry
OT  - Monsonia burkeana
OT  - NiO nanoparticles
OT  - Toxicity
EDAT- 2018/03/28 06:00
MHDA- 2019/02/05 06:00
CRDT- 2018/03/28 06:00
PHST- 2018/02/02 00:00 [received]
PHST- 2018/03/06 00:00 [revised]
PHST- 2018/03/19 00:00 [accepted]
PHST- 2018/03/28 06:00 [pubmed]
PHST- 2019/02/05 06:00 [medline]
PHST- 2018/03/28 06:00 [entrez]
AID - S1011-1344(18)30122-2 [pii]
AID - 10.1016/j.jphotobiol.2018.03.016 [doi]
PST - ppublish
SO  - J Photochem Photobiol B. 2018 May;182:18-26. doi: 
      10.1016/j.jphotobiol.2018.03.016. Epub 2018 Mar 21.