PMID- 29619511
OWN - NLM
STAT- MEDLINE
DCOM- 20181224
LR  - 20181224
IS  - 1432-2323 (Electronic)
IS  - 0364-2313 (Print)
IS  - 0364-2313 (Linking)
VI  - 42
IP  - 10
DP  - 2018 Oct
TI  - Results of Magnetic Sphincter Augmentation for Gastroesophageal Reflux Disease.
PG  - 3263-3269
LID - 10.1007/s00268-018-4608-8 [doi]
AB  - BACKGROUND: Magnetic sphincter augmentation (MSA) is a modern treatment option 
      for gastroesophageal reflux disease (GERD); however, laparoscopic fundoplication 
      remains the gold standard. The aim of the study was to evaluate outcomes of MSA 
      patients at a reflux center. METHODS: A retrospective review was performed of all 
      patients that underwent MSA between March 2012 and November 2017. Out of 110 
      patients, 68 with a follow-up >3 months were included. Postoperative 
      gastrointestinal symptoms, proton pump inhibitor (PPI) intake, 
      GERD-Health-related Quality of Life (GERD-HRQL) and alimentary satisfaction (AS) 
      were assessed. Postoperative esophageal functioning tests were performed in 50% 
      of patients. RESULTS: Sixty-eight patients underwent MSA; hiatal repair was 
      performed in 31 cases. The median OR time was 27 min, and no intraoperative 
      complications occurred. The median follow-up was 13 months (IQR 4.2-45). 
      Endoscopic dilatation was performed in 2 patients (3%) and device removal in 
      another 2 cases. The postoperative GERD-HRQL score was significantly reduced (3 
      vs. 24; p < 0.001) and the median AS was 8/10. Preoperative experienced 
      heartburn, regurgitations and dysphagia were eliminated in 92, 96 and 100%. 
      Postoperative new-onset difficulties swallowing with solids only were reported to 
      occur occasionally by 16% and rarely by 21% of patients. Satisfaction with 
      heartburn relief was 95%, and the overall outcome was rated excellent/good in 
      89%. PPI dependency was eliminated in 87%. The median total percentage pH < 4 and 
      number of reflux episodes were significantly reduced. Postoperative pH results 
      were negative or slightly above the norm in 79% and 12%, respectively. 
      CONCLUSION: Sphincter augmentation results in significantly reduced reflux 
      symptoms, increased GERD-specific Quality of Life and excellent alimentary 
      satisfaction with low perioperative morbidity. This procedure should be 
      considered an excellent alternative to fundoplication in the treatment of GERD.
FAU - Schwameis, Katrin
AU  - Schwameis K
AD  - Department of Surgery, Division of General Surgery, Medical University of Vienna, 
      Waehringer Guertel 18-20, Vienna, 1090, Austria.
FAU - Nikolic, Milena
AU  - Nikolic M
AD  - Department of Surgery, Division of General Surgery, Medical University of Vienna, 
      Waehringer Guertel 18-20, Vienna, 1090, Austria.
FAU - Morales Castellano, Deivis G
AU  - Morales Castellano DG
AD  - Department of Surgery, Division of General Surgery, Medical University of Vienna, 
      Waehringer Guertel 18-20, Vienna, 1090, Austria.
FAU - Steindl, Ariane
AU  - Steindl A
AD  - Department of Surgery, Division of General Surgery, Medical University of Vienna, 
      Waehringer Guertel 18-20, Vienna, 1090, Austria.
FAU - Macheck, Sarah
AU  - Macheck S
AD  - Department of Surgery, Division of General Surgery, Medical University of Vienna, 
      Waehringer Guertel 18-20, Vienna, 1090, Austria.
FAU - Kristo, Ivan
AU  - Kristo I
AD  - Department of Surgery, Division of General Surgery, Medical University of Vienna, 
      Waehringer Guertel 18-20, Vienna, 1090, Austria.
FAU - Zorner, Barbara
AU  - Zorner B
AD  - Department of Surgery, Division of General Surgery, Medical University of Vienna, 
      Waehringer Guertel 18-20, Vienna, 1090, Austria.
FAU - Schoppmann, Sebastian F
AU  - Schoppmann SF
AD  - Department of Surgery, Division of General Surgery, Medical University of Vienna, 
      Waehringer Guertel 18-20, Vienna, 1090, Austria. 
      sebastian.schoppmann@meduniwien.ac.at.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - World J Surg
JT  - World journal of surgery
JID - 7704052
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Adult
MH  - Esophageal Sphincter, Lower/*surgery
MH  - Female
MH  - Gastroesophageal Reflux/drug therapy/*surgery
MH  - Humans
MH  - Laparoscopy
MH  - Male
MH  - Middle Aged
MH  - Prosthesis Implantation/*instrumentation/methods
MH  - Proton Pump Inhibitors/therapeutic use
MH  - Retrospective Studies
MH  - Treatment Outcome
PMC - PMC6132868
COIS- All authors declare that they have no conflict of interest.
EDAT- 2018/04/06 06:00
MHDA- 2018/12/26 06:00
PMCR- 2018/04/04
CRDT- 2018/04/06 06:00
PHST- 2018/04/06 06:00 [pubmed]
PHST- 2018/12/26 06:00 [medline]
PHST- 2018/04/06 06:00 [entrez]
PHST- 2018/04/04 00:00 [pmc-release]
AID - 10.1007/s00268-018-4608-8 [pii]
AID - 4608 [pii]
AID - 10.1007/s00268-018-4608-8 [doi]
PST - ppublish
SO  - World J Surg. 2018 Oct;42(10):3263-3269. doi: 10.1007/s00268-018-4608-8.