PMID- 29622459
OWN - NLM
STAT- MEDLINE
DCOM- 20181024
LR  - 20181024
IS  - 1874-1754 (Electronic)
IS  - 0167-5273 (Linking)
VI  - 260
DP  - 2018 Jun 1
TI  - Upgrade to his bundle pacing in pacing-dependent patients referred for pulse 
      generator change: Feasibility and intermediate term follow up.
PG  - 88-92
LID - S0167-5273(17)36811-0 [pii]
LID - 10.1016/j.ijcard.2018.01.105 [doi]
AB  - BACKGROUND: Right ventricular pacing (RVP) is associated with an increased 
      incidence of heart failure and may impair cardiac function. Permanent His bundle 
      pacing (HBP) has the potential to physiologically preserve and prevent cardiac 
      dysfunction. This study was to evaluate the feasibility and intermediate 
      follow-up results of upgrade to HBP implantation in patients referred for pulse 
      generator change with long term RVP. METHODS: Twelve of 14 pacing dependent 
      patients who were referred for pulse generator exchange underwent upgrade into 
      HBP successfully in our center. QRS duration, New York Heart Association (NYHA) 
      functional class, echocardiography, use of diuretics and lead parameters were 
      measured at baseline and during the follow-up. RESULTS: Among the 12 patients 
      attempted (mean age, 70.8 +/- 8.9 years, 75% males) successfully, the average 
      ejection fraction (EF) was 52.2 +/- 11.2%. Nine of 12 patients underwent upgrade to 
      HBP, and three patients with EF < 40% underwent HBP and biventricular pacing 
      (BVP) as well. A significant reduction in mean QRS duration was observed compared 
      with pre-implantation, from 157.8 +/- 13.3 ms to 109.3 +/- 16.9 ms (p < 0.001). After 
      6 months follow-up period, median NYHA functional class was improved from 
      2.7 +/- 0.6 to 1.8 +/- 0.6 (p = 0.007) and left ventricular internal diastolic 
      diameter (LVIDd) was reduced from 5.5 +/- 0.4 cm to 5.3 +/- 0.3 cm (p = 0.03). 
      CONCLUSIONS: HBP improves heart failure symptoms with preserved EF by long term 
      RVP. Permanent HBP is feasible and safe for upgrade in patients with long term 
      RVP irrespective of LVEF.
CI  - Copyright (c) 2018. Published by Elsevier B.V.
FAU - Ye, Yang
AU  - Ye Y
AD  - Department of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, 
      Zhejiang University, No. 3 Qingchun East Road, Hangzhou 310016, Zhejiang, 
      People's Republic of China.
FAU - Zhang, Zuwen
AU  - Zhang Z
AD  - Department of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, 
      Zhejiang University, No. 3 Qingchun East Road, Hangzhou 310016, Zhejiang, 
      People's Republic of China.
FAU - Sheng, Xia
AU  - Sheng X
AD  - Department of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, 
      Zhejiang University, No. 3 Qingchun East Road, Hangzhou 310016, Zhejiang, 
      People's Republic of China.
FAU - Wang, Bei
AU  - Wang B
AD  - Department of Diagnostic Ultrasound and Echocardiography, Sir Run Run Shaw 
      Hospital, College of Medicine, Zhejiang University, No. 3 Qingchun East Road, 
      Hangzhou 310016, Zhejiang, People's Republic of China.
FAU - Chen, Shiquan
AU  - Chen S
AD  - Department of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, 
      Zhejiang University, No. 3 Qingchun East Road, Hangzhou 310016, Zhejiang, 
      People's Republic of China.
FAU - Pan, Yiwen
AU  - Pan Y
AD  - Department of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, 
      Zhejiang University, No. 3 Qingchun East Road, Hangzhou 310016, Zhejiang, 
      People's Republic of China.
FAU - Lan, Jingliang
AU  - Lan J
AD  - Department of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, 
      Zhejiang University, No. 3 Qingchun East Road, Hangzhou 310016, Zhejiang, 
      People's Republic of China; Department of Cardiology, Jinhua Hospital of 
      Traditional Chinese Medicine, No. 429 Shuangxixi Road, Jinhua 321017, Zhejiang, 
      People's Republic of China.
FAU - Sun, Yaxun
AU  - Sun Y
AD  - Department of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, 
      Zhejiang University, No. 3 Qingchun East Road, Hangzhou 310016, Zhejiang, 
      People's Republic of China.
FAU - Luan, Yi
AU  - Luan Y
AD  - Department of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, 
      Zhejiang University, No. 3 Qingchun East Road, Hangzhou 310016, Zhejiang, 
      People's Republic of China.
FAU - Jiang, Chenyang
AU  - Jiang C
AD  - Department of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, 
      Zhejiang University, No. 3 Qingchun East Road, Hangzhou 310016, Zhejiang, 
      People's Republic of China.
FAU - Fu, Guosheng
AU  - Fu G
AD  - Department of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, 
      Zhejiang University, No. 3 Qingchun East Road, Hangzhou 310016, Zhejiang, 
      People's Republic of China. Electronic address: fugs@zju.edu.cn.
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Int J Cardiol
JT  - International journal of cardiology
JID - 8200291
SB  - IM
CIN - Int J Cardiol. 2018 Jun 1;260:107-108. PMID: 29622418
MH  - Aged
MH  - Aged, 80 and over
MH  - Atrial Fibrillation/*diagnostic imaging/physiopathology/*therapy
MH  - Bundle of His/*diagnostic imaging/*physiology
MH  - Cardiac Pacing, Artificial/*trends
MH  - Electrocardiography/trends
MH  - Feasibility Studies
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pilot Projects
MH  - Prospective Studies
OTO - NOTNLM
OT  - Biventricular pacing (BVP)
OT  - His bundle pacing (HBP)
OT  - Right ventricular pacing (RVP)
EDAT- 2018/04/07 06:00
MHDA- 2018/10/26 06:00
CRDT- 2018/04/07 06:00
PHST- 2017/11/02 00:00 [received]
PHST- 2017/12/29 00:00 [revised]
PHST- 2018/01/22 00:00 [accepted]
PHST- 2018/04/07 06:00 [entrez]
PHST- 2018/04/07 06:00 [pubmed]
PHST- 2018/10/26 06:00 [medline]
AID - S0167-5273(17)36811-0 [pii]
AID - 10.1016/j.ijcard.2018.01.105 [doi]
PST - ppublish
SO  - Int J Cardiol. 2018 Jun 1;260:88-92. doi: 10.1016/j.ijcard.2018.01.105.