PMID- 29622964
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220316
IS  - 2090-911X (Electronic)
IS  - 1110-2608 (Print)
IS  - 1110-2608 (Linking)
VI  - 69
IP  - 2
DP  - 2017 Jun
TI  - Correlation of corrected QT dispersion with the severity of coronary artery 
      disease detected by SYNTAX score in non-diabetic patients with STEMI.
PG  - 111-117
LID - 10.1016/j.ehj.2016.12.001 [doi]
AB  - INTRODUCTION: Determination of the QT interval dispersion by means of a standard 
      ECG at rest has been widely used for cardiovascular risk assessment during the 
      last 15 years as one of the recent explanations for the development of life 
      threatening ventricular arrhythmias. However, little is known about the relation 
      between QT dispersion and the severity of coronary artery atherosclerosis as 
      defined by SYNTAX score. AIM OF WORK: The present study was done to assess the 
      correlation between QTc dispersion and the severity of coronary artery disease in 
      acute ST elevation myocardial infarction (STEMI) detected by SYNTAX score. 
      PATIENTS AND METHODS: It included 50 patients who were non-diabetic, 
      non-hypertensive and diagnosed as acute STEMI within 6 months undergoing coronary 
      angiography in the cath. lab. of Assiut University Hospital. QT dispersion was 
      calculated as the difference between the longest (QT max) and the shortest QT 
      (QTmin) interval recorded by standard 12 lead ECG. The QT interval was corrected 
      by using Bazett's formula (QTc = QT/square root of R-R interval in seconds). 
      Corrected QT dispersion (QTcd) was defined as the difference between the maximum 
      and minimum QTc for a given heart rate. The SYNTAX score is calculated by syntax 
      calculator, a new tool to grade the complexity of coronary artery disease. 
      RESULTS: Out of 50 participating patients, there were 43 (86%) males with mean 
      age 53.9 +/- 12.1 years. The mean QTc dispersion was 83.1 +/- 20.3 ms, while mean 
      SYNTAX score was 11.6 +/- 6.1. There is a strong positive correlation between QTc 
      dispersion and SYNTAX score. This was not related to age, gender, risk factors or 
      family history of ischemic heart disease. Of note, there was a relationship 
      between QTc dispersion and serum creatinine. CONCLUSIONS: Our study concluded 
      that there is a significant positive correlation between corrected QT dispersion 
      and severity of coronary artery disease as assessed by SYNTAX score.
FAU - Helmy, Hatem
AU  - Helmy H
AD  - Department of Cardiology, Assiut University, Egypt.
FAU - Abdel-Galeel, Ahmed
AU  - Abdel-Galeel A
AD  - Department of Cardiology, Assiut University, Egypt.
FAU - Taha Kishk, Yehia
AU  - Taha Kishk Y
AD  - Department of Cardiology, Assiut University, Egypt.
FAU - Mohammed Sleem, Khaled
AU  - Mohammed Sleem K
AD  - Assiut Policemen Hospital, Egypt.
LA  - eng
PT  - Journal Article
DEP - 20170126
PL  - Germany
TA  - Egypt Heart J
JT  - The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of 
      Cardiology
JID - 9106952
PMC - PMC5839347
OTO - NOTNLM
OT  - QTc dispersion
OT  - STEMI
OT  - SYNTAX score
EDAT- 2018/04/07 06:00
MHDA- 2018/04/07 06:01
PMCR- 2017/01/26
CRDT- 2018/04/07 06:00
PHST- 2016/07/15 00:00 [received]
PHST- 2016/12/24 00:00 [accepted]
PHST- 2018/04/07 06:00 [entrez]
PHST- 2018/04/07 06:00 [pubmed]
PHST- 2018/04/07 06:01 [medline]
PHST- 2017/01/26 00:00 [pmc-release]
AID - S1110-2608(16)30072-2 [pii]
AID - 10.1016/j.ehj.2016.12.001 [doi]
PST - ppublish
SO  - Egypt Heart J. 2017 Jun;69(2):111-117. doi: 10.1016/j.ehj.2016.12.001. Epub 2017 
      Jan 26.