PMID- 29618683
OWN - NLM
STAT- MEDLINE
DCOM- 20190702
LR  - 20190702
IS  - 0485-1439 (Print)
IS  - 0485-1439 (Linking)
VI  - 59
IP  - 3
DP  - 2018
TI  - [MALT lymphoma with t (X;14) (p11.2;q32) developing during the course of 
      cutaneous leukocytoclastic angitis].
PG  - 269-274
LID - 10.11406/rinketsu.59.269 [doi]
AB  - A 73-year-old man with left parotid gland swelling over 2 months was referred to 
      our hospital in March 201X. Purpura on the lower legs had been recurrent for >20 
      years. Biopsy of the parotid gland demonstrated diffuse infiltration of abnormal 
      lymphocytes that were negative for CD10 and positive for CD19, CD20, and kappa-chain. 
      The Ki-67 positivity was <10%; lymphoepithelial lesions were observed. The 
      patient was diagnosed with extranodal marginal zone lymphoma of mucosa-associated 
      lymphoid tissue (MALT lymphoma). Chromosome analysis revealed t (X;14) 
      (p11.2;q32), and fluorescence in situ hybridization (FISH) of metaphase spreads 
      showed three signals of the immunoglobulin heavy chain (IGH) gene on the 
      derivative chromosomes X and 14, besides the normal chromosome 14. CT findings of 
      parotid glands were suggestive of Sjogren syndrome, and biopsy of the purpura on 
      the leg demonstrated leukocytoclastic vasculitis. In the literature, only seven 
      patients with lymphoma and t (X;14) translocation have been reported. Of these, 
      five patients had MALT lymphoma, one had nodal marginal zone lymphoma, and one 
      had diffuse large B-cell lymphoma. In all patients, lymphoma evolved from 
      previous autoimmune diseases. It is suggested that MALT lymphoma with the t 
      (X;14) translocation forms a new entity of lymphoma.
FAU - Uemura, Yu
AU  - Uemura Y
AD  - Department of Internal Medicine, Division of Hematology and Oncology, St. 
      Marianna University School of Medicine.
FAU - Sakai, Hirotaka
AU  - Sakai H
AD  - Department of Internal Medicine, Division of Hematology and Oncology, St. 
      Marianna University School of Medicine.
FAU - Saiki, Yusuke
AU  - Saiki Y
AD  - Department of Internal Medicine, Division of Hematology and Oncology, St. 
      Marianna University School of Medicine.
FAU - Uchida, Akiko
AU  - Uchida A
AD  - Department of Internal Medicine, Division of Hematology and Oncology, St. 
      Marianna University School of Medicine.
FAU - Sato, Kazuyuki
AU  - Sato K
AD  - Department of Internal Medicine, Division of Hematology and Oncology, St. 
      Marianna University School of Medicine.
FAU - Tsuruoka, Yuka
AU  - Tsuruoka Y
AD  - Department of Internal Medicine, Division of Hematology and Oncology, St. 
      Marianna University School of Medicine.
FAU - Yokoi, Satoshi
AU  - Yokoi S
AD  - Department of Internal Medicine, Division of Hematology and Oncology, St. 
      Marianna University School of Medicine.
FAU - Nishio, Yuji
AU  - Nishio Y
AD  - Department of Internal Medicine, Division of Hematology and Oncology, St. 
      Marianna University School of Medicine.
FAU - Matsunawa, Manabu
AU  - Matsunawa M
AD  - Department of Internal Medicine, Division of Hematology and Oncology, St. 
      Marianna University School of Medicine.
FAU - Suzuki, Yoshinori
AU  - Suzuki Y
AD  - Department of Internal Medicine, Division of Hematology and Oncology, St. 
      Marianna University School of Medicine.
FAU - Isobe, Yasushi
AU  - Isobe Y
AD  - Department of Internal Medicine, Division of Hematology and Oncology, St. 
      Marianna University School of Medicine.
FAU - Kato, Masayuki
AU  - Kato M
AD  - Department of Internal Medicine, Division of Hematology and Oncology, St. 
      Marianna University School of Medicine.
FAU - Tomita, Naoto
AU  - Tomita N
AD  - Department of Internal Medicine, Division of Hematology and Oncology, St. 
      Marianna University School of Medicine.
FAU - Inoue, Yasuyuki
AU  - Inoue Y
AD  - Department of Internal Medicine, Division of Hematology and Oncology, St. 
      Marianna University School of Medicine.
FAU - Miura, Ikuo
AU  - Miura I
AD  - Department of Internal Medicine, Division of Hematology and Oncology, St. 
      Marianna University School of Medicine.
LA  - jpn
PT  - Case Reports
PT  - Journal Article
PL  - Japan
TA  - Rinsho Ketsueki
JT  - [Rinsho ketsueki] The Japanese journal of clinical hematology
JID - 2984782R
SB  - IM
MH  - Aged
MH  - Chromosomes, Human, Pair 14/genetics
MH  - Chromosomes, Human, X/genetics
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Lymphoma, B-Cell, Marginal Zone/*diagnosis/genetics
MH  - Male
MH  - Translocation, Genetic
MH  - Vasculitis, Leukocytoclastic, Cutaneous/*pathology
OTO - NOTNLM
OT  - Autoimmune disease
OT  - MALT lymphoma
OT  - Parotid gland
OT  - Xp11.2
EDAT- 2018/04/06 06:00
MHDA- 2019/07/03 06:00
CRDT- 2018/04/06 06:00
PHST- 2018/04/06 06:00 [entrez]
PHST- 2018/04/06 06:00 [pubmed]
PHST- 2019/07/03 06:00 [medline]
AID - 10.11406/rinketsu.59.269 [doi]
PST - ppublish
SO  - Rinsho Ketsueki. 2018;59(3):269-274. doi: 10.11406/rinketsu.59.269.