PMID- 29614413
OWN - NLM
STAT- MEDLINE
DCOM- 20180814
LR  - 20181202
IS  - 1879-1298 (Electronic)
IS  - 0045-6535 (Linking)
VI  - 203
DP  - 2018 Jul
TI  - Differential behaviors of silver nanoparticles and silver ions towards cysteine: 
      Bioremediation and toxicity to Phanerochaete chrysosporium.
PG  - 199-208
LID - S0045-6535(18)30561-7 [pii]
LID - 10.1016/j.chemosphere.2018.03.144 [doi]
AB  - Potential transformations of silver nanoparticles (AgNPs) upon interaction with 
      naturally ubiquitous organic ligands in aquatic environments influence their 
      transport, persistence, bioavailability, and subsequent toxicity to organisms. In 
      this study, differential behaviors of AgNPs and silver ions (Ag(+)) towards 
      cysteine (Cys), an amino acid representative of thiol ligands that easily 
      coordinate to Ag(+) and graft to nanoparticle surfaces, were investigated in the 
      aspects of bioremediation and their toxicity to Phanerochaete chrysosporium. 
      Total Ag removal, 2,4-dichlorophenol (2,4-DCP) degradation, extracellular protein 
      secretion, and cellular viability were enhanced to some extent after supplement 
      of various concentrations of cysteine under stress of AgNPs and Ag(+). However, 
      an obvious decrease in total Ag uptake was observed after 5-50 muM cysteine 
      addition in the groups treated with 10 muM AgNPs and 1 muM Ag(+), especially at a 
      Cys:Ag molar ratio of 5. More stabilization in uptake pattern at this ratio was 
      detected under Ag(+) exposure than that under AgNP exposure. Furthermore, in the 
      absence of cysteine, all Ag(+) treatments stimulated the generation of reactive 
      oxygen species (ROS) more significantly than high-dose AgNPs did. However, 
      cysteine supply under AgNP/Ag(+) stress aggravated ROS levels, albeit alleviated 
      at 100 muM Ag(+), indicating that the toxicity profiles of AgNPs and Ag(+) to 
      P. chrysosporium could be exacerbated or marginally mitigated by cysteine. The 
      results obtained were possibly associated with the lability and bioavailability 
      of AgNP/Ag(+)-cysteine complexes.
CI  - Copyright (c) 2018 Elsevier Ltd. All rights reserved.
FAU - Huang, Zhenzhen
AU  - Huang Z
AD  - College of Environmental Science and Engineering, Hunan University and Key 
      Laboratory of Environmental Biology and Pollution Control (Hunan University), 
      Ministry of Education, Changsha, 410082, PR China.
FAU - Zeng, Zhuotong
AU  - Zeng Z
AD  - Department of Dermatology, Second Xiangya Hospital, Central South University, 
      Changsha, 410011, PR China.
FAU - Chen, Anwei
AU  - Chen A
AD  - College of Resources and Environment, Hunan Agricultural University, Changsha, 
      410128, PR China.
FAU - Zeng, Guangming
AU  - Zeng G
AD  - College of Environmental Science and Engineering, Hunan University and Key 
      Laboratory of Environmental Biology and Pollution Control (Hunan University), 
      Ministry of Education, Changsha, 410082, PR China. Electronic address: 
      zgming@hnu.edu.cn.
FAU - Xiao, Rong
AU  - Xiao R
AD  - Department of Dermatology, Second Xiangya Hospital, Central South University, 
      Changsha, 410011, PR China. Electronic address: xiaorong65@csu.edu.cn.
FAU - Xu, Piao
AU  - Xu P
AD  - College of Environmental Science and Engineering, Hunan University and Key 
      Laboratory of Environmental Biology and Pollution Control (Hunan University), 
      Ministry of Education, Changsha, 410082, PR China.
FAU - He, Kai
AU  - He K
AD  - College of Environmental Science and Engineering, Hunan University and Key 
      Laboratory of Environmental Biology and Pollution Control (Hunan University), 
      Ministry of Education, Changsha, 410082, PR China.
FAU - Song, Zhongxian
AU  - Song Z
AD  - School of Municipal and Environmental Engineering, Henan University of Urban 
      Construction, Pingdingshan, 467036, PR China.
FAU - Hu, Liang
AU  - Hu L
AD  - College of Environmental Science and Engineering, Hunan University and Key 
      Laboratory of Environmental Biology and Pollution Control (Hunan University), 
      Ministry of Education, Changsha, 410082, PR China.
FAU - Peng, Min
AU  - Peng M
AD  - College of Environmental Science and Engineering, Hunan University and Key 
      Laboratory of Environmental Biology and Pollution Control (Hunan University), 
      Ministry of Education, Changsha, 410082, PR China.
FAU - Huang, Tiantian
AU  - Huang T
AD  - College of Environmental Science and Engineering, Hunan University and Key 
      Laboratory of Environmental Biology and Pollution Control (Hunan University), 
      Ministry of Education, Changsha, 410082, PR China.
FAU - Chen, Guiqiu
AU  - Chen G
AD  - College of Environmental Science and Engineering, Hunan University and Key 
      Laboratory of Environmental Biology and Pollution Control (Hunan University), 
      Ministry of Education, Changsha, 410082, PR China.
LA  - eng
PT  - Journal Article
DEP - 20180321
PL  - England
TA  - Chemosphere
JT  - Chemosphere
JID - 0320657
RN  - 0 (Reactive Oxygen Species)
RN  - 3M4G523W1G (Silver)
RN  - K848JZ4886 (Cysteine)
SB  - IM
MH  - Biodegradation, Environmental
MH  - Cysteine/*chemistry/metabolism
MH  - Metal Nanoparticles/chemistry/toxicity
MH  - Phanerochaete/*drug effects/metabolism
MH  - Reactive Oxygen Species/metabolism
MH  - Silver/*chemistry/toxicity
MH  - Water Purification/*methods
OTO - NOTNLM
OT  - Bioremediation
OT  - Cysteine
OT  - Phanerochaete chrysosporium
OT  - Silver ion
OT  - Silver nanoparticles
OT  - Toxicity
EDAT- 2018/04/04 06:00
MHDA- 2018/08/15 06:00
CRDT- 2018/04/04 06:00
PHST- 2018/01/31 00:00 [received]
PHST- 2018/03/18 00:00 [revised]
PHST- 2018/03/21 00:00 [accepted]
PHST- 2018/04/04 06:00 [pubmed]
PHST- 2018/08/15 06:00 [medline]
PHST- 2018/04/04 06:00 [entrez]
AID - S0045-6535(18)30561-7 [pii]
AID - 10.1016/j.chemosphere.2018.03.144 [doi]
PST - ppublish
SO  - Chemosphere. 2018 Jul;203:199-208. doi: 10.1016/j.chemosphere.2018.03.144. Epub 
      2018 Mar 21.