PMID- 29613987 OWN - NLM STAT- MEDLINE DCOM- 20180806 LR - 20180806 IS - 1532-3145 (Electronic) IS - 0363-8715 (Linking) VI - 42 IP - 4 DP - 2018 Jul/Aug TI - Focal Myocardial Damage in Cardiac Sarcoidosis Characterized by Strain Analysis on Magnetic Resonance Tagged Imaging in Comparison with Fluorodeoxyglucose Positron Emission Tomography Accumulation and Magnetic Resonance Late Gadolinium Enhancement. PG - 607-613 LID - 10.1097/RCT.0000000000000733 [doi] AB - OBJECTIVE: The aims of this study were to characterize focal myocardial damage of cardiac sarcoidosis by strain analysis and to compare it with late gadolinium enhancement (LGE) and fluorodeoxyglucose (FDG) positron emission tomography. METHODS: We reviewed 208 segments from 13 cardiac sarcoidosis patients and measured the circumferential strain (Ecc) and the strain change per second (Ecc rate). The mean Ecc and Ecc rate values were compared between the FDG(+) and FDG(-), and the LGE(+) and LGE(-) segments using Welch's t test. RESULTS: The peak and max Ecc rates were better in the LGE(-) segments than in the LGE(+) segments (-11.8 vs -8.9%, 40.5 vs 29.7%/s, both P < 0.001). The max Ecc rate was higher in the FDG(-) segments than in the FDG(+) segments (39.2 vs 31.7%/s, P < 0.001), but the peak Ecc did not differ between the FDG(+) and FDG(-) segments (-11.2 vs -10.1%, P = 0.17). CONCLUSIONS: Strain analysis could reveal focal myocardial damage in the FDG(+) or the LGE(+) segments. FAU - Watanabe, Yoshiaki AU - Watanabe Y AD - From the Department of Radiology, and. FAU - Nishii, Tatsuya AU - Nishii T AD - From the Department of Radiology, and. FAU - Shimoyama, Shinsuke AU - Shimoyama S AD - From the Department of Radiology, and. FAU - Ito, Tatsuro AU - Ito T AD - Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan. FAU - Mori, Shumpei AU - Mori S AD - Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan. FAU - Kono, Atsushi K AU - Kono AK AD - From the Department of Radiology, and. FAU - Takahashi, Satoru AU - Takahashi S AD - From the Department of Radiology, and. FAU - Hirata, Ken-Ichi AU - Hirata KI AD - Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan. FAU - Sugimura, Kazuro AU - Sugimura K AD - From the Department of Radiology, and. LA - eng PT - Comparative Study PT - Journal Article PL - United States TA - J Comput Assist Tomogr JT - Journal of computer assisted tomography JID - 7703942 RN - 0 (Contrast Media) RN - 0 (Radiopharmaceuticals) RN - 0Z5B2CJX4D (Fluorodeoxyglucose F18) RN - K2I13DR72L (Gadolinium DTPA) SB - IM MH - Aged MH - Contrast Media MH - Female MH - *Fluorodeoxyglucose F18 MH - *Gadolinium DTPA MH - Heart/diagnostic imaging MH - Humans MH - Image Enhancement/*methods MH - Magnetic Resonance Imaging/*methods MH - Magnetic Resonance Imaging, Cine MH - Male MH - Middle Aged MH - Myocardium/pathology MH - Positron-Emission Tomography/*methods MH - Radiopharmaceuticals MH - Reproducibility of Results MH - Retrospective Studies MH - Sarcoidosis/diagnostic imaging/*pathology EDAT- 2018/04/04 06:00 MHDA- 2018/08/07 06:00 CRDT- 2018/04/04 06:00 PHST- 2018/04/04 06:00 [pubmed] PHST- 2018/08/07 06:00 [medline] PHST- 2018/04/04 06:00 [entrez] AID - 10.1097/RCT.0000000000000733 [doi] PST - ppublish SO - J Comput Assist Tomogr. 2018 Jul/Aug;42(4):607-613. doi: 10.1097/RCT.0000000000000733.