PMID- 29594811
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20190122
LR  - 20190122
IS  - 1436-5073 (Electronic)
IS  - 0026-3672 (Linking)
VI  - 185
IP  - 2
DP  - 2018 Jan 27
TI  - A regenerable sorbent composed of a zeolite imidazolate framework (ZIF-8), 
      Fe(3)O(4) and graphene oxide for enrichment of atorvastatin and simvastatin prior 
      to their determination by HPLC.
PG  - 141
LID - 10.1007/s00604-018-2697-6 [doi]
AB  - Graphene oxide (GO), nanosized Fe(3)O(4) and zeolite imidazolate framework-8 
      (ZIF-8) were hybridized as a multifunctional sorbent for use in microextraction. 
      The sorbent was characterized by SEM, TEM, XRD and FTIR. The composite is porous, 
      has a high specific surface (> 600 m(2).g(-1)) and is paramagnetic. The GO sheets 
      are shown to act as carriers for the Fe(3)O(4) nanoparticles and ZIF-8. The 
      composite is a viable material for the preconcentration of atorvastatin and 
      simvastatin from urine prior to their determination by HPLC with PDA detection. 
      The limits of detection are 116 and 387 pg.mL(-1), respectively. Recoveries from 
      spiked urine samples range between 84.7 and 95.7%, with relative standard 
      deviation of </=4.5%. Enrichment factors range from 169 to 191. The method was 
      successfully applied to the determination of atorvastatin in urine. Moreover, 
      this sorbent is regenerable and recyclable for at least seven times without 
      obvious decrease in performance. Graphical abstract A composite sorbent composed 
      of a zeolite imidazolate framework, Fe(3)O(4) and graphene oxide was applied to 
      the extraction of statins in urine prior their determination by HPLC.
FAU - Peng, Jun
AU  - Peng J
AD  - Key Laboratory of Biomedical Functional Materials, China Pharmaceutical 
      University, Nanjing, 211198, China.
AD  - Department of Analytical Chemistry, China Pharmaceutical University, Nanjing, 
      211198, China.
FAU - Tian, Huairu
AU  - Tian H
AD  - Department of Analytical Chemistry, China Pharmaceutical University, Nanjing, 
      211198, China.
FAU - Du, Qiuzheng
AU  - Du Q
AD  - Key Laboratory of Biomedical Functional Materials, China Pharmaceutical 
      University, Nanjing, 211198, China.
AD  - Department of Analytical Chemistry, China Pharmaceutical University, Nanjing, 
      211198, China.
FAU - Hui, Xuanhong
AU  - Hui X
AD  - Department of Analytical Chemistry, China Pharmaceutical University, Nanjing, 
      211198, China.
FAU - He, Hua
AU  - He H
AD  - Key Laboratory of Biomedical Functional Materials, China Pharmaceutical 
      University, Nanjing, 211198, China. jcb_321@163.com.
AD  - Department of Analytical Chemistry, China Pharmaceutical University, Nanjing, 
      211198, China. jcb_321@163.com.
AD  - Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of 
      Education, China Pharmaceutical University, 24 Tongjia Lane, Nanjing, Jiangsu 
      Province, 211198, China. jcb_321@163.com.
LA  - eng
GR  - CX (17)1003/Independent Innovation Fund Project of Agricultural Science and 
      Technology of Jiangsu Province/International
GR  - 7076/Guizhou Provincial Science and Technology Department Joint Fund 
      Project/International
GR  - 2015026/Project Funded by Research Project of Environment Protection Department 
      of Jiangsu Province/International
GR  - J1310032/Chinese College Students Innovation Project for the R&amp;D of Novel 
      Drugs/International
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180127
PL  - Austria
TA  - Mikrochim Acta
JT  - Mikrochimica acta
JID - 7808782
OTO - NOTNLM
OT  - Chromatographic analysis
OT  - Functional composite
OT  - Magnetic separation
OT  - Metal-organic framework
OT  - Sample preparation
OT  - Solid phase microextraction
OT  - Urine samples
EDAT- 2018/03/30 06:00
MHDA- 2018/03/30 06:01
CRDT- 2018/03/30 06:00
PHST- 2017/10/22 00:00 [received]
PHST- 2018/01/20 00:00 [accepted]
PHST- 2018/03/30 06:00 [entrez]
PHST- 2018/03/30 06:00 [pubmed]
PHST- 2018/03/30 06:01 [medline]
AID - 10.1007/s00604-018-2697-6 [pii]
AID - 10.1007/s00604-018-2697-6 [doi]
PST - epublish
SO  - Mikrochim Acta. 2018 Jan 27;185(2):141. doi: 10.1007/s00604-018-2697-6.