PMID- 29604306
OWN - NLM
STAT- MEDLINE
DCOM- 20190530
LR  - 20190530
IS  - 1872-7697 (Electronic)
IS  - 0167-8760 (Linking)
VI  - 128
DP  - 2018 Jun
TI  - Exploring the maximum duration of the contingent negative variation.
PG  - 52-61
LID - S0167-8760(17)30550-0 [pii]
LID - 10.1016/j.ijpsycho.2018.03.020 [doi]
AB  - While the contingent negative variation (CNV) has been the subject of extensive 
      research over the last fifty years, the maximum duration during which such 
      cortical negativity can be maintained has, to the best of our knowledge, never 
      been systematically explored. Participants were presented with the classic S1-S2 
      paradigm task, where a warning stimulus (S1) acts as a cue for the appearance of 
      an imperative stimulus (S2). A fast motor response was required upon S2 arrival. 
      Inter-stimulus intervals (ISIs) of 2.5, 5, 7.5 and 10 s duration were presented 
      in blocked fashion. Data was analysed using both EEG referenced to linked 
      mastoids and the current source density (CSD) technique, which maximizes the 
      cortical origin of the measured voltage. Mean late CNV (lCNV) amplitude was found 
      to be significantly higher for fast reaction time (RT) trials when CSD data was 
      split according to the median into 'fast' and 'slow' RT halves. Post-hoc 
      comparisons showed that this RT effect was particularly strong for the 10 s 
      condition. This may be explained by the lack of an lCNV component and thus of 
      cortical negativity prior to S2 in the 10 s condition. Our results suggest that 
      intervals of a duration between 7.5 and 10 s represent the upper boundary during 
      which the lCNV component can be elicited.
CI  - Copyright (c) 2018 Elsevier B.V. All rights reserved.
FAU - Rohricht, Jonas
AU  - Rohricht J
AD  - Department of Psychosomatic Medicine and Psychotherapy, Medical Faculty, Medical 
      Center - University of Freiburg, Freiburg, Germany.
FAU - Jo, Han-Gue
AU  - Jo HG
AD  - Department of Psychiatry, Psychotherapy and Psychosomatics, Medical Faculty, RWTH 
      Aachen University, Aachen, Germany. Electronic address: hjo@ukaachen.de.
FAU - Wittmann, Marc
AU  - Wittmann M
AD  - Institute for Frontier Areas of Psychology and Mental Health, Freiburg, Germany.
FAU - Schmidt, Stefan
AU  - Schmidt S
AD  - Department of Psychosomatic Medicine and Psychotherapy, Medical Faculty, Medical 
      Center - University of Freiburg, Freiburg, Germany; Institute for Transcultural 
      Health Studies, European University Viadrina, Frankfurt (Oder), Germany.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180328
PL  - Netherlands
TA  - Int J Psychophysiol
JT  - International journal of psychophysiology : official journal of the International 
      Organization of Psychophysiology
JID - 8406214
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Cerebral Cortex/*physiology
MH  - Contingent Negative Variation/*physiology
MH  - Electroencephalography/*methods
MH  - Female
MH  - Humans
MH  - Male
MH  - Psychomotor Performance/*physiology
MH  - Reaction Time/*physiology
MH  - Time Factors
MH  - Young Adult
OTO - NOTNLM
OT  - Contingent negative variation
OT  - Current source density
OT  - Event-related potential
OT  - Reaction time
OT  - Slow cortical potential
EDAT- 2018/04/01 06:00
MHDA- 2019/05/31 06:00
CRDT- 2018/04/01 06:00
PHST- 2017/09/26 00:00 [received]
PHST- 2018/03/15 00:00 [revised]
PHST- 2018/03/22 00:00 [accepted]
PHST- 2018/04/01 06:00 [pubmed]
PHST- 2019/05/31 06:00 [medline]
PHST- 2018/04/01 06:00 [entrez]
AID - S0167-8760(17)30550-0 [pii]
AID - 10.1016/j.ijpsycho.2018.03.020 [doi]
PST - ppublish
SO  - Int J Psychophysiol. 2018 Jun;128:52-61. doi: 10.1016/j.ijpsycho.2018.03.020. 
      Epub 2018 Mar 28.