PMID- 29611659
OWN - NLM
STAT- MEDLINE
DCOM- 20190802
LR  - 20190802
IS  - 1505-1773 (Print)
IS  - 1505-1773 (Linking)
VI  - 20
IP  - 4
DP  - 2017 Dec
TI  - Comparison of serum concentrations of environmental allergen-specific IgE in 
      atopic and healthy (nonatopic) horses.
PG  - 789-794
LID - 10.1515/pjvs-2017-0099 [doi]
AB  - Allergic responses in humans, horses and other species are mediated by 
      immunoglobulin E (IgE) antibodies. Serum testing to detect allergen-specific IgE 
      antibodies has been developed for dogs, cats and horses; this allows for the 
      identification of allergens and determination of appropriate allergen- specific 
      immunotherapies. This study compared serum allergen-specific IgE concentrations 
      in atopic and healthy horses. The study was performed on Malopolski breed atopic 
      (n=21) and nonatopic (n=21) clinically healthy horses. Allergen-specific IgE 
      serum concentrations were measured in summer seasons of 2008-2015 using a 
      monoclonal anti-IgE antibody. A Northern and Central European allergen panel 
      containing mite, insect, mould and plant pollen allergens, including 15 tests of 
      individual allergens and 5 tests of allergen mixtures was used. The mean 
      allergen-specific IgE concentrations in the atopic and normal horse populations 
      were compared. Among the atopic horses, the strongest positive reactions occurred 
      against the storage mites Tyrophagus putrescentiae and the domestic mite 
      Dermatophagoides farinae. The atopic horses also demonstrated high IgE 
      concentrations against insects, particularly Tabanus sp., the plant pollens 
      colza, cultivated rye and the mould pollen mixture Aspergillus/Penicillium. No 
      horses in the atopic group were IgE-negative. Among all mite, insect, mould and 
      some plant allergen groups the differences in mean specific IgE concentrations 
      between allergic and healthy horses were significant. The mean IgE concentrations 
      for most allergen groups were significantly higher in the atopic horses than in 
      the healthy animals. However, a high incidence of positive reactions was observed 
      in both healthy and allergic horses. Our results showed a high frequency of 
      polysensitization in atopic horses.
CI  - Copyright(c) by the Polish Academy of Sciences.
FAU - Wilkolek, P
AU  - Wilkolek P
AD  - Sub-Department of Clinical Diagnostics and Veterinary Dermatology, Faculty of 
      Veterinary Medicine, University of Life Sciences in Lublin, Gleboka 30, 20-612 
      Lublin, Poland.
FAU - Sitkowski, W
AU  - Sitkowski W
AD  - Sub-Department of Clinical Diagnostics and Veterinary Dermatology, Faculty of 
      Veterinary Medicine, University of Life Sciences in Lublin, Gleboka 30, 20-612 
      Lublin, Poland.
FAU - Szczepanik, M
AU  - Szczepanik M
AD  - Sub-Department of Clinical Diagnostics and Veterinary Dermatology, Faculty of 
      Veterinary Medicine, University of Life Sciences in Lublin, Gleboka 30, 20-612 
      Lublin, Poland.
FAU - Adamek, L
AU  - Adamek L
AD  - Sub-Department of Clinical Diagnostics and Veterinary Dermatology, Faculty of 
      Veterinary Medicine, University of Life Sciences in Lublin, Gleboka 30, 20-612 
      Lublin, Poland.
FAU - Pluta, M
AU  - Pluta M
AD  - Equine Breeding and Management Unit, Department of Biology and Animal Breeding, 
      University of Life Sciences in Lublin, Akademicka St. 13, 20-950 Lublin, Poland.
FAU - Taszkun, I
AU  - Taszkun I
AD  - Sub-Department of Clinical Diagnostics and Veterinary Dermatology, Faculty of 
      Veterinary Medicine, University of Life Sciences in Lublin, Gleboka 30, 20-612 
      Lublin, Poland.
FAU - Golynski, M
AU  - Golynski M
AD  - Department of Internal Diseases, Faculty of Veterinary Medicine, University of 
      Life Sciences in Lublin, Gleboka 30, 20-612 Lublin, Poland.
FAU - Malinowska, A
AU  - Malinowska A
AD  - Sub-Department of Clinical Diagnostics and Veterinary Dermatology, Faculty of 
      Veterinary Medicine, University of Life Sciences in Lublin, Gleboka 30, 20-612 
      Lublin, Poland.
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Pol J Vet Sci
JT  - Polish journal of veterinary sciences
JID - 101125473
RN  - 0 (Allergens)
RN  - 37341-29-0 (Immunoglobulin E)
MH  - Allergens/*immunology
MH  - Animals
MH  - Antibody Specificity/physiology
MH  - Dermatitis, Atopic/blood/*veterinary
MH  - Fungi/immunology
MH  - Horse Diseases/*blood/immunology
MH  - Horses
MH  - Immunoglobulin E/*blood
MH  - Mites/immunology
MH  - Pollen/immunology
OTO - NOTNLM
OT  - IgE
OT  - allergens
OT  - equine atopic dermatitis
OT  - healthy horses
OT  - immunology
EDAT- 2018/04/04 06:00
MHDA- 2019/08/03 06:00
CRDT- 2018/04/04 06:00
PHST- 2018/04/04 06:00 [entrez]
PHST- 2018/04/04 06:00 [pubmed]
PHST- 2019/08/03 06:00 [medline]
AID - 10.1515/pjvs-2017-0099 [doi]
PST - ppublish
SO  - Pol J Vet Sci. 2017 Dec;20(4):789-794. doi: 10.1515/pjvs-2017-0099.