PMID- 2961927
OWN - NLM
STAT- MEDLINE
DCOM- 19880211
LR  - 20170214
IS  - 0023-6772 (Print)
IS  - 0023-6772 (Linking)
VI  - 21
IP  - 4
DP  - 1987 Oct
TI  - Quantitative studies of lymphoid organs, blood and lymph in inbred athymic and 
      euthymic LEW rats under germfree and specified-pathogen-free conditions.
PG  - 342-7
AB  - Four groups of inbred male LEW rats were examined: A, germfree athymic; B, 
      specified pathogen free (SPF) athymic; C, germfree euthymic; D, SPF euthymic. All 
      animals were killed at 18 weeks and compared with respect to body weight, 
      histological appearance and cell density of the lymphoid organs, haematological 
      values and differential counts of bone marrow, peripheral blood and lymph. 
      Athymic rats had a lower body weight, less densely populated lymphoid organs, and 
      fewer lymphocytes in the blood and lymph compared with euthymic animals. No 
      difference was seen between athymic rats under germfree and SPF conditions, and 
      in general the differences between athymic and euthymic animals were less 
      pronounced under germfree conditions.
FAU - Klausen, B
AU  - Klausen B
AD  - Department of Oral Diagnosis, Royal Dental College, Copenhagen, Denmark.
FAU - Hougen, H P
AU  - Hougen HP
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Lab Anim
JT  - Laboratory animals
JID - 0112725
SB  - IM
MH  - Animals
MH  - Body Weight
MH  - *Bone Marrow Cells
MH  - *Germ-Free Life
MH  - Leukocyte Count
MH  - Lymph/*cytology
MH  - Lymph Nodes/anatomy & histology/cytology
MH  - Lymphocytes
MH  - Lymphoid Tissue/*anatomy & histology/cytology
MH  - Male
MH  - Organ Size
MH  - Rats
MH  - Rats, Inbred Lew/*anatomy & histology/blood
MH  - Rats, Inbred Strains/*anatomy & histology
MH  - Rats, Mutant Strains/*anatomy & histology
MH  - Rats, Nude/*anatomy & histology/blood
MH  - Specific Pathogen-Free Organisms
MH  - Spleen/anatomy & histology/cytology
MH  - Thymus Gland/anatomy & histology/cytology
EDAT- 1987/10/01 00:00
MHDA- 1987/10/01 00:01
CRDT- 1987/10/01 00:00
PHST- 1987/10/01 00:00 [pubmed]
PHST- 1987/10/01 00:01 [medline]
PHST- 1987/10/01 00:00 [entrez]
AID - 10.1258/002367787781363318 [doi]
PST - ppublish
SO  - Lab Anim. 1987 Oct;21(4):342-7. doi: 10.1258/002367787781363318.