PMID- 29590256
OWN - NLM
STAT- MEDLINE
DCOM- 20180425
LR  - 20181202
IS  - 1414-431X (Electronic)
IS  - 0100-879X (Print)
IS  - 0100-879X (Linking)
VI  - 51
IP  - 5
DP  - 2018 Mar 26
TI  - Unsteady walking as a symptom in type 2 diabetes mellitus: independent 
      association with depression and sedentary lifestyle and no association with 
      diabetic neuropathy.
PG  - e6605
LID - S0100-879X2018000500613 [pii]
LID - 10.1590/1414-431X20186605 [doi]
LID - e6605
AB  - The purpose of this study was to look at the determinants of the unsteady walking 
      (UW) symptom in patients with type 2 diabetes mellitus (T2DM) by defining if UW 
      and/or the Diabetic Neuropathy Symptoms Score (DNSS) are associated with positive 
      scores in Beck's Depression Inventory (BDI) and with a positive Michigan 
      Neuropathy Screening Instrument score (MNSI). We evaluated 203 T2DM patients 
      without visible gait disturbances. They were divided into UW (+) and UW (-) or 
      DNSS (+) and DNSS (-) according to symptoms. We found a prevalence of 48.3% for 
      UW (+) and of 63% for DNSS (+) in our sample. In univariate analysis, the 
      presence of UW was significantly associated with waist circumference (P=0.024), 
      number of comorbidities (P=0.012), not practicing physical exercise (P=0.011), 
      positive BDI score (P=0.003), presence of neuropathic symptoms by the MNSI 
      questionnaire (P<0.001), and positive diabetic neuropathy screening by MNSI 
      (P=0.021). In multivariate analysis, UW (used as a dependent variable) was 
      independently associated with a positive BDI score (P<0.001; 95%CI=1.01-1.03), 
      T2DM duration (P=0.023; 95%CI=1.00-1.03), number of co-morbidities (P=0.032; 
      95%CI=1.01-1.37), and a sedentary lifestyle (P=0.025; 95%CI=1.06-2.5). The UW 
      symptom and a positive DNSS are more closely related to a positive score for 
      depression than to presence of neuropathy in T2DM.
FAU - Dias, L S
AU  - Dias LS
AD  - Programa de Pos-Graduacao em Ciencias da Saude, Ginecologia e Obstetricia, 
      Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, 
      RS, Brasil.
AD  - Programa de Pos-Graduacao em Ciencias da Saude, Universidade Federal de Ciencias 
      da Saude de Porto Alegre, Porto Alegre, RS, Brasil.
FAU - Nienov, O H
AU  - Nienov OH
AD  - Programa de Pos-Graduacao em Ciencias da Saude, Ginecologia e Obstetricia, 
      Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, 
      RS, Brasil.
FAU - Goelzer Neto, C F
AU  - Goelzer Neto CF
AD  - Programa de Pos-Graduacao em Ciencias da Saude, Universidade Federal de Ciencias 
      da Saude de Porto Alegre, Porto Alegre, RS, Brasil.
FAU - Schmid, H
AU  - Schmid H
AD  - Programa de Pos-Graduacao em Ciencias da Saude, Ginecologia e Obstetricia, 
      Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, 
      RS, Brasil.
AD  - Programa de Pos-Graduacao em Ciencias da Saude, Universidade Federal de Ciencias 
      da Saude de Porto Alegre, Porto Alegre, RS, Brasil.
AD  - Servico de Endocrinologia, Hospital Santa Casa de Misericordia de Porto Alegre, 
      Porto Alegre, RS, Brasil.
AD  - Departamento de Medicina Interna, Hospital de Clinicas de Porto Alegre, Porto 
      Alegre, RS, Brasil.
LA  - eng
PT  - Journal Article
DEP - 20180326
PL  - Brazil
TA  - Braz J Med Biol Res
JT  - Brazilian journal of medical and biological research = Revista brasileira de 
      pesquisas medicas e biologicas
JID - 8112917
SB  - IM
MH  - Cross-Sectional Studies
MH  - Depression/*psychology
MH  - Diabetes Mellitus, Type 2/*complications
MH  - Diabetic Neuropathies/*complications/physiopathology/psychology
MH  - Female
MH  - Humans
MH  - Male
MH  - Mass Screening
MH  - Middle Aged
MH  - Prevalence
MH  - *Sedentary Behavior
MH  - Sensation Disorders/*etiology
MH  - Severity of Illness Index
MH  - Walking/*physiology
PMC - PMC5886546
EDAT- 2018/03/29 06:00
MHDA- 2018/04/26 06:00
PMCR- 2018/03/26
CRDT- 2018/03/29 06:00
PHST- 2017/07/15 00:00 [received]
PHST- 2018/01/04 00:00 [accepted]
PHST- 2018/03/29 06:00 [entrez]
PHST- 2018/03/29 06:00 [pubmed]
PHST- 2018/04/26 06:00 [medline]
PHST- 2018/03/26 00:00 [pmc-release]
AID - S0100-879X2018000500613 [pii]
AID - 10.1590/1414-431X20186605 [doi]
PST - epublish
SO  - Braz J Med Biol Res. 2018 Mar 26;51(5):e6605. doi: 10.1590/1414-431X20186605.