PMID- 29617423
OWN - NLM
STAT- MEDLINE
DCOM- 20180730
LR  - 20181114
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 13
IP  - 4
DP  - 2018
TI  - HIV prevalence by ethnic group covaries with prevalence of herpes simplex virus-2 
      and high-risk sex in Uganda: An ecological study.
PG  - e0195431
LID - 10.1371/journal.pone.0195431 [doi]
LID - e0195431
AB  - BACKGROUND: HIV prevalence varies from 1.7% to 14.8% between ethnic groups in 
      Uganda. Understanding the factors responsible for this heterogeneity in HIV 
      spread may guide prevention efforts. METHODS: We evaluated the relationship 
      between HIV prevalence by ethnic group and a range of risk factors as well as the 
      prevalence of herpes simplex virus-2 (HSV-2), syphilis and symptomatic STIs in 
      the 2004/2005 Uganda HIV/AIDS Sero-Behavioural Survey-a two stage, nationally 
      representative, population based survey of 15-59-year-olds. Spearman's 
      correlation was used to assess the relationship between HIV prevalence and each 
      variable. RESULTS: There was a positive association between HIV prevalence and 
      HSV-2, symptomatic STIs and high-risk sex (sex with a non-cohabiting, non-marital 
      partner) for women. Non-significant positive associations were present between 
      HIV and high-risk sex for men and lifetime number of partners for men and women. 
      CONCLUSION: Variation in sexual behavior may contribute to the variations in HIV, 
      HSV-2 and other STI prevalence by ethnic group in Uganda. Further work is 
      necessary to delineate which combinations of risk factors determine differential 
      STI spread in Uganda.
FAU - Kenyon, Chris R
AU  - Kenyon CR
AUID- ORCID: 0000-0002-2557-8998
AD  - HIV/STI Unit, Institute of Tropical Medicine, Antwerp, Belgium.
AD  - Division of Infectious Diseases and HIV Medicine, University of Cape Town, Cape 
      Town, South Africa.
LA  - eng
PT  - Journal Article
DEP - 20180404
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Circumcision, Male/ethnology
MH  - Female
MH  - HIV Infections/*ethnology
MH  - Herpes Simplex/*ethnology
MH  - *Herpesvirus 2, Human
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prevalence
MH  - Risk Factors
MH  - Sex Factors
MH  - Syphilis/ethnology
MH  - Uganda/epidemiology
MH  - Unsafe Sex/*ethnology
MH  - Young Adult
PMC - PMC5884562
COIS- Competing Interests: The authors have declared that no competing interests exist.
EDAT- 2018/04/05 06:00
MHDA- 2018/07/31 06:00
PMCR- 2018/04/04
CRDT- 2018/04/05 06:00
PHST- 2017/05/24 00:00 [received]
PHST- 2018/03/22 00:00 [accepted]
PHST- 2018/04/05 06:00 [entrez]
PHST- 2018/04/05 06:00 [pubmed]
PHST- 2018/07/31 06:00 [medline]
PHST- 2018/04/04 00:00 [pmc-release]
AID - PONE-D-17-19933 [pii]
AID - 10.1371/journal.pone.0195431 [doi]
PST - epublish
SO  - PLoS One. 2018 Apr 4;13(4):e0195431. doi: 10.1371/journal.pone.0195431. 
      eCollection 2018.