PMID- 2960035 OWN - NLM STAT- MEDLINE DCOM- 19871124 LR - 20131121 IS - 0385-0005 (Print) IS - 0385-0005 (Linking) VI - 11 IP - 5 DP - 1986 Nov TI - Clinical effect of dipyridamole in patients with IgA nephropathy. PG - 329-33 AB - Clinical effects of dipyridamole and carbazochrome sodium sulfonate in patients with IgA nephropathy are described. Oral administration of 300 mg of dipyridamole and 180 mg of carbazochrome sodium sulfonate per day was employed in the present study. Urinalysis and renal function tests, i.e. serum creatinine (s-Cr), blood urea nitrogen (BUN), glomerular filtration rate (GFR) and phenolsulfonphtalein (PSP) tests, were performed before and after the administration of dipyridamole. It was demonstrated that the administration of dipyridamole was effective in reducing the level of proteinuria in the patients. The administration of carbazochrome sodium sulfonate was not effective in reducing the proteinuria level. It was concluded that the administration of dipyridamole may be useful for treatment of patients with IgA nephropathy. FAU - Yagame, M AU - Yagame M AD - Department of Internal Medicine, School of Medicine, Tokai University, Japan. FAU - Tomino, Y AU - Tomino Y FAU - Miura, M AU - Miura M FAU - Suga, T AU - Suga T FAU - Endoh, M AU - Endoh M FAU - Nomoto, Y AU - Nomoto Y FAU - Sakai, H AU - Sakai H LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Japan TA - Tokai J Exp Clin Med JT - The Tokai journal of experimental and clinical medicine JID - 7704186 RN - 64ALC7F90C (Dipyridamole) RN - 70G54NQL71 (Adrenochrome) RN - 81F061RQS4 (carbazochrome) SB - IM MH - Adrenochrome/analogs & derivatives/therapeutic use MH - Dipyridamole/*therapeutic use MH - Glomerulonephritis/drug therapy MH - Glomerulonephritis, IGA/*drug therapy MH - Hematuria/drug therapy MH - Humans MH - Proteinuria/drug therapy EDAT- 1986/11/01 00:00 MHDA- 1986/11/01 00:01 CRDT- 1986/11/01 00:00 PHST- 1986/11/01 00:00 [pubmed] PHST- 1986/11/01 00:01 [medline] PHST- 1986/11/01 00:00 [entrez] PST - ppublish SO - Tokai J Exp Clin Med. 1986 Nov;11(5):329-33.