PMID- 29621507 OWN - NLM STAT- MEDLINE DCOM- 20190627 LR - 20190627 IS - 1879-1891 (Electronic) IS - 0002-9394 (Linking) VI - 191 DP - 2018 Jul TI - Internal Limiting Membrane Peeling in Macula-off Retinal Detachment Complicated by Grade B Proliferative Vitreoretinopathy. PG - 1-6 LID - S0002-9394(18)30152-1 [pii] LID - 10.1016/j.ajo.2018.03.037 [doi] AB - PURPOSE: To investigate the clinical benefit of internal limiting membrane (ILM) peeling as a surgical adjunct in the repair of primary retinal detachment (RD) complicated by grade B proliferative vitreoretinopathy (PVR). DESIGN: Retrospective, interventional, comparative case series. METHODS: Setting, study population, observationalprocedures and Main outcome measures. SETTING: Institutional. STUDY POPULATION: Seventy-five consecutive patients who underwent vitrectomy for primary macula-off RD complicated by grade B PVR. OBSERVATIONAL PROCEDURES: Patients were divided into an ILM peeling (Group P) and a no ILM peeling group (Group NP). MAIN OUTCOME MEASURES: Anatomic success rate, best-corrected visual acuity, and spectral-domain optical coherence tomography (SD-OCT) characteristics were collected at 1 and 6 months. RESULTS: In all, 37 eyes with ILM peeling were included in Group P and 38 eyes without ILM peeling were included in Group NP. The anatomic success rate after single surgery was higher in Group P (89%) than in Group NP (66%, P = .03). Mean final visual acuity was 0.41 +/- 0.40 logMAR in Group P vs 0.43 +/- 0.22 logMAR in Group NP (P = .82). We found no epiretinal membrane (ERM) formation in Group P, whereas 5 cases of ERM (20%) were detected in Group NP (P = .012). The 2 groups did not differ in terms of cystoid macular edema occurrence, macular thickness, or photoreceptor damage. CONCLUSIONS: ILM peeling during vitrectomy in macula-off RD complicated by grade B PVR reduces the need for a second surgery for redetachment or macular pucker. CI - Copyright (c) 2018 Elsevier Inc. All rights reserved. FAU - Foveau, Pauline AU - Foveau P AD - Department of Ophthalmology, University Hospital, Nancy, France. FAU - Leroy, Bertrand AU - Leroy B AD - Department of Ophthalmology, University Hospital, Nancy, France. FAU - Berrod, Jean-Paul AU - Berrod JP AD - Department of Ophthalmology, University Hospital, Nancy, France. Electronic address: jp.berrod@chru-nancy.fr. FAU - Conart, Jean-Baptiste AU - Conart JB AD - Department of Ophthalmology, University Hospital, Nancy, France. LA - eng PT - Comparative Study PT - Journal Article PT - Observational Study DEP - 20180403 PL - United States TA - Am J Ophthalmol JT - American journal of ophthalmology JID - 0370500 SB - IM CIN - Am J Ophthalmol. 2018 Nov;195:244-245. PMID: 30177217 CIN - Am J Ophthalmol. 2018 Nov;195:244. PMID: 30190076 CIN - Am J Ophthalmol. 2018 Dec;196:212-213. PMID: 30274783 CIN - Am J Ophthalmol. 2018 Dec;196:213. PMID: 30286942 MH - Aged MH - Basement Membrane/*surgery MH - Endotamponade/methods MH - Female MH - Follow-Up Studies MH - Humans MH - Macula Lutea/pathology/*surgery MH - Male MH - Middle Aged MH - Retinal Detachment/complications/diagnosis/*surgery MH - Retrospective Studies MH - Tomography, Optical Coherence MH - Treatment Outcome MH - *Visual Acuity MH - Vitrectomy/*methods MH - Vitreoretinopathy, Proliferative/diagnosis/etiology/*surgery EDAT- 2018/04/06 06:00 MHDA- 2019/06/30 06:00 CRDT- 2018/04/06 06:00 PHST- 2017/12/03 00:00 [received] PHST- 2018/03/17 00:00 [revised] PHST- 2018/03/22 00:00 [accepted] PHST- 2018/04/06 06:00 [pubmed] PHST- 2019/06/30 06:00 [medline] PHST- 2018/04/06 06:00 [entrez] AID - S0002-9394(18)30152-1 [pii] AID - 10.1016/j.ajo.2018.03.037 [doi] PST - ppublish SO - Am J Ophthalmol. 2018 Jul;191:1-6. doi: 10.1016/j.ajo.2018.03.037. Epub 2018 Apr 3.